A5024169108- Nutritional Studies and Diet
- Agriculture Sustainability and Environmental Impact
- Diet and metabolism studies
- Phytochemicals and Antioxidant Activities
- Food composition and properties
- Food Waste Reduction and Sustainability
- Metabolomics and Mass Spectrometry Studies
- Photosynthetic Processes and Mechanisms
- Consumer Attitudes and Food Labeling
- Biochemical Analysis and Sensing Techniques
- Environmental Impact and Sustainability
- Seed and Plant Biochemistry
- Nanoplatforms for cancer theranostics
- Proteins in Food Systems
- Fermentation and Sensory Analysis
- Nanoparticle-Based Drug Delivery
- Berry genetics and cultivation research
- Plant Gene Expression Analysis
- Adipose Tissue and Metabolism
- Aquatic Ecosystems and Phytoplankton Dynamics
- Meat and Animal Product Quality
- Microbial Metabolites in Food Biotechnology
- GABA and Rice Research
- Pineapple and bromelain studies
- Muscle metabolism and nutrition
University of Turku
2010-2025
University of Eastern Finland
2014-2024
Finland University
2023
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive nanomedical tools because of their unique properties such immune escape, long blood circulation time, specific molecular recognition and cell targeting. However, the integrity coating on NPs, a key metrics related to quality these biomimetic-systems resulting biomedical function, has remained largely unexplored. Here, we report fluorescence quenching assay probe coating. In contradiction common assumption...
Cell membrane (CM) coating technology is increasingly being applied in nanomedicine, but the entire procedure including adsorption, rupture, and fusion not completely understood. Previously, we showed that majority of biomimetic nanoparticles (NPs) were only partially coated, mechanism underlying this partial remains unclear, which hinders further improvement technique. Here, show an intermediate state due to adsorption CM fragments or vesicles, latter could eventually be ruptured under...
This study investigated the effects of including 5, 10 or 15% oat bran, wheat combination both on physicochemical properties extruded pea protein-based meat analogues. The extrudates were analysed for colour, textural properties, microstructure, protein-protein interactions and protein solubility. In vitro digestibility (IVPD) was from intermediate end products. IVPD varied between 48 91% highest in PI flour lowest extrudate. Higher tensile cutting strengths observed one direction which is a...
Strawberry leaves contain high amounts of diverse phenolic compounds potentially possessing defensive activities against microbial pathogens and beneficial properties for human health. In this work, young strawberry plants were treated with two plant activators, S-methylbenzo-1,2,3-thaidiazole-7-carbothiate (BTH) birch wood distillate. Phenolic from activator-treated control subjected to quantitative analyses by HPLC-DAD, HPLC-ESI-MS, microQTOF ESI-MS. Thirty-two different detected...
Increasing epidemiological and experimental data now emphasize that a diet rich in vegetables fruits confers many health benefits. Functional products containing elevated levels of bioactive compounds are attracting considerable attention due to their potential lower the risk chronic diseases associated huge healthcare costs. On global scale, there is an increasing demand for berries fruits, since they natural polyphenol-rich raw material be incorporated into functional foods, nutraceuticals...
Strawberry (Fragaria × ananassa Duch.) contains many secondary metabolites potentially beneficial for human health, and several of these compounds contribute to strawberry sensory properties, as well. In this study, three cultivars grown both conventionally organically were subjected nontargeted metabolite profiling analysis with LC-qTOF-ESI-MS descriptive evaluation by a trained panel. Combined metabolome data (PLS model) revealed that 79% variation in the explained 88% profiles. Flavonoids...
Abstract Purpose Substitution of animal-source foods with plant-based alternatives requires product-specific information from both the environmental and nutritional perspectives. The use nutrient indices as functional units (nFUs) in Life Cycle Assessment (LCA) food products has been developed to integrate aspects into method (nLCA). However, methodological approaches vary because execution LCA always depends on context. Methods We present a approach for nLCA protein-rich...
Faba bean ingredients are attracting interest for their suitability in producing protein-rich plant-based foods. However, sensory characteristics (e.g., bitterness) challenge consumer acceptance. This study explored variations the metabolome and links between metabolites attributes using UHPLC-qTOF-MS/MS analysis of faba flour, two protein concentrates, isolate. Partial Least Squares regression identified contributing to descriptors, it was validated against VirtuousMultiTaste platform....
Abstract According to existing food processing classification systems, plant-based protein-rich (PBPR) foods are often considered ‘ultra-processed’—and therefore perceived as unhealthy—despite their ability provide various bioactive compounds beneficial for human health. Here we used a non-targeted metabolomics approach analyse the impact of on biochemical composition PBPR foods. Our results show that systems may questionable categories without considering overall composition, including...
Acclimation of cyanobacteria to environmental conditions is mainly controlled at the transcriptional level, and σ factors RNA polymerase have a central role in this process. The model cyanobacterium Synechocystis sp. PCC 6803 has four non-essential group 2 (SigB, SigC, SigD SigE) that regulate global metabolic responses various adverse conditions. Here we show although none essential for major realignments induced by short period nitrogen starvation, quadruple mutant without any triple...
The ability to provide adequate nutrition is considered a key factor in evaluating the sustainability of foods and diets. Nutrient indices are used as functional units (FU) life cycle assessment include nutritional performance environmental product. Several general food-group-specific nutrient exist but many lack validation, particularly when FU. In addition, selection strategies reference for intake can vary considerably among studies. To validate intake-based product-group-specific...
ABSTRACT Low‐gluten diets (LGD) are also widely followed by people not suffering from coeliac disease. This study compared oats and rice as the main cereal source of an LGD in metabolically challenged volunteers. Volunteers ( n = 69) were randomly assigned to LGD, which was either rich or rice, for 6 weeks. Before after intervention, concentrations total cholesterol, LDL‐C, HDL‐C, triacylglycerols, free fatty acids, glucose, insulin measured fasting plasma samples; volunteers completed 4‐day...
Abstract BACKGROUND The non‐edible parts of horticultural crops, such as leaves, contain substantial amounts valuable bioactive compounds which are currently only little exploited. For example, strawberry ( Fragaria × ananassa ) leaves may be a promising bioresource for diverse health‐related applications. However, product standardization sets real challenge, especially when the leaf material comes from varying cultivars. first step towards better quality control berry fruit leaf‐based...
Acclimation of cyanobacteria to environmental changes includes major in the gene expression patterns partly orchestrated by replacement a particular σ subunit with another RNA polymerase holoenzyme. The cyanobacterium Synechocystis sp. strain PCC 6803 encodes nine factors, all belonging σ(70) family. Cyanobacteria typically encode many group 2 factors that closely resemble principal factor. We inactivated three out four simultaneously possible combinations and found triple inactivation...
Non-alcoholic fatty liver disease (NAFLD) pathogenesis remains poorly understood due to the complex metabolic and inflammatory changes in liver. This study aimed elucidate hepatic events related inflammation lipid metabolism their linkage with alterations during NAFLD American lifestyle-induced obesity syndrome (ALIOS) diet-fed mice. Forty-eight C57BL/6J male mice were fed ALIOS diet (n=24) or control chow for 8, 12, 16 weeks. At end of each timepoint, eight sacrificed where plasma...
Abstract Purpose Recent methodological developments have integrated nutritional aspects into life cycle assessment (LCA) by using nutrient indices as functional units (nFUs). Previous focused on protein-rich foods, but environmental impacts and composition vary across products in other product groups, highlighting the need to develop nFUs also for groups. Here, we present product-group-specific vegetables, fruit berries, sources of carbohydrates an extension our previous study protein...