Lenka Štěpánková

ORCID: 0000-0003-4085-2390
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About
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Research Areas
  • Smoking Behavior and Cessation
  • Obesity, Physical Activity, Diet
  • Behavioral Health and Interventions
  • School Health and Nursing Education
  • Nicotinic Acetylcholine Receptors Study
  • Nutrition and Health Studies
  • Obesity and Health Practices
  • Psychology of Moral and Emotional Judgment
  • Health and Wellbeing Research
  • Cardiovascular Disease and Adiposity
  • Religion, Spirituality, and Psychology
  • Inflammatory Bowel Disease
  • Tea Polyphenols and Effects
  • Global Public Health Policies and Epidemiology
  • Cardiovascular Health and Risk Factors
  • Gut microbiota and health
  • Health Promotion and Cardiovascular Prevention
  • Influenza Virus Research Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Eating Disorders and Behaviors
  • Cultural Differences and Values
  • Evolutionary Game Theory and Cooperation
  • Medication Adherence and Compliance
  • Health disparities and outcomes
  • Adipokines, Inflammation, and Metabolic Diseases

Charles University
2009-2024

General University Hospital in Prague
2016-2024

Smoking is more prevalent among people with depression. Depression may make cessation difficult and affect depression symptoms. The aims of this study were to assess the associations between (1) baseline 1-year smoking abstinence (2) change in Observational using data collected routinely a clinic Czech Republic from 2008 2014. Aim 1: N = 3775 patients; 14.3% reported mild 15.4% moderate/severe levels measured Beck's Inventory (BDI-II). Logistic regressions assessed if level predicted...

10.1007/s12160-016-9869-6 article EN cc-by Annals of Behavioral Medicine 2016-12-29

Human zonulin is a protein that increases permeability in the epithelial layer of small intestine by reversibly modulating intercellular tight junctions. There not sufficient information available about zonulin's participation inflammatory bowel diseases (IBD). The aim this study was therefore to investigate fecal and serum IBD patients its relation disease localization, behavior smoking status.Forty forty healthy persons were examined for concentrations competitive ELISA (DRG International...

10.1016/j.plabm.2017.09.001 article EN cc-by-nc-nd Practical Laboratory Medicine 2017-09-23

Cross-study comparisons of effect sizes suggest that varenicline is more effective than nicotine replacement therapy (NRT) in aiding smoking cessation, but evidence from direct limited. This study compared biochemically verified 52-week sustained abstinence rates smokers attending the same clinical service according to whether they used or NRT their quit attempt.This was a prospective cohort 855 large cessation clinic who choice product attempt. All received behavioural support programme and...

10.1111/add.12219 article EN Addiction 2013-05-13

Objectives Most people gain weight on stopping smoking but the extent of varies greatly. Interventions aimed at all quitters to prevent cessation have proven unpopular targeting who gained excess immediately after quitting may improve uptake and cost-effectiveness. We examined whether early large postcessation predicts overall gain. Design Retrospective cohort study. Setting Primary care setting—smoking centre in Prague, Czech Republic. Participants Out 3537 patients treated between 2005...

10.1136/bmjopen-2018-023987 article EN cc-by-nc BMJ Open 2018-12-01

Weight concerns are prevalent in smokers and may reduce the success rate of quitting. This concept has been primarily studied on US populations it is unknown how weight differ cross-culturally. study examined role concern European wishing to stop smoking.A sample 593 (299 men 294 women, mean age 38 years) utilizing Centre for Tobacco-Dependent Prague, Czech Republic, between 2010 2013 were studied. assessed at baseline prior treatment by evidence-based smoking methods. Abstinence was...

10.1093/ntr/ntw276 article EN Nicotine & Tobacco Research 2016-10-11

There has been a noticeable relative increase in psychiatric comorbidities among smokers as opposed to the general population. This is likely due comparatively slower decrease smoking prevalence individuals with mental health conditions. study aims assess trend of past or current disorders seeking specialized cessation assistance.We conducted retrospective single-centre observational presence such anxiety, depression, bipolar affective disorder, schizophrenia personal history 6,546 who...

10.1186/s12888-023-05115-x article EN cc-by BMC Psychiatry 2023-08-24

Higher prevalence of smoking among depressed patients, as well the risk depression in smokers, is documented. The proportion patients with a history those seeking intensive treatment tobacco dependence also high. In contrast, evidence success this subgroup controversial. aim study was to compare abstinence rates after smokers and without depression.We reviewed retrospective data from 1,730 Prague, Czech Republic. History defined past diagnosis or current depression. After 1-year,...

10.5888/pcd10.130051 article EN public-domain Preventing Chronic Disease 2013-09-13

The mechanisms behind the changes of body weight after smoking cessation are only partially understood. To this end, we explored possible effects on incretin hormones, leptin and selected anthropometric, biochemical other hormonal parameters. Twenty-two non-obese male adult smokers attending an ambulatory program in Prague, Czech Republic, were examined at baseline. Thirteen patients (mean age 37.92±2.66 years, mean mass index 25.56±0.69 kg/m2) successfully quit three months cessation;...

10.33549/physiolres.933154 article EN cc-by-nc Physiological Research 2016-08-16

Objectives: The primary aim of a hospital is to promote/improve and restore health, thus smoking, whether in its passive or active form, should be banned all premises for the benefit employees patients alike. Global Network Tobacco Free Healthcare Services (GNTH) an international non-profit association formed 1999. GNTH's mission implement tobacco-free policies create healthy workplace patients' environment; help physicians, nurses, other healthcare workers stop smoking; educate caregivers...

10.21101/cejph.a6172 article EN Central European Journal of Public Health 2020-10-18

Plasma values of nicotine and its metabolites are highly variable, this variability has a strong genetic influence. In our study, we analysed the impact common polymorphisms associated with smoking on plasma nicotine, their ratios investigated potential effect these metabolite successful treatment tobacco dependence.Five variants (rs16969968, rs6474412, rs578776, rs4105144 rs3733829) were genotyped in group dependent adult smokers (n=103). All underwent intensive for dependence; 33 still...

10.5507/bp.2019.058 article EN cc-by Biomedical Papers 2019-12-02

To compare success rates and characteristics of smokers treated a second time by smokers' clinic with their first treatment.Retrospective cohort study.Tobacco Dependence Treatment in Prague, Czech Republic, between 2005 2017.A total 5225 either once (n = 5006, single treatment sample, SS) or also 219, re-treated RS), on average 4.47 years after the visit.Smokers received intensive tobacco dependence pharmacotherapy options. Outcomes were evaluated 1 year. In case failure relapse,...

10.1111/add.15175 article EN Addiction 2020-06-27

Objectives: Our aim was to examine the relationship between weight concerns (WC) and smoking cessation. Methods: WC assessed before cessation treatment in 671 adult patients who completed a 12-month follow-up visit at Centre for Tobacco-Dependent, Prague, Czech Republic, from 2013 through 2019. We evaluated abstinence rate follow-up. Results: Among 669 with baseline (mean age, 43.4 years), 47% were women (145/306) 21% men (78/363). No association existed 12 months. Smokers obesity had...

10.5993/ajhb.47.2.21 article EN cc-by-nc-nd American Journal of Health Behavior 2023-04-30

: There is little information on changes in the process and outcomes of intensive tobacco dependence treatment during COVID-19 pandemic. The following characteristics were evaluated: interest treatment, number face-to-face or telephone follow-ups, duration pharmacotherapy use, success rate. aim our study was to compare patients who entered programmes evaluate one-year rate three years before after

10.3390/medicina60091459 article EN cc-by Medicina 2024-09-06
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