A5100701331- Microbial infections and disease research
- Plant Virus Research Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Immune cells in cancer
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Advanced Fluorescence Microscopy Techniques
- vaccines and immunoinformatics approaches
- Psoriasis: Treatment and Pathogenesis
- Plant Disease Management Techniques
- Polymer Surface Interaction Studies
- ZnO doping and properties
- Galectins and Cancer Biology
- Copper-based nanomaterials and applications
- Plasmonic and Surface Plasmon Research
- Magneto-Optical Properties and Applications
- Inflammation biomarkers and pathways
- Nanoplatforms for cancer theranostics
- Poxvirus research and outbreaks
- Immune Cell Function and Interaction
- Veterinary medicine and infectious diseases
- Exercise and Physiological Responses
- Dendrimers and Hyperbranched Polymers
- Advancements in Transdermal Drug Delivery
Dalian Medical University
2023-2025
Chongqing Medical University
2023-2025
Second Affiliated Hospital of Chongqing Medical University
2023-2025
Southwest Hospital
2025
Army Medical University
2025
Xihua University
2024
Dankook University
2024
Chongqing Cancer Hospital
2022-2024
Chongqing University
2022-2024
South China University of Technology
2023
Therapeutic strategies based on modulation of microRNAs (miRNAs) activity hold much promise for cancer therapy, but clinical applications, the efficient delivery miRNAs to tumor cells or tissues remains a great challenge. In this work, microRNA‐181b inhibitor (anti‐miR‐181b) is successfully condensed into polyethyleneimine (PEI)‐modified and folate receptor (FR)‐targeted PEGylated gold nanocages (AuNCs). This system designated as anti‐miR‐181b/PTPAuNCs nanocomplexes (PTPAuNC‐NPs), which...
This work created a simple electrochemical cortisol sensing method based on ZnO nanostructures to track high-performance athletes' stress levels and recuperation times. nanorods (ZnO NRs) were deposited the surface of glassy carbon electrode (ZnO/GCE) using an electrodeposition technique. Subsequently, 3-aminopropyltriethoxysilane (APTES) was applied in order improve antibody (C-M ab) immobilization stability ab/APTES/ZnO/GCE). Successful C-M ab APTES/ZnO/GCE NRs GCE confirmed by structural...
Postoperative tumor recurrence remains a predominant cause of treatment failure. In this study, we developed an in situ injectable hydrogel, termed MPB-NO@DOX + ATRA gel, which was locally formed within the resection cavity. The gel fabricated by mixing thrombin solution, fibrinogen solution containing all-trans retinoic acid (ATRA), and Mn/NO-based immune nano-activator MPB-NO@DOX. promoted differentiation cancer stem cells, inhibited cell migration, affected polarization tumor-associated...
Abstract Macrophages hold a critical position in maintenance of hepatic homeostasis and injury repair processes acute chronic liver diseases. TIM3 is promising protector MCD-induced steatohepatitis injury. However, we recently find as driver fibrosis MCD/HFD-induced This study aims to explore how macrophage drivers NAFLD-associated well identify subtype fibrotic patients suitable for anti-TIM3 immunotherapy. Here, found that was highly expressed macrophages long-term MCD- or HFD-fed mice...
A simple and versatile method for the fabrication of highly stable well-defined protein/cell arrays was developed.
Pasteurella multocida is an important pathogen that leads to a range of diseases have severe economic consequences on cattle production. In order develop effective cross‑protective component vaccine, immunoproteomics approach was used analyze outer membrane proteins (OMPs) the P. serotype A, B and F strains. Candidate antigen molecules from whole genome were screened via linear trap quadrupole mass spectrometry bioinformatics analysis, reactogenicity candidate analyzed cloning, expression,...
As one of the excellent piezoelectric materials, ceramic has been widely used to develop a highly precise displacement measurement system, which is key part scanning probe system high-precision measuring instrument.Based on micro/nano structures can be easily and accurately detected by instrument system.However, due limitations caused character hysteresis nonlinearity, it difficult further improve precision system.In this work, we present novel method based quantum spin effect.The nitrogen...
Tumor recurrence after radiofrequency ablation (RFA) affects the survival rate of patients and limits its clinical application. around area may be related to thermal injury hepatocytes (HCs) tumor, but specific mechanism is still unclear. A liver cancer mouse model was established via RFA in C57BL/6 mice. Primary HCs Kupffer cells (KCs) were isolated cultured assess their sensitivity MTT assay. Flow cytometry used macrophage polarization. Furthermore, Western blotting co-immunoprecipitation...
Abstract Background In hepatocellular carcinoma (HCC), myeloid-derived suppressor cells (MDSCs) play a vital role in the tumor immune microenvironment, significantly impacting initiation and progression. The study of genes linked to MDSCs predicting progression HCC is significant scholarly significance. Method Acquiring comprehensive single cell RNA sequencing (scRNA-seq) dataset from GEO extract valuable information detect distinct subgroups through application clustering dimensionality...