A5101916478- Tea Polyphenols and Effects
- Plant Gene Expression Analysis
- Plant Stress Responses and Tolerance
- Advanced Sensor and Energy Harvesting Materials
- Fermentation and Sensory Analysis
- Food Quality and Safety Studies
- Plant Molecular Biology Research
- Parathyroid Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Forest, Soil, and Plant Ecology in China
- Treatment of Major Depression
- DNA Repair Mechanisms
- Cancer, Hypoxia, and Metabolism
- Chromosomal and Genetic Variations
- Genomics, phytochemicals, and oxidative stress
- Effects and risks of endocrine disrupting chemicals
- Garlic and Onion Studies
- Autophagy in Disease and Therapy
- Per- and polyfluoroalkyl substances research
- Metabolism and Genetic Disorders
- Endoplasmic Reticulum Stress and Disease
- Plant responses to elevated CO2
- Tryptophan and brain disorders
- Circular RNAs in diseases
- Urinary and Genital Oncology Studies
Chengdu Institute of Biology
2025
Chinese Academy of Sciences
2025
University of Chinese Academy of Sciences
2025
Central South University
2024
Tianjin Medical University
2021-2024
Wuyi University
2024
Wuyi University
2024
Nanjing University of Chinese Medicine
2024
The Fifth People’s Hospital of Suzhou
2021-2022
First Affiliated Hospital of Soochow University
2022
Abstract Liver injury is a core pathological process in the majority of liver diseases, yet genetic factors predisposing individuals to its initiation and progression remain poorly understood. Here we show that asialoglycoprotein receptor 1 (ASGR1), lectin specifically expressed liver, downregulated patients with fibrosis or cirrhosis male mice injury. ASGR1 deficiency exacerbates while overexpression mitigates acetaminophen-induced acute CCl4-induced chronic injuries mice. Mechanistically,...
Abstract Existing data on the prognosis and clinicopathological features of patients with metastatic renal cell carcinoma (mRCC) are limited. This study aims to investigate prognostic value different sites in mRCC. A dataset from National Cancer Institute’s Surveillance, Epidemiology, End Results (SEER) database consisting 18 registries (1973–2015) was selected for a retrospective mRCC cohort study. Information included lung, bone, liver, brain. Kaplan–Meier analysis applied compare survival...
Vascular calcification (VC), in which vascular smooth muscle cells (VSMCs) undergo differentiation and osteogenic transition, is a common complication of chronic kidney disease (CKD). Recent findings show that nuclear factor-erythroid-2-related factor 2 (NRF2) an evolutionarily conserved antioxidant beneficial preventing senescence calcification. The roles NRF2 the initiation progression VC CKD still need further investigation. CKD-associated model rats exhibited significant upregulation...
Rosa hugonis is widely distributed in the Hengduan Mountains, Qinling and northern China. It an important candidate species for ecological restoration, given its good adaptability. Here, we present first high-quality chromosome-level assembly of R. based on HiFi reads Hi-C data. The sequencing data were then assembled onto seven pseudochromosomes hugonis. genome sizes 337.92 Mb, with contig N50 length 26.84 Mb. We annotated 36,218 protein-coding genes In summary, sequences provide a genetic...
Dahongpao mother tree ( Camellia sinensis ) is nearly 400 years old and the symbol of Wuyi rock tea. It unclear whether structure function rhizosphere soil microbial community (MD) its cutting (PD) change after planting. In this study, macrogenomics was used to analyze communities, as well explore their relationship with nutrient transformations in MD PD tea trees. The results showed that pH, total nitrogen, phosphorus, potassium, available phosphorus potassium were significantly higher than...
Aerospace breeding is a technique that utilizes spacecraft to position plants in space environment for mutagenesis, which conducive rapid mutagenesis the screening of superior plant varieties. In this study, tea trees with aviation (TM) and those without (CK) were selected as research subjects analyze effects on growth, physiological properties, hormone metabolism trees, further screen characteristic hormones validate their functions. The results showed leaf length, width, area TM...
The quality of the Dahongpao mother tree (Camellia sinensis) remains a mystery to this day. In study, for first time, differences between (MD) and cuttings (PD), in terms odor characteristics taste were analyzed by metabomics. results showed that MD had stronger floral, fruity, green, woody than PD, contributions mainly from dihydromyrcenol, methyl salicylate, 2-isobutylpyrazine, 1,6-dihydrocarveol, gamma-terpineol, linalyl acetate. Further, fresh brisk mellowness significantly higher with...
Abstract Currently, reported physical or chemical methods to produce flexible perovskite thin films rely on the use of expensive single crystal substrates large‐scale precision equipment. Here, a high‐performance ultrasensitive piezoelectric sensor via cost‐effective strategy is developed enable release lead zirconate titanate (PZT) from an inexpensive mica substrate, which are subsequently transferred polyethylene terephthalate substrate. The weak van der Waals interaction between mica/La...
Many studies have shown that sleep deprivation can affect a wide range of tissues and organs, most these effects are related to oxidative stress. Oxidative stress cause functional morphological changes in cells, which closely autophagy apoptosis. In this study, we examined thyroid morphology function, stress, autophagy, apoptosis rats after deprivation. Thyroid hormones, thyroid-stimulating hormone, substances required for the synthesis observations were used evaluate impairment function....
Rock zones have an important influence on the yield and quality of Wuyi rock tea. In this study, OPLS-DA combined with machine learning was used to analyze effects different tea tree varieties physicochemical properties rhizosphere soil, growth leaves using trees in zones. The results showed that had significant soil indexes, enzyme activities, while there little difference between varieties. interaction analysis indexes significantly affected quality, also affecting indexes. main caffeine...
Hepatocellular carcinoma (HCC) is typically fatal, and patients with hepatocellular are usually diagnosed at the late stages. Although treatments for HCC have been rapidly advancing, novel targets still desperately needed, especially targeted therapies. Here, we identified an enriched long non-coding RNA, AC006262.5, associated HCC, that promoted proliferation, migration, invasiveness of cells, both in vitro vivo. In addition, our results revealed AC006262.5 bound to regulated miR-7855-5p, a...
Dahongpao mother tree (
Aerospace mutagenesis can alter the physiological metabolism and growth of tea trees affect leaf quality. In this study, effect aerospace on metabolite content taste characteristics Dahongpao fresh leaves raw were analyzed. The results showed that had little composition total amount metabolites in tea, but significantly changed different metabolites. improved lipids, lignans coumarins, amino acids derivatives, which turn enhanced aroma brisk leaves. increased alkaloids, tannins, flavonoids,...
Introduction The present existing data on the association of metastatic sites and prognosis patients with adrenal malignancy are limited. This study aims to investigate impact different distant metastases pattern survival malignancy. Methods A dataset from National Cancer Institute’s Surveillance, Epidemiology, End Results (SEER) 18 Registries (2000–2017) was selected for a retrospective cohort study. There information distribution lesions in bone, brain, liver, lung SEER database....
Abstract Background Diabetic nephropathy (DN) is the major cause of renal failure, and glomerular podocytes play critical roles in pathogenesis DN by maintaining structure filtration barrier. Klotho Slit-Robo GTP activating protein 2a (SRGAP2a) have been indicated to protective reducing injury, but whether there an internal relationship between these two factors unclear. Methods In this study, we cultured differentiated rat vitro measured SRGAP2a expressions immunofluorescence staining,...
Abstract Background: bladder cancer (BCa) is a common malignancy in the urinary system. But hematogenous metastatic pattern of it was poorly explored. The aim this study to provide better understanding prognosis different distant from stage IV BCa patients and support for making suitable clinical decision. Methods: Surveillance, Epidemiology End Result database (SEER) provided data include 2010 2015. Kaplan–Meier method used evaluate survival BCa. Cox proportional hazards regression model...