- Endoplasmic Reticulum Stress and Disease
- Diabetes and associated disorders
- Genetic Associations and Epidemiology
- Acute Myeloid Leukemia Research
- Immune Cell Function and Interaction
- Neurofibromatosis and Schwannoma Cases
- Cognitive Abilities and Testing
- Drug-Induced Ocular Toxicity
- Neuroblastoma Research and Treatments
- Retinoids in leukemia and cellular processes
- Sex and Gender in Healthcare
- Cancer Research and Treatments
- Computational Drug Discovery Methods
- Birth, Development, and Health
- Nutrition, Genetics, and Disease
- Malaria Research and Control
- Trypanosoma species research and implications
- Adrenal and Paraganglionic Tumors
The University of Texas Southwestern Medical Center
2023-2024
Southwestern Medical Center
2023-2024
University of Florida
2015-2019
Florida College
2019
African Americans are 40% more likely to be afflicted with hypertension than non-Hispanic, white Americans, resulting in a 30% higher instance of mortality due cardiovascular disease. There is debate about the relative contributions genetic and sociocultural risk factors racial disparity hypertension. We assayed three Alu insertion polymorphisms located ACE (angiotensin 1 converting enzyme), PLAT (plasminogen activator, tissue), WNK1 (lysine deficient protein kinase 1) genes. also estimated...
Antimalarial drugs are a key tool in malaria elimination programs. With the emergence of artemisinin resistance southeast Asia, an effort to identify molecular markers for surveillance resistant parasites is underway. Non-synonymous mutations kelch propeller domain (K13-propeller) Plasmodium falciparum have been associated with samples from but additional studies needed characterize this locus other P. populations different levels use. Here, we sequenced K13-propeller 82 Haiti, where limited...
This case describes an unusual presentation of a young adult with very late recurrence stage MS neuroblastoma over 20 years after initial diagnosis. Tumor histology at relapse demonstrated ganglioneuromatous foci within her undifferentiated tumor. In combination evidence altered catecholamine metabolism, it proposes for dedifferentiation unresected lesions as the etiology disease. An additional, compelling component is overall positive treatment response patient relapsed despite poor...