A5029780355- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Environmental DNA in Biodiversity Studies
- Wildlife Ecology and Conservation
- Plant Pathogens and Fungal Diseases
- Drug Transport and Resistance Mechanisms
- Genetic and phenotypic traits in livestock
- Avian ecology and behavior
- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- Identification and Quantification in Food
- Musculoskeletal pain and rehabilitation
- Primate Behavior and Ecology
- Genetic and Environmental Crop Studies
- Digestive system and related health
- Mycotoxins in Agriculture and Food
- Plant and animal studies
- Animal Behavior and Reproduction
- Pharmacological Effects and Toxicity Studies
- Ecology and Vegetation Dynamics Studies
- Pharmacogenetics and Drug Metabolism
- Bacteriophages and microbial interactions
- Bacterial Identification and Susceptibility Testing
- Plant Pathogenic Bacteria Studies
University of the Free State
2023-2025
Princess Máxima Center
2024
National Health Laboratory Service
2022-2023
National Institute for Communicable Diseases
2022-2023
Respiratory and Meningeal Pathogens Research Unit
2023
South African National Biodiversity Institute
2019-2021
Stellenbosch University
2009-2020
University of the Western Cape
2014-2019
National Zoological Gardens of South Africa
2017-2019
University of Cape Town
2004-2017
Synthetic biology has grown exponentially in the last few years, with a variety of biological applications. One emerging applications synthetic is to exploit link between microorganisms, biologics, and human health. To this link, it critical select effective tools for use appropriate microorganisms that would address unmet needs health through development new game-changing by complementing existing technological capabilities. Lactic acid bacteria (LAB) are considered chassis organisms can be...
Fusarium head blight (FHB) is a major disease affecting wheat production worldwide, caused by multiple species. In this study, seven strains were isolated from fields across the Western Cape region of South Africa and identified through phylogenetic analysis. The classified into three species complexes: graminearum complex (FGSC), incarnatum-equiseti (FIESC), tricinctum (FTSC). Disease severity was highest in coast regions Swellendam (42.73%) Caledon (38.00%), with dough stage development...
This study used next generation sequencing to generate the mitogenomes of four African pangolin species; Temminck's ground (Smutsia temminckii), giant (S. gigantea), white-bellied (Phataginus tricuspis) and black-bellied (P. tetradactyla).The results indicate that pangolins are 16,558 bp for S. temminckii, 16,540 gigantea, 16,649 P. tetradactyla 16,565 tricuspis. Phylogenetic comparisons indicated two lineages with high posterior probabilities providing evidence support classification...
Purpose: A majority of genes associated with inherited retinal diseases (IRDs) have been identified in patients European origin. Indigenous African populations exhibit rich genomic diversity, and evaluation reported genetic mutations has yielded low returns so far. Our goal was to perform whole-exome sequencing (WES) examine variants known IRD underrepresented cohorts. Methods: Whole-exome performed on 56 samples from 16 families diverse phenotypes that had remained undiagnosed after...
Introduction A distinct strain of Klebsiella pneumoniae ( K. ) referred to as hypervirulent (hvKp) is associated with invasive infections such pyogenic liver abscess in young and healthy individuals. In South Africa, limited information about the prevalence virulence this hvKp available. The aim study was determine virulence-associated factors isolates from one largest tertiary hospitals a African province. Methods total 74 were received Pelonomi Tertiary Hospital National Health Laboratory...
Human organic cation transporter 1 is primarily expressed in hepatocytes and mediates the electrogenic transport of various endogenous exogenous compounds, including clinically important drugs. Genetic polymorphisms gene coding for human 1, SLC22A1, are increasingly being recognized as a possible mechanism explaining variable response to clinical drugs, which substrates this transporter. The genotypic allelic distributions 19 nonsynonymous one intronic SLC22A1 single nucleotide were...
Success of a metabarcoding study is determined by the extent taxonomic coverage and quality records available in DNA barcode reference database used. This aimed to create an rbcL trnL (UAA) sequence plant species that are potential herbivore foraging targets commonly found semi-arid savannas eastern South Africa. An area-specific list 765 was compiled according collection areas comparable African savanna. Thereafter, sequences from this were mined GenBank BOLD databases specific criteria...
Three species of Old World vultures on the Asian peninsula are slowly recovering from lethal consequences diclofenac. At present reason for sensitivity to diclofenac is unknown. Furthermore, it has since been demonstrated that other like Cape (Gyps coprotheres; CGV) and griffon (G. fulvus) also susceptible toxicity. Oddly, New Turkey vulture (Cathartes aura) pied crow (Corvus albus) not As a result latter, we postulate an evolutionary link first step in understanding susceptibility toxicity,...
Greater bushbabies, strepsirrhine primates, that are distributed across central, eastern and southern Africa, with northern South Africa representing the species' most southerly distribution. bushbabies habitat specialists whose naturally fragmented habitats getting even more due to anthropogenic activities. Currently, there is no population genetic data or study published on species. The aim of our was investigate variation in a thick-tailed bushbaby, Otolemur crassicaudatus, Soutpansberg...
Background: Fibromyalgia is considered to be a multifactorial condition in which number of biological and psychological variables interact. However, the exact pathogenesis effective treatment fibromyalgia are still unknown.In this study relationship between psychosocial self-efficacy, helplessness, perceived social support, pain-related beliefs several measures health status patients with were examined.Methods: Thirty-one diagnosed participated study. Patients concomitant rheumatological...