A5090677299- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Advanced Memory and Neural Computing
- EEG and Brain-Computer Interfaces
- Biomarkers in Disease Mechanisms
- Advanced biosensing and bioanalysis techniques
- Ion channel regulation and function
- Neuroinflammation and Neurodegeneration Mechanisms
- Electrochemical Analysis and Applications
- Phagocytosis and Immune Regulation
- Molecular Sensors and Ion Detection
- Conducting polymers and applications
HUN-REN Institute of Experimental Medicine
2023-2024
Brainvest (Hungary)
2023
University of Pannonia
2020-2021
Eötvös Loránd University
2018-2021
Pázmány Péter Catholic University
2020-2021
HUN-REN Centre for Energy Research
2018-2021
Hungarian Academy of Sciences
2018
Elements of the immune system particularly that innate immunity, play important roles beyond their traditional tasks in host defense, including manifold nervous system. Complement-mediated synaptic pruning is essential developing and healthy functioning brain becomes aberrant neurodegenerative disorders. C1q, component classical complement pathway, plays a central role tagging synapses for elimination; however, underlying molecular mechanisms interaction partners are mostly unknown. Neuronal...
A library of twelve novel fluorescent GFP chromophore based chemosensors (GFZnPs) was prepared for the detection Zn2+ in biological samples with two-photon microscopy. The presented compounds are hybrids chelator 8-aminoquinoline motif and chromophore, exploiting enhancing properties natural chromophore. In probes, quenching rotation around benzylidene carbon is conditionally blocked upon binding, resulting a response to ion. GFZnPs have an efficient simple synthesis making them one most...
Abstract Thiol‐ene/acrylate, a softening polymer material, rapidly gained attention during the past few years as substrate of intracortical probes, soft polymers can mitigate foreign body response by reducing mechanical mismatch between neural implant and surrounding brain tissue. This paper presents comprehensive analysis thiol‐ene/acrylate based microECoG (micro – electrocorticography, μECoG) device with 31 sputtered iridium oxide electrodes. Long‐term electrochemical measurements provide...
Intracranial EEG (iEEG) or micro-electrocorticography (µECoG) microelectrodes offer high spatial resolution in recordings of neuronal activity from the exposed brain surface. Reliability dielectric substrates and conductive materials these devices are under intensive research terms functional stability biological environments.The aim our study is to investigate electroplated platinum recording sites on 16-channel, 8 micron thick, polyimide based, flexible µECoG arrays implanted underneath...
Anatomically, connections form the fundamental brain network, functionally different types of oscillatory electric activities are creating a temporarily connected fraction anatomical connectome generating an output to motor system. Schizophrenia can be considered as disease, in which sensory input generates schizophrenia specific temporary and signal processing becomes diseased showing hallucinations adverse behavioral reactions. In this work, flexible, 32-channel polymer microelectrode...
Transparent epidural devices that facilitate the concurrent use of electrophysiology and neuroimaging are arising tools for neuroscience. Testing biocompatibility evoked immune response novel implantable is essential to lay down fundamentals their extensive application. Here we present an immunohistochemical evaluation a Parylene HT/indium-tin oxide (ITO) based electrocorticography (ECoG) device, provide long-term data at three chronic implantation lengths. We implanted HT/ITO ECoG...
The hippocampus has a crucial role in the formation, consolidation and recall of memories as well navigation related processes. These functions are focus neuroscience different disciplines have contributed to this research field for decades. Two-photon imaging awake animals is valuable new aspect these observations, especially when it supported by electrophysiology. In study, we applied high speed two-photon hippocampal through chronically implanted, soft, transparent microelectrode (STM)...