- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Mesenchymal stem cell research
- Total Knee Arthroplasty Outcomes
- Sports injuries and prevention
- Lower Extremity Biomechanics and Pathologies
- Tendon Structure and Treatment
- Fibroblast Growth Factor Research
- Bone fractures and treatments
- Neurofibromatosis and Schwannoma Cases
- Head and Neck Surgical Oncology
- Hip disorders and treatments
- Folate and B Vitamins Research
- Meningioma and schwannoma management
Humanitas Castelli
2019-2023
Unidad de Cirugía Artroscópica
2019
Ospedale Sacro Cuore Don Calabria
2015-2018
Chondral lesions of the knee represent a challenge for orthopaedic surgeon. Several treatments have been proposed with variable success rate. Recently, new therapeutic approaches, such as use mesenchymal stem cells, shown promising results. The adipose tissue is good source these naturally occurring regenerative due to its abundance and easy access. In addition, it can be used provide cushioning filling structural defects. 1-year safety outcome single intra-articular injection autologous...
Conservative therapies for the treatment of knee degenerative processes are used before resorting to surgery; nonetheless, they may offer only short-term benefits. Encouraging preliminary results have been reported using mesenchymal stem cells (MSCs), either alone or in association with surgery. Among many sources, adipose tissue has created a huge interest, because its anti-inflammatory and regenerative properties ascribed stromal vascular fraction. We previously safety feasibility...
Abstract Purpose Among the conservative strategies to manage patients with symptomatic knee osteoarthritis (OA), an innovative approach exploiting regenerative capability of adipose tissue and its resident MSCs (Mesenchymal Stem Cells or Medicinal Signalling Cells) has been proposed encouraging results. This study aims demonstrate benefits autologous micro‐fragmented (MAT) injection in treatment whether any variables may affect outcome. is a case series single‐centre which underwent...
Osteoarthritis is a widespread pathology, with prevalence of over 50% the population, which leads to pain and functional limitation. At moment, no surgical technique has been shown be capable real regeneration chondral layer. The new regenerative frontier seems represented by self-ability Stromal Vascular Fraction (SVF) preserve cellular network, essential for cell regeneration. Several micro-fragmented adipose tissue extraction processing systems have refined in past years recent literature...