Christopher Langfield
A5055828430- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Photoreceptor and optogenetics research
- Neuroscience and Neural Engineering
- Electron and X-Ray Spectroscopy Techniques
- Advanced Neuroimaging Techniques and Applications
- Aging, Elder Care, and Social Issues
- Spatial Neglect and Hemispheric Dysfunction
- Advanced Electron Microscopy Techniques and Applications
- Pelvic floor disorders treatments
- Neural and Behavioral Psychology Studies
- Human Pose and Action Recognition
- Zebrafish Biomedical Research Applications
- Elder Abuse and Neglect
- Advanced Vision and Imaging
- Motor Control and Adaptation
- Functional Brain Connectivity Studies
- Magnetic Properties and Applications
Columbia University
2022-2025
Columbia University Irving Medical Center
2021-2023
Cold Spring Harbor Laboratory
2022
Princeton University
2022
Abstract Understanding brain function relies on the collective work of many labs generating reproducible results. However, reproducibility has not been systematically assessed within context electrophysiological recordings during cognitive behaviors. To address this, we formed a multi-lab collaboration using shared, open-source behavioral task and experimental apparatus. Experimenters in ten laboratories repeatedly targeted Neuropixels probes to same location (spanning secondary visual...
Understanding brain function relies on the collective work of many labs generating reproducible results. However, reproducibility has not been systematically assessed within context electrophysiological recordings during cognitive behaviors. To address this, we formed a multi-lab collaboration using shared, open-source behavioral task and experimental apparatus. Experimenters in ten laboratories repeatedly targeted Neuropixels probes to same location (spanning secondary visual areas,...
Understanding brain function relies on the collective work of many labs generating reproducible results. However, reproducibility has not been systematically assessed within context electrophysiological recordings during cognitive behaviors. To address this, we formed a multi-lab collaboration using shared, open-source behavioral task and experimental apparatus. Experimenters in ten laboratories repeatedly targeted Neuropixels probes to same location (spanning secondary visual areas,...
Introduction Aging negatively impacts the ability to rapidly and successfully switch between two or more tasks that have different rules objectives. However, previous work has shown context extent of this age-related impairment: while there is relative invariance when participants must back forth simple (often called “switch costs”), differences emerge contexts changes from one in which only task be performed multiple performed, but a trial-level not required (e.g., repeat trials within dual...
Understanding brain function relies on the collective work of many labs generating reproducible results. However, reproducibility has not been systematically assessed within context electrophysiological recordings during cognitive behaviors. To address this, we formed a multi-lab collaboration using shared, open-source behavioral task and experimental apparatus. Experimenters in ten laboratories repeatedly targeted Neuropixels probes to same location (spanning secondary visual areas,...
Abstract Financial decision‐making (FDM) and awareness of the integrity one's FDM abilities (or financial awareness) are both critical for preventing mistakes. We examined white matter correlates these constructs hypothesized that tracts connecting temporal–frontal regions would be most strongly correlated with awareness. Overall, 49 healthy older adults were included in analysis 44 analyses. The Objective Competency Assessment Inventory was used to measure FDM. measured by integrating...
An introduction to the mathematical problem of cryo-electron microscopy (cryo-EM) is given, along with an overview ASPIRE, open-source Python package for processing cryo-EM image data. ASPIRE uses unique Fourier basis representations images particles. The challenge representing these structures within codebase was addressed by building extensible class hierarchy using mixins.
Abstract Background Reduced awareness of one’s financial decision‐making abilities (financial awareness) can result in costly mistakes (e.g., forgetting to pay credit card dues) and increase vulnerability exploitation getting scammed). In cognitively healthy older adults, thinner right medial temporal cortex is associated with overconfidence abilities. However, it important examine other neuroimaging metrics create a comprehensive picture the links between brain adults. current study, we...
Abstract Background Aging research has repeatedly shown that crystallized abilities, cognitive processes reliant on learned knowledge, are well preserved into old age. On the other hand, fluid not knowledge‐dependent, show decline as early third decade of life. It is still unclear what mechanism enables two starkly contrasting aging trajectories to exist all within same brains. Method From Reference Ability Neural Network (RANN) study, 181 participants (age=51.2±17.2, 101females) with both...