A5015026738- 3D Printing in Biomedical Research
- Cancer Cells and Metastasis
- Bladder and Urothelial Cancer Treatments
- Glutathione Transferases and Polymorphisms
- Ferroptosis and cancer prognosis
- Microfluidic and Bio-sensing Technologies
- Cancer Genomics and Diagnostics
Zhongnan Hospital of Wuhan University
2022-2023
Wuhan University
2022-2023
Capital Medical University
2022
Beijing Friendship Hospital
2022
Abstract Patient personalized treatment models can predict response and assist in determining the optimal option for individual patients. The tumor microenvironment mediates development prognosis. However, current such as patient‐derived xenograft (PDX) 2D culture fail to preserve microenvironment. Herein, a technique acoustic‐droplet‐printing‐of‐patient‐derived‐organoids (ADPDOs) is reported, which allows high‐throughput, high‐viability, rapid, uniform printing preparation of organoids. In...
Abstract Background: Tobacco-smoking is a known risk factor for bladder cancer (BCa). However, typical tobacco-smoking induced mutation signature, COSMIC SBS4, established in lung and head-and-neck cancer, has not yet been virtually found BCa. Methods: De novo signature extraction was performed. Association of SBS4-like with clinicopathologic molecular features were analyzed statistical bioinformatics analysis. The role AHR/CYP1A BaP-induced carcinogenic effects functionally investigated RT4...