Pomegranate peels, which are normally processed as the main byproduct of pomegranate juice production, worthy being researched and utilized for aim economic environmental benefits. In a phytochemical investigation peels Punica granatum L., 10 phenolic compounds containing common hexahydroxy diphenol moiety were isolated. Three them identified first time named pomegranatins A-C, from other seven known ones, two obtained time. Their structures determined via extensive spectroscopic analysis....

Pomegranate flowers is an ancient medicine that has commonly been used to treat various diseases such as diabetes. However, no reports are available on the metabolic profile of pomegranate in vivo. In present study, with aid HPLC-Q-TOF-MS2, 67 compounds were identified extract, including 18 ellagitannins, 14 gallic acid and galloyl derivatives, five anthocyanins flavonoids. Seven firstly identified. vivo, 22 absorbed 35 metabolites rat biosamples (urine, feces, plasma tissues) after orally...

Liquid chromatography coupled to negative electrospray ionization (ESI) tandem mass spectrometry (MS/MS) employing a time‐of‐flight spectrometer was used in the structural determination of phenolic compounds and sesquiterpenoids occurring extract from Artemisia rupestris L. A total 91 including chlorogenic acid derivatives, flavonoids (aglycone, O ‐glycosyl, C ‐glycosyl C,O ‐glycosyl), 2‐phenoxychromones guaiane were identified by comparing retention time fragmentation behavior with...

Abstract Introduction Pomegranate ( Punica granatum L.) husk is a traditional herbal medicine abundant in phenolic compounds and plays some roles the treatment of oxidative stress, bacterial viral infection, diabetes mellitus, acute chronic inflammation. Objective Identification determination polyphenols macroporous resin pretreated pomegranate extract by high performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry (HPLC‐QTOF‐MS). Methods The total...

Abstract Introduction Mastic is a natural resin produced by Pistacia lentiscus L. (Anacardiaceae). The beneficial properties of this are attributed to its triterpenes and volatile compounds. Objective This study was conducted screen characterize the terpenes in mastic ethyl acetate extract (M‐Ex). Methods An ultrahigh‐performance liquid chromatography coupled quadrupole Orbitrap high‐resolution mass spectrometry (UHPLC‐Q‐Orbitrap‐HRMS) method developed for qualitative analysis M‐Ex. We...

Background: Kukeya tablets (KYs), a traditional ethnic medicine prescription, are widely used to treat migraines and eye ailments in China. Despite their extensive clinical use, current knowledge on therapeutic material basis is limited few major compounds, whereas certain minor ones have rarely been investigated. This study was conducted screen characterize the chemical components of KYs. Methods: A rapid effective UHPLC-Q-Orbitrap-HRMS method established. mass spectrometry qualitative...

Vitiligo is a stubborn multifactorial skin disease with prevalence of approximately 1% in the global population. Kaliziri, seeds Vernonia anthelmintica (L.) Willd., well-known traditional Uyghur medicine for treatment vitiligo. Kaliziri injections Chinese-marketed approved by China Food and Drug Administration The significant effects injection have been thoroughly studied. However, chemical components studies plasma quantification are lacking injection. Ultra-high-performance liquid...

A method based on ultra performance liquid chromatography with a diode array detector (UPLC-DAD) was developed for quantitative analysis of five active compounds and chemical fingerprint Rosa rugosa. Ten batches R. rugosa collected from different plantations in the Xinjiang region China were used to establish fingerprint. The feasibility advantages UPLC verified its similarity evaluation by systematically comparing chromatograms professional analytical software recommended State Food Drug...

An integrated strategy was developed for the systematic chemical fingerprint and chemometrics analysis quality assessment of Aloe vera (L.) Burm. f. The ultra-performance liquid chromatography established, all common peaks were tentatively identified by using ultra-high-performance hyphenated with quadrupole-orbitrap-high-resolution mass spectrometry. Afterwards, datasets subjected to hierarchical cluster analysis, principal component partial least squares discriminant holistically compare...

A simple and effective method employing LC-ESI-QTOF-MS was established for the qualitative analysis of chemical constituents in<italic>Neopicrorhiza scrphulariiflora</italic>roots.

Agarikon pill (AGKP), a traditional Chinese herbal formula, and has been used for chronic obstructive pulmonary disease (COPD) treatment clinically. However, the active components exact pharmacological mechanisms are still unclear. We aimed to investigate therapeutic effects of AGKP on COPD identify chemical constituents compounds. The were identified by ultrahigh-performance liquid chromatography coupled with quadrupole/orbitrap high-resolution mass spectrometry (UHPLC-Q-Orbitrap-HRMS)....

High performance liquid chromatography coupled with electrospray ionization quadrupole-time-of-flight tandem mass spectrometry was used to profile the phenylethanoid glycosides in Lagotis brevituba. A total of twenty-three were characterized by comparing retention time and fragmentation standards, accurate measurements, at low high collision energies. Most reported L. brevituba for first time. This established method may be employed comprehensive quality control

The hydrogenation of 4-nitrophenol (4-NP) has attracted much attention, since it is typically used as a model reaction for evaluating newly developed catalysts, but its mechanism still debated. Herein, Co(OH)2-modified CuO catalyst (Co(OH)2/CuO) was the reduction 4-NP to 4-aminophenol (4-AP) in an aqueous sodium borohydride (NaBH4) solution. investigated by UV-Vis spectroscopy (UV-Vis), high-performance liquid chromatography (HPLC), HPLC-Q-orbitrap high-resolution mass spectrometry...

The Shabyar tablet is commonly used as a traditional ethnic medicine prescription for the treatment of night blindness, poor vision, and headaches. However, chemical components have not been holistically explored, which seriously hinders discovery activity. This study qualitatively quantitatively investigated overall profile using ultra-high-performance liquid chromatography hyphenated with quadrupole-orbitrap high-resolution mass spectrometry. Altogether, 170 components, including 59...

Abstract Introduction Fungal species are an attractive resource for physiologically functional food and drug precursor. Fomes officinalis Ames, a medicinal fungus, is traditionally used as folk medicine in traditional Chinese prescription the therapy of cough asthma. The water‐soluble substances herbal medicines likely to play important physiological function. However, information on probing identifying chemical components aqueous extract Ames (AFO) remains unknown. Objective This study was...

By merging a high-performance liquid chromatography diode array detector (HPLC-DAD) method with thin-layer (HPTLC), an assay was developed for chemical fingerprinting and quantitative analysis of traditional medicine Majun Mupakhi ELA (MME), constituent compounds were identified using HPLC coupled UHPLC-DAD-Quadrupole-Orbitrap-MS method. In addition, the antioxidant capacity MME assessed based on ability components to scavenge radicals in vitro Using HPLC-DAD HPTLC easily validated results...

This work aimed to develop and evaluate a post-acquisition data processing strategy, referred as mass defect filter (MDF), for rapid target the resin glycosides in root of Convolvulus scammonia by setting rang range from high-resolution MS data. The full-scan were acquired high-performance liquid chromatography coupled with Q Exactive Plus hybrid quadrupole-orbitrap spectrometer that featured high resolution, accuracy, sensitivity. To screen glycosides, three parent m/z 871, 853, 869...