Francisco Javier Ruano

ORCID: 0000-0003-4098-3446
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About
Contact & Profiles
Research Areas
  • Allergic Rhinitis and Sensitization
  • Drug-Induced Adverse Reactions
  • Food Allergy and Anaphylaxis Research
  • Contact Dermatitis and Allergies
  • Asthma and respiratory diseases
  • Urticaria and Related Conditions
  • Pharmaceutical studies and practices
  • Respiratory and Cough-Related Research
  • Occupational exposure and asthma
  • Dermatology and Skin Diseases
  • Pediatric health and respiratory diseases
  • Inhalation and Respiratory Drug Delivery
  • Indoor Air Quality and Microbial Exposure
  • Immunodeficiency and Autoimmune Disorders
  • Infant Health and Development
  • Eosinophilic Esophagitis
  • Mast cells and histamine
  • Blood disorders and treatments
  • Postharvest Quality and Shelf Life Management
  • Exercise and Physiological Responses
  • Pharmacological Receptor Mechanisms and Effects
  • Cardiovascular Effects of Exercise
  • COVID-19 and healthcare impacts
  • Herbal Medicine Research Studies
  • Cardiac Structural Anomalies and Repair

Hospital Universitario Infanta Leonor
2012-2024

Universidad Complutense de Madrid
2015-2023

Instituto de Salud Carlos III
2018

Hospital Universitario La Paz
2017

Marqués de Valdecilla University Hospital
2017

Instituto de Historia
2017

Ayuntamiento de Sevilla
2017

The University of Texas Medical Branch at Galveston
2015

Hallym University
2015

Hospital Regional Universitario de Málaga
2015

An increasing number of patients show immediate selective hypersensitivity reactions to clavulanic acid (CLV) and amoxicillin (AX), probably due their increased prescription. The maintenance this response should be established.To assess that the AX or CLV is maintained after repeated administration penicillin G (PG)/penicillin V (PV) AX.Patients with proven (Group A) B) were included. Diagnosis was performed using skin tests major minor determinants PG (PPL/MDM), by drug provocation test...

10.1111/all.12636 article EN Allergy 2015-04-24

Clinical Implications•This study describing the effects of coronavirus disease 2019 pandemic in a selected group patients with severe asthma suggests that may not be or cause exacerbations such patients. •This During (COVID-19) pandemic, caused by acute respiratory syndrome 2 (SARS-CoV-2), Spain has been one most severely affected countries Europe. As time writing, country reported 213,435 confirmed cases disease, approximately 10% which have required intensive care, and 24,543 people died...

10.1016/j.jaip.2020.06.033 article EN other-oa The Journal of Allergy and Clinical Immunology In Practice 2020-06-27

Cow milk and egg are the most frequent causes of food allergy in first years life. Oral immunotherapy (OIT) has been investigated as an alternative to avoidance diets. No clinical practice guidelines on management OIT with currently available. Objectives: To develop for based available scientific evidence opinions experts.A review was made studies published between 1984 June 2016, doctoral theses Spain, summaries communications at meetings (SEAIC, SEICAP, EAACI, AAAAI), consensus opinion...

10.18176/jiaci.0178 article EN Journal of Investigational Allergology and Clinical Immunology 2017-06-09

Abstract Background Beta‐lactams generate different allergenic determinants that induce selective or cross‐reactive drug hypersensitivity reactions (DHRs). We aimed to identify the drugs involved, selectivity of response, mechanism, and value diagnostic tests for establishing a diagnosis in children evaluated DHRs beta‐lactams. Methods Prospective study evaluating aged under 16 years reporting Reactions were classified as immediate non‐immediate reactions. The workup included sIgE, skin...

10.1111/pai.13608 article EN Pediatric Allergy and Immunology 2021-07-29

Clavulanate, a beta-lactam associated with amoxicillin, is frequently prescribed in patients at all ages. Recent data implicate amoxicillin-clavulanate up to 80% of allergy cases. We assessed clavulanate's role inducing allergic reactions this combination treatment, focus on selective immediate reactions.Adults (≥ 16 years) reporting history were evaluated through allergological workup, using modified European Academy Allergy and Clinical Immunology guidelines. Patients first underwent skin...

10.4168/aair.2023.15.2.201 article EN Allergy Asthma and Immunology Research 2023-01-01

Allergy can start at early ages, with genetic and environmental factors contributing to its development.The study aimed describe the pattern of sensitisation allergy in children adolescents Spanish versus Moroccan ancestry but born same rural area Spain.Participants were (3-19 years) or descent, Blanca, Murcia (Spain). A detailed questionnaire was completed, skin prick tests performed assess reactions most prevalent pollen allergens (O. europaea, P. pratense, S. kali, C. arizonica,...

10.2147/jaa.s370279 article EN cc-by-nc Journal of Asthma and Allergy 2022-09-01

Exposure to cat allergens is often difficult avoid. Here, we evaluated the safety and effectiveness of a depigmented, polymerized epithelium extract (Dpg-pol-cat) for treatment allergic rhinoconjunctivitis asthma.

10.1159/000541838 article EN International Archives of Allergy and Immunology 2024-11-14
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