A5031138186- Data Visualization and Analytics
- Scientific Computing and Data Management
- Cell Image Analysis Techniques
- Video Analysis and Summarization
- Genomics and Chromatin Dynamics
- Multimedia Communication and Technology
- Gene expression and cancer classification
- Algorithms and Data Compression
- Computer Graphics and Visualization Techniques
- Cancer Genomics and Diagnostics
- Genomic variations and chromosomal abnormalities
- Virtual Reality Applications and Impacts
- Big Data Technologies and Applications
- Augmented Reality Applications
- Web Data Mining and Analysis
- Interactive and Immersive Displays
- Genetic Mapping and Diversity in Plants and Animals
- Wildlife-Road Interactions and Conservation
- Single-cell and spatial transcriptomics
- Music Technology and Sound Studies
TU Wien
2017-2021
Masaryk University
2021
HBH Projekt (Czechia)
2013
Various computational approaches predict chromatin structure, yielding concrete models that position genomic loci in physical space and help reveal genome organization function. While prior visualization research has explored data task abstractions for genomics, the design depicting these three-dimensional (3D) models---and associated genome-mapped data---remains unclear. In this paper, we investigate of with a spatial component. First, systematically survey how 3D are used depicted biology....
Labeling is intrinsically important for exploring and understanding complex environments models in a variety of domains. We present method interactive labeling crowded 3D scenes containing very many instances objects spanning multiple scales size. In contrast to previous methods, we target cases where dozens types are the hierarchical structure scene presents an opportunity choose most suitable level each placed label. Our solution builds on goes beyond techniques medical visualization,...
We present a method for producing documentary-style content using real-time scientific visualization. introduce molecumentaries, i.e., molecular documentaries featuring structural models from biology, created through adaptable methods instead of the rigid traditional production pipeline. Our work is motivated by rapid evolution visualization and it potential in science dissemination. Without some form explanation or guidance, however, novices lay-persons often find difficult to gain insights...
We propose a system to facilitate biology communication by developing pipeline support the instructional visualization of heterogeneous biological data on user-devices. Discoveries and concepts in are typically summarized with illustrations assembled manually from interpretation application heterogenous data. The creation such is time consuming, which makes it incompatible frequent updates measured as new discoveries made. Illustrations non-interactive, when an illustration updated, still...
We present ScaleTrotter, a conceptual framework for an interactive, multi-scale visualization of biological mesoscale data and, specifically, genome data. ScaleTrotter allows viewers to smoothly transition from the nucleus cell atomistic composition DNA, while bridging several orders magnitude in scale. The challenges creating interactive are fundamentally different ways those other domains like astronomy that require representation as well. First, has intertwined scale levels---the DNA is...
We present a method for the browsing of hierarchical 3D models in which we combine typical navigation structures 2D environment-using clicks on nodes, links, or icons-with spatial data visualization. Our approach is motivated by large molecular models, traditional single-scale navigational metaphors are not suitable. Multi-scale phenomena, e. g., astronomy geography, complex to navigate due their spaces and multi-level organization. Models from structural biology addition also densely...
Immersive virtual reality environments are gaining popularity for studying and exploring crowded three-dimensional structures. When reaching very high structural densities, the natural depiction of scene produces impenetrable clutter requires visibility occlusion management strategies exploration orientation. Strategies developed to address crowdedness in desktop applications, however, inhibit feeling immersion. They result nonimmersive, desktop-style outside-in viewing reality. This article...
We present Multiscale Unfolding, an interactive technique for illustratively visualizing multiple hierarchical scales of DNA in a single view, showing the genome at different and demonstrating how one scale spatially folds into next. The DNA's extremely long sequential structure-arranged differently on several distinct levels-is often lost traditional 3D depictions, mainly due to its levels dense spatial packing resulting occlusion. Furthermore, exploration this complex structure is...
The computational modeling of chromatin structure is highly complex and challenging due to the hierarchical organization chromatin, which reflects its diverse biophysical principles, as well inherent dynamism, underlies complexity. variety methods for modeling, are based on different approaches, assumptions scales suggests that there a necessity comprehensive benchmark. This inspired us conduct project at NIH-funded 4D Nucleome Hackathon March 18-21, 2024 University Washington in Seattle,...
We present ChromoSkein, a web-based tool for visualizing three-dimensional chromatin models. The spatial organization of is essential to its function. Experimental methods, namely Hi-C, reveal the conformation but output 2D matrix representation. Biologists leverage simulation bring this information back 3D, assembling 3D shape prediction using matrices as constraints. Our overview existing visualization software shows that available tools limit utility through ineffective shading and lack...
Building-up and running a university-based research group is multi-faceted undertaking. The visualization working at TU Wien (vis-group) has been internationally active over more than 25 years. acting in competitive scientific setting where sometimes contradicting multiple objectives require trade-offs optimizations. Research-wise the performing basic applied visual computing. Teaching-wise involved undergraduate graduate lecturing (medical) computer graphics. To be scientifically requires...