Jaroslav Hambalko

ORCID: 0000-0003-4061-1431
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Lipid metabolism and biosynthesis
  • Plant biochemistry and biosynthesis
  • Diverticular Disease and Complications
  • Enzyme Catalysis and Immobilization
  • Enterobacteriaceae and Cronobacter Research
  • Biofuel production and bioconversion
  • Insect and Pesticide Research

Slovak University of Technology in Bratislava
2019-2023

Czech Academy of Sciences, Institute of Biotechnology
2020

Fatty alcohols (FA-OH) are aliphatic unbranched primary with a chain of four or more carbon atoms. Besides potential industrial applications, fatty have important biological functions as well. In nature, produced part mixture pheromones in several insect species, such moths, termites, bees, wasps, etc. addition, FA-OHs for agricultural example, they may be used suitable substitute commercial insecticides. The insecticides drawbacks associated their preparation, and exert negative impact on...

10.3389/fbioe.2020.593419 article EN cc-by Frontiers in Bioengineering and Biotechnology 2021-01-08

ABSTRACT Erucic acid (C22:1Δ13) has several industrial applications including its use as a lubricant, surfactant and biodiesel composite material constituent. It is produced by plants belonging to the Brassicaceae family, especially high erucic rapeseed. The ability convert oleic into facilitated FAE1. In this study, FAD2 (encoding Δ12-desaturase) was deleted in strain Po1d increase content. Subsequently, FAE1 from Thlaspi arvense overexpressed Yarrowia lipolytica with Δfad2 genotype. This...

10.1093/femsle/fnaa042 article EN FEMS Microbiology Letters 2020-03-01

Abstract The 3‐acetyl‐1,2‐diacylglycerols (acTAGs) are the molecules that structurally similar to triacylglycerols (TAGs). They naturally produced by plants of family Celastraceae and animals such as Cervus nippon Eurosta solidaginis . presence acetate in sn –3 position glycerol backbone confers advantages these compounds, for example, lower viscosity calorific value compared classical TAGs. In this work, gene EeDAcT , which encodes diacylglycerol acetyltransferase a species bush ( Euonymus...

10.1002/yea.3442 article EN Yeast 2019-09-11

One of the most interesting groups fatty acid derivates is group conjugated acids from which researched include: linoleic (CLA) and linolenic (CLNA), are associated with countless health benefits. Sex pheromone mixtures some insect species, including tobacco horn-worm (Manduca sexta), typical for production uncommon C16 long two three double bonds, as opposed to C18 CLA CLNA. In this study, M. sexta desaturases MsexD2 MsexD3 were expressed in multiple strains Y. lipolytica different...

10.3390/jof9010114 article EN cc-by Journal of Fungi 2023-01-14

One of the most interesting groups fatty acid derivates is group conjugated acids, from which researched are linoleic (CLA) and linolenic (CLNA), associated with countless health benefits. Sex pheromone mixture some insect species, including tobacco horn-worm (Manduca sexta), typical for production uncommon C16 long acids two three double bonds, as opposed to C18 CLA CLNA. In this study, M. sexta desaturases MsexD2 MsexD3 were expressed in multiple strains Y. lipolytica different genotypes....

10.20944/preprints202212.0439.v1 preprint EN 2022-12-23
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