A5026337576- Systemic Sclerosis and Related Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Osteoarthritis Treatment and Mechanisms
- Inflammatory Myopathies and Dermatomyositis
- Magnesium in Health and Disease
- Shoulder Injury and Treatment
- Lower Extremity Biomechanics and Pathologies
- Musculoskeletal pain and rehabilitation
- Sports injuries and prevention
- Tendon Structure and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Pulmonary Hypertension Research and Treatments
- Dermatologic Treatments and Research
- Potassium and Related Disorders
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Rheumatoid Arthritis Research and Therapies
- Eosinophilic Disorders and Syndromes
- Musculoskeletal synovial abnormalities and treatments
- Orthopaedic implants and arthroplasty
- Parathyroid Disorders and Treatments
- Mast cells and histamine
- Sarcoidosis and Beryllium Toxicity Research
The University of Melbourne
2022-2025
St Vincent's Hospital
2022-2025
GTx (United States)
2024
St. Vincent's Hospital
2024
The Alfred Hospital
2015-2024
Monash Health
2023-2024
Saint Vincent's Catholic Medical Center
2024
St. Vincent's Birmingham
2024
Monash University
2014-2023
The Royal Melbourne Hospital
2021-2023
To quantify the frequency and clinical implications of systemic sclerosis (SSc)-associated left ventricular function (LV) impairment.
Objective To explore the effect of left ventricular (LV) diastolic dysfunction (LVDD) in systemic sclerosis (SSc)-associated interstitial lung disease (ILD), and to investigate SSc-specific associations clinical correlates LVDD. Methods There were 102 Australian Scleroderma Cohort Study participants with definite SSc radiographic ILD included. Diastolic function was classified as normal, indeterminate, or abnormal according 2016 American Society Echocardiography/European Association...
To determine the frequency, clinical correlates and implications of evidence muscle disease in systemic sclerosis (SSc). Australian Scleroderma Cohort Study participants with ≥1 creatine kinase (CK) proximal power assessment were subdivided according to presence weakness (PW: power<5/5) CK elevation(≥140IU/L). Participants assigned one four groups: concurrent PW&CK elevation, PW alone, elevation alone or neither. Between-group comparisons made chi-squared, ANOVA Kruskal-Wallis tests....
Abstract Objectives To quantify the frequency and impact of malnutrition in systemic sclerosis (SSc), as diagnosed by Global Leadership Initiative on Malnutrition (GLIM) criteria, based weight loss, BMI muscle atrophy. Methods Australian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc with ≥1 concurrent height measurement were included. The chi-squared test, two-sample t-test or Wilcoxon’s rank-sum test was used between-group comparison appropriate. Multivariable...
Objective The importance of early integration palliative care in the management complex multisystem diseases has been recognized. In this study, we aimed to quantify need for specialist patients with systemic sclerosis (SSc). Methods Using data from 875 enrolled Australian Scleroderma Cohort Study, defined as a high symptom burden at two or more consecutive study visits, ≥50% overall visit immediately before death. Symptoms interest included breathlessness, fatigue, pain, depression,...
Objective Our objective was to define the frequency and impact of multimorbidity in systemic sclerosis (SSc). Method Australian Scleroderma Cohort Study participants meeting American College Rheumatology/EULAR criteria were included. Charlson Comorbidity Index scores calculated at each visit, with defined as ≥4. Generalized estimating equations used model longitudinal data multivariable models including age, sex, subclass, interstitial lung disease, pulmonary arterial hypertension status....
Studies have proposed vastus medialis (VM) muscle cross-sectional area change as a variable associated with cartilage volume loss in knee osteoarthritis (OA). However, the VM also includes fat (%Fat), which may influence function. This study analyzed and %Fat data, separately combination, to predict symptoms, loss, bone marrow lesion (BML) OA.This included according-to-protocol population (n = 143) of 2-year OA randomized clinical trial having magnetic resonance imaging at baseline 2 years....
Abstract Objectives To describe the clinical phenotype and prognosis of people in Australian Scleroderma (SSc) Cohort Study with pulmonary arterial hypertension (PAH) or without interstitial lung disease (ILD). Methods Participants meeting ACR/EULAR criteria for SSc were divided into four mutually exclusive groups: those PAH (PAH-only), ILD (ILD-only), concurrent (PAH-ILD) neither nor (SSc-only). Logistic linear regression analyses used associations between features, health-related quality...
Patellar tendinopathy is a common cause of activity-related anterior knee pain. Evidence conflicting as to whether obesity risk factor for this condition. The aim study was determine the relationship between and prevalence magnetic resonance imaging (MRI) defined patellar in community-based adults.297 participants aged 50-79 years with no history pain or injury were recruited from an existing cohort. Measures included measured weight body mass index (BMI), self-reported at age 18-21 heaviest...
Objective To describe the clinical characteristics and outcomes of systemic sclerosis–mixed connective tissue disease (SSc–MCTD) SSc overlap syndrome. Methods We included patients from Australian Scleroderma Cohort Study who met American College Rheumatology/European Alliance Associations for Rheumatology criteria SSc. Three mutually exclusive groups were created: SSc–MCTD, overlap, only. Univariate comparison features was performed by analysis variance or chi‐square test. Survival using...