Hala Mahfouz

ORCID: 0000-0003-4110-3746
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About
Contact & Profiles
Research Areas
  • Wound Healing and Treatments
  • Diagnosis and Treatment of Venous Diseases
  • Gut microbiota and health
  • Drug-Induced Hepatotoxicity and Protection
  • Clinical Nutrition and Gastroenterology
  • Ginseng Biological Effects and Applications
  • Inflammasome and immune disorders
  • Inflammatory Bowel Disease
  • RNA modifications and cancer
  • Tendon Structure and Treatment
  • Metabolism and Genetic Disorders
  • Moringa oleifera research and applications
  • Pregnancy and preeclampsia studies
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Reproductive System and Pregnancy
  • Antifungal resistance and susceptibility
  • Organ Transplantation Techniques and Outcomes
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Plant-based Medicinal Research
  • Communication and COVID-19 Impact
  • Pharmacological Effects of Natural Compounds
  • Potato Plant Research
  • Botanical Studies and Applications

Kafrelsheikh University
2020-2025

Research Institute of Ophthalmology
2024

Gut modulation by multi-strain probiotics (MSPs) is considered an effective strategy for treating inflammatory bowel disease (IBD). The combination of nanomaterial-based MSPs can improve their viability and resistance allow targeted release in the gastrointestinal tract to be achieved. Thus, our aim investigate prospective role MSP integration into nanomaterials (MSPNPs) underlying molecular mechanisms supporting application as alternative therapy IBD using a colitis rat model. To induce...

10.3390/pharmaceutics14061183 article EN cc-by Pharmaceutics 2022-05-31

The rate of chronic kidney disease (CKD) is increasing globally, and it caused by continuous damage to tissue. With time the renal becomes irreversible, leading CKD development. In females, post-menopause lack estrogen supply has been described as a risk factor for development, studies targeting are scarce. present study, we used exosomes isolated from bone marrow mesenchymal stem/stromal cells (BM-MSCs) test their therapeutic potential against development CKD. At first, menopause model was...

10.3390/biom12050663 article EN cc-by Biomolecules 2022-05-02

The current study aimed to evaluate the chemical, phytochemical, and sensory properties; nutritional value; antioxidant properties resulting from incorporation of yogurt fortified with aqueous extract Hawthorn leaves in Sprague Dawley rats. results revealed that containing exhibited no significant differences terms its protein, fat, ash contents compared control samples. Moreover, highest total phenolic content (62.00 ± 1.70) activity (20.60 0.74%) were detected 0.4% leaf other consumption...

10.3390/fermentation8050200 article EN cc-by Fermentation 2022-04-29

We aimed to evaluate the effectiveness of Highly Upregulated in Liver Cancer (HULC) and microRNA-372 (miR-372) as biochemical markers Hepatocellular carcinoma (HCC) HCV-infected patients.The present study was conducted on 100 Egyptian individuals divided into 3 groups, 40 patients with HCC HCV infection, only HCV-infected, 20 normal controls. They were subject full history taking, clinical laboratory examination, assessment HULC miR-372 levels by real-time PCR.A statistically significant...

10.29252/rbmb.9.2.230 article EN cc-by Reports of Biochemistry and Molecular Biology 2020-06-01

Hepatic ischemia/reperfusion (Hep I/R) is a great health burden during hepatic transplantation surgery. The present work aimed to examine the mitigative effect of Chlorella vulgaris against Hep I/R and its underlying protective mechanisms. animals in research were classified into four equal experimental groups (n=6): sham group, sham+Chlorella I/R+Chlorella group. ischemia results liver impairment, as evidenced by elevated enzyme levels altered histology. It also reduced antioxidant...

10.5115/acb.24.318 article EN Anatomy & Cell Biology 2025-04-23

Background:: Diabetic wound represents a serious issue with substantial impact and an exceptionally complex pathology affecting patients’ mental health quality of life. So, we have developed novel 3D organo-hydrogel nanocomposite polydopamine/TiO2 nanoparticles cu (PDA-TiO2@Cu) examined its efficacy in diabetic healing. Methods:: Forty-five adult male albino rats were divided into normal control (non-diabetic non-treated skin wounds), (diabetic organo-hydrogel-treated wounds treated...

10.2174/0118715303280532240415094718 article EN Endocrine Metabolic & Immune Disorders - Drug Targets 2024-04-26

The present study aimed to explore the epidemiologic threats and factors associated with coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) epidemic that emerged in Egypt during second COVID-19 wave. also diagnostic features role of surgical interventions CAM on outcome a central referral hospital. included 64 patients from hospital for similar number matched controls who did not develop CAM. most frequent among were use corticosteroids, older age, diabetes. presented facial...

10.3855/jidc.19897 article EN cc-by The Journal of Infection in Developing Countries 2024-12-31
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