A5086899529- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroscience of respiration and sleep
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Family and Patient Care in Intensive Care Units
- Sleep and related disorders
- Mechanical Circulatory Support Devices
- Moyamoya disease diagnosis and treatment
- Delphi Technique in Research
- Tracheal and airway disorders
- Frailty in Older Adults
- Human Health and Disease
- Gender Roles and Identity Studies
- Palliative Care and End-of-Life Issues
- Sleep and Wakefulness Research
- Cerebrovascular and Carotid Artery Diseases
- Physical Education and Training Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inhalation and Respiratory Drug Delivery
- Public Health and Nutrition
- Transplantation: Methods and Outcomes
- Intensive Care Unit Cognitive Disorders
Monash Alfred Psychiatry Research centre
2024-2025
The Alfred Hospital
2006-2025
Monash University
2011-2025
Alfred Health
2014-2025
Austin Health
2024
The study aimed to document the neurobehavioral outcomes of patients referred and treated by a sleep medicine service for moderate severe obstructive apnea (OSA). In particular, we establish proportion who, while appearing have optimal continuous positive airway pressure (CPAP) adherence, did not normalize their daytime sleepiness or neurocognitive function after 3 months CPAP therapy despite effective control OSA.Multicenter clinical-effectiveness study.Three academic centers in...
Rationale: Obstructive sleep apnea (OSA) is a prevalent disease. Often limited clinical resources result in long patient waiting lists. Simpler validated methods of care are needed.Objectives: To demonstrate that nurse-led model can produce health outcomes symptomatic moderate–severe OSA not inferior to physician-led care.Methods: A randomized controlled multicenter noninferiority trial was performed. Of 1,427 potentially eligible patients at 3 centers, 882 consented the trial. these, 263...
<h3>Background</h3> Obesity hypoventilation syndrome (OHS) is the most common indication for home ventilation, although optimal therapy remains unclear, particularly severe disease. We compared Bi-level and continuous positive airways pressure (Bi-level airway (PAP); CPAP) treatment of OHS. <h3>Methods</h3> conducted a multicentre, parallel, double-blind trial initial OHS, with participants randomised to nocturnal PAP or CPAP 3 months. The primary outcome was frequency failure (hospital...
Oxygen is a life-saving therapy but, when given inappropriately, may also be hazardous. Therefore, in the acute medical setting, oxygen should only as treatment for hypoxaemia and requires appropriate prescription, monitoring review. This update to Thoracic Society of Australia New Zealand (TSANZ) guidance on brief practical resource all healthcare workers involved with administering adults setting. It does not apply intubated or paediatric patients. Recommendations are made following six...
Abstract This Thoracic Society of Australia and New Zealand Guideline on the provision home oxygen therapy in adults updates a previous from 2015. The is based upon systematic review meta‐analysis literature to September 2022 strength recommendations GRADE methodology. Long‐term (LTOT) recommended for its mortality benefit patients with COPD other chronic respiratory diseases who have consistent evidence significant hypoxaemia at rest (PaO2 ≤ 55 mm Hg or PaO2 ≤59 presence hypoxaemic...
Abstract Background and Aims Ward‐delivered non‐invasive respiratory supports (NIRS) (conventional oxygen therapy (COT), high‐flow nasal (HFNO), continuous positive airway pressure (CPAP) ventilation (NIV)), are often used to treat hospitalised patients with acute failure (ARF) both in high acuity general wards. This study aimed describe the processes of care adopted examine patient outcomes from a specialist, ward‐delivered NIRS service caring for people COVID‐19 wards or unit (RCU)....
Background: High-flow nasal oxygen (HFNO) therapy delivers humidified, heated air with flow rates of up to 60 L/min entrained. HFNO has advantages over conventional therapy, including precise and reliable fraction inspired delivery, therefore is recommended as first-line treatment for people acute hypoxaemic respiratory failure. Objectives: This pilot study aimed determine the feasibility acceptability domiciliary high (NHF) without entrained chronic obstructive pulmonary disease (COPD)...
ABSTRACT Background and objective Non‐invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model care remains unknown. Methods We conducted a prospective observational non‐inferiority study comparing three models NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant round), high dependency unit (HDU) (1:2 twice daily round) an intensive (ICU) (1:1 similar teaching tertiary hospitals. Changes...
Conventional oxygen therapy (COT) is the cornerstone of management for hypoxaemia associated with acute respiratory failure (ARF) in wards. COT implementation guidance provided local health documents (LHGDs). This study aimed to identify ward-delivered adult LHGDs Australian services and assess their content accuracy.
The benefits of domiciliary non-invasive ventilation (NIV) post lung transplantation (LTx) have not previously been described. This was a single-centre retrospective audit patients requiring NIV post-LTx. Our aim to describe indications for and outcomes in chronic allograft dysfunction (CLAD) diaphragmatic palsy.All post-LTx between 2010 June 2016 were assessed. indications, respiratory function patient collected.Out 488 LTx recipients, 20 identified as over the 6.5-year study period. most...