A5102920401- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Ocular Infections and Treatments
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Antifungal resistance and susceptibility
- Retinal Imaging and Analysis
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Ocular Surface and Contact Lens
- Neurological Disorders and Treatments
- Flavonoids in Medical Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Multiple Myeloma Research and Treatments
- Facial Trauma and Fracture Management
- Facial Rejuvenation and Surgery Techniques
- Traumatic Ocular and Foreign Body Injuries
- Ophthalmology and Eye Disorders
- Retinal and Macular Surgery
- Ocular Oncology and Treatments
- Ocular Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Diabetes Treatment and Management
- Nasolacrimal Duct Obstruction Treatments
- Cerebral Venous Sinus Thrombosis
Taichung Veterans General Hospital
2006-2019
National Tsing Hua University
2014
Overseas Chinese University
2006-2007
This population-based, retrospective cohort study was to investigate whether metformin is associated with a lower risk of subsequent age-related macular degeneration (AMD) in patients type 2 diabetes.Using the Taiwan National Health Insurance Research Database from 2001 2013, 68205 subjects diabetes were enrolled cohort. Among them, 45524 users and 22681 nonusers. The nonmetformin groups followed until end 2013. Cox regression analyses used estimate hazard ratios (HRs) for AMD development...
Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits.Intravitreal injections 35 microg/0.1 mL were administered to rabbits. Vitreous and aqueous humor levels determined at selected time intervals (1, 2, 4, 8, 16, 24, 48 hours), vitreous half-life was calculated. Four six eyes per point enucleated immediately stored -80 degrees C. Aqueous samples withdrawn before enucleation, obtained from ocular dissection isolation various intervals....
Previous cross-sectional studies revealed a higher prevalence of depression among glaucoma patients. However, cohort were in lack to build the risk incident after diagnosis glaucoma. The aim our study was investigate association between and subsequent developing assess factors associated with A population-based retrospective using Taiwan National Health Insurance Research Database conducted from January 1, 2001 through December 31, 2011. Glaucoma patients (n = 8777) age- gender-matched...
To investigate a possible association between normal tension glaucoma (NTG) and an increased risk of developing Alzheimer's disease (AD).Retrospective cohort study.NTG group the comparison were retrieved from whole population Taiwan National Health Insurance Research Database 1 January 2001 to 31 December 2013.A total 15 317 subjects with NTG enrolled in group, 61 268 age-matched gender-matched without group.Kaplan-Meier curves generated compare cumulative hazard AD two groups. A...
Caspofungin exhibits potent antifungal activities against Candida and Aspergillus species. The elimination rate retinal toxicity of caspofungin were determined in this study to assess its pharmacokinetics safety the treatment fungal endophthalmitis. Intravitreal injections 50 μg/0.1 ml administered rabbits. Levels vitreous aqueous humors using high-performance liquid chromatography (HPLC) at selected time intervals (10 min 1, 2, 4, 8, 16, 24, 48 h), half-lives calculated. Eyes intravitreally...
Purpose . To investigate whether the risk of subsequent stroke, ischemic hemorrhagic and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods From entire population Taiwan National Health Insurance Research Database (NHIRD) from 2001 2013, a total 22919 subjects with RVO were enrolled in group, 114595 propensity score (PS)-matched non-RVOs comparison group. PS matching was based on age, gender, obesity, diabetes, hypertension,...
To report the epidemiological and clinical data as well surgical outcomes of canalicular lacerations with Mini-Monoka insertion at a tertiary center in Taiwan to discuss differences traumatic pattern, pathogenesis, between other countries.From 2009 2018, all 48 patients who underwent laceration repair stent were retrospectively analyzed. Demographic recorded.The mean age was 38 years. Single lower canaliculus involved 37 (77.1%) patients, upper 10 (20.8%) both 1 (2.1%) patient. The most...
To investigate the penetration of topical 1% voriconazole through cornea into aqueous humor in New Zealand white rabbits and to determine effect mechanical scraping corneal epithelium.The right eyes 29 were maintained with epithelium intact, left underwent debridement central 7.5 mm cornea. A loading dose consisted a drop applied every 5 min for initial half hour followed by maintenance consisting 20 min, which was about 2 hr. Then, first sample obtained after seven doses (loading dose)...
Purpose: The aim of this study was to investigate the relationship between pterygium and a decrease in corneal endothelial cell density (ECD) patients with unilateral primary pterygium. Methods: In retrospective cross-sectional study, 90 consecutive were enrolled from January 2010 June 2012. Corneal ECD measured both eyes, fellow eyes considered as controls. percentage cornea analyzed. An increase astigmatism evaluated for association decreased using Pearson correlation test. Results: ranged...
PURPOSE: To assess whether toxic chemicals produced during autoclaving sterilization were 1 of the main causes diffuse lamellar keratitis (DLK) and to analyze clinical outcomes patients developing DLK after laser in situ keratomileusis (LASIK) treated with intensive topical corticosteroids. SETTING: Department Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic China. METHODS: A total 14 eyes 7 received technically smooth LASIK developed DLK, including 6 severe 8...
Whether carotid artery stenosis (CAS) is an independent risk factor for open-angle glaucoma remains unclear. In this study, we investigated the association between CAS and development of in Taiwanese population-based cohort derived from a longitudinal database containing claims data Taiwan National Health Insurance (NHI) program; study enrolled 2093 patients with 8372 without matched by age sex 1999 to 2010. Diagnoses (OAG) were identified during follow-up period lasting through December 31,...