- Obesity, Physical Activity, Diet
- Cerebral Palsy and Movement Disorders
- Physical Activity and Health
- Liver Disease Diagnosis and Treatment
- Cardiovascular and exercise physiology
- Children's Physical and Motor Development
- Balance, Gait, and Falls Prevention
- Electromagnetic Fields and Biological Effects
- Cardiac Health and Mental Health
- Musculoskeletal pain and rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Infant Development and Preterm Care
- Hemophilia Treatment and Research
- Heart Rate Variability and Autonomic Control
- Sports injuries and prevention
- Spine and Intervertebral Disc Pathology
- Nutrition and Health in Aging
- Liver Disease and Transplantation
- Occupational Health and Performance
- Cardiovascular Health and Disease Prevention
- Microbial Inactivation Methods
- Bladder and Urothelial Cancer Treatments
- HIV-related health complications and treatments
- Childhood Cancer Survivors' Quality of Life
- Adolescent and Pediatric Healthcare
University of Michigan
2023-2024
Trinity College Dublin
2014-2023
St. James's Hospital
2004-2023
Tallaght University Hospital
2003-2004
University of Ulster
1993
Loughborough University
1968
Objective: To investigate the relationships between time spent in specific intensities of activity and inactivity, cardiorespiratory fitness body composition children. Methods: A cross-sectional study was conducted a random sample schools. Height, weight waist circumference were measured 224 children aged 7–10 years. Cardiorespiratory estimated by 20 m multistage running test, physical over 4 days RT3 (a triaxial accelerometer). Time each day moderate vigorous calculated. Results: Twelve...
Summary Background Lifestyle interventions are the primary treatment for metabolic (dysfunction) associated fatty liver disease (MAFLD). However, histological and cardiometabolic effects of aerobic exercise in MAFLD remain unclear. Aims To assess a 12‐week intervention on endpoints MAFLD. Methods Patients with biopsy‐confirmed participated intervention. Liver histology, cardiorespiratory fitness (estimated V̇O 2max ), physical activity, anthropometry biochemical markers were assessed at...
An attempt has been made to estimate the number of living people with skeletal dysplasias (osteochondrodysplasias) in Scotland, England and Wales, ascertained through five orthopaedic centres different parts Britain. Index patients their affected relatives were sought reassessed. Over 30-year period between 1950 1979 inclusive a minimum prevalence was calculated (excluding stillbirths, perinatal deaths, chromosome anomalies, metabolic bone disease short stature per se). The results indicate...
In this study, the injury incidence and association with type volume of training in international rowers were described.A prospective cohort design was used over a 12-month period.20 who competing as part Irish Amateur Rowing Union squad system.The interviewed monthly, data collected regarding their competition exposure well experience.A mean rate 3.67 per 1000 hours reported total 44 injuries period. The number sustained athlete 2.2 (1.24) area where greatest lumbar spine (31.82% injuries,...
Adults with cerebral palsy (CP) are known to participate in reduced levels of total physical activity. There is no information available however, regarding moderate-to-vigorous activity (MVPA) this population. Reduced participation MVPA associated several cardiometabolic risk factors. The purpose study was firstly compare sedentary, light, and adults CP without CP. Secondly, the objective investigate association between components, sedentary behavior factors (n=41) age 18-62 yr (mean ±...
Reduced participation in physical activity and increased time spent sedentary behavior are associated with overweight, chronic disease, disability. In order to optimize recommendations interventions increase reduce children cerebral palsy (CP), knowledge of their is needed.The aim this study was describe light, moderate, vigorous preadolescent without CP compare between the 2 groups.This a cross-sectional 33 children, aged 6 10 years, (Gross Motor Function Classification System [GMFCS]...
Physical activity has beneficial effects on arterial stiffness among healthy adults. There is a lack of data this relationship in adults with hypertension. The majority studies which have examined physical and used subjective measures activity. aim study was to investigate the between objectively measured habitual individuals newly diagnosed essential hypertension.Adults attending an outpatient hypertension clinic were recruited into cross sectional study. using triaxial accelerometer. Pulse...
Abstract A simultaneous recording of the electrical activity some superficial muscles trunk, arm and thigh was made during performance single knee circle mount on horizontal bar. Changes in pattern revealed by recorded electromyograms ( E.M.G.) two twelve-year-old schoolboys a three-month period while exercise learned were studied compared with trained gymnast. The E.M.G. fluent gymnast showed co-ordinated between hip-knee arm-shoulder ones. At early stages practice long duration high bursts...
To report the prevalence of cardiometabolic risk factors in a cohort adults with cerebral palsy (CP) and to investigate ability anthropometric measures predict these factors.Cross-sectional study.Testing took place laboratory setting.Adults CP (N=55; mean age, 37.5±13.3 y; Gross Motor Function Classification System levels, I-V) participated this study.Not applicable.Total cholesterol, high-density lipoprotein low-density triglycerides, glucose, insulin, C-reactive protein levels were...
Background Children with cerebral palsy (CP) participate in reduced levels of physical activity and spend increased time sedentary behavior. The effect behavior on their cardiometabolic health has not been investigated. Objectives purposes this study were: (1) to investigate the prevalence overweight/obesity elevated blood pressure (BP) among a cohort ambulatory children CP (2) associations activity, behavior, overweight/obesity, BP CP. Study Design This was cross-sectional 90 children, aged...
Exercise increases wellbeing and improves mood. It is however unclear how these mood changes relate to brain function. We conducted a randomized controlled trial investigating resting-state modifications in healthy adults after an extended period of aerobic physical exercise their relationship with improvements. aimed identify novel functional networks whose activity could provide physiological counterpart the mood-related benefits exercise. Thirty-eight sedentary volunteers were randomised...
High levels of cardiovascular fitness and physical activity are associated with higher cognitive function in people HIV, thus, they may reduce the risk developing HIV-associated neurocognitive disorder (HAND). This study aimed to investigate effects a 16-week aerobic exercise intervention on HIV. Eleven participants living HIV were recruited into study. Participants randomised either an group (n = 5), that completed programme training, 3 times per week (2 supervised sessions one unsupervised...
Short-wave diathermy (SWD) is widely available, yet a comprehensive examination of current clinical practice remains absent from the literature. The present paper aims to assess and safety issues in continuous (CSWD) pulsed (PSWD) short-wave application subsequently indicate areas for future research.A postal survey was carried out among 116 senior physiotherapists 41 Irish hospital-based physiotherapy departments.The response rate study 75%. Analysis found that PSWD preferred mode treatment...
Lumbar spine injury in rowers is common and ergometer rowing has been cited as a risk factor for this injury. The purpose of study to compare lumbar kinematics between single scull examine the effect fatigue on kinematics. sagittal motion 19 elite male (lumbar free previous six months) was measured with an electrogoniometer during ‘step test’ sculling boat. Maximum range flexion recorded standing reference. Power output heart rate were tests. Heart used surrogate power test. increased step...
Mucosal-associated invariant T (MAIT) cells promote inflammation in obesity and are implicated the progression of non-alcoholic fatty liver disease (NAFLD). However, as intrahepatic MAIT cell response to lifestyle intervention NAFLD has not been investigated, this work aimed examine circulating populations patients with NAFLD, after either 12 weeks dietary (DI) or aerobic exercise (EI).Multicolour flow cytometry was used immunophenotype measure expression (median fluorescence intensity, MFI)...
Previous studies have reported marked interindividual variation in factor VIII (FVIII) clearance patients with hemophilia (PWH) and proposed a number of factors that influence this heterogeneity.To investigate the importance rates endogenous von Willebrand (VWF) compared those other FVIII half-life modifiers adult PWH.The recombinant was determined cohort 61 PWH. A range assessed (including plasma VWF:antigen VWF propeptide levels; VWF-FVIII binding capacity; ABO blood group; nonneutralizing...
The application of active video games (AVGs) during cardiac rehabilitation (CR) sessions could potentially facilitate patient adherence. feasibility, safety, and efficacy in-class AVG supplementation as an alternative to conventional phase 2 programs were investigated.A pilot, evaluator-blinded, intention-to-treat, randomized controlled trial recruited 32 low-moderate risk CR participants allocated them or AVG-supplemented exercise. Both groups experienced equal exercise loads for 6 weeks....
Background Children with cerebral palsy (CP) have poor cardiorespiratory fitness in comparison to their peers typical development, which may be due low levels of physical activity. Poor contribute increased cardiometabolic risk. Purpose The aim this study was determine the association between sedentary behaviour, activity and children CP. An objective fitness, anthropometric measures blood pressure Methods This included 55 ambulatory CP [mean (SD) age 11.3 (0.2) yr, range 6-17 yr; Gross...
Adults with long COVID often report intolerance to exercise. Cardiopulmonary exercise testing (CPET) has been used in many settings measure ability but conducted a few cohorts. We CPET sample of adults reporting symptoms using submaximal cycle ergometer protocol. studied pre-exercise predictors achieving 85% the age-predicted maximum heart rate (85%HRmax) logistic regression. Eighty participants were included (mean age 46 years, range 25−78, 71% women). Forty (50%) did not reach 85%HRmax. On...
Accurate survival prediction for bladder cancer patients who have undergone radical cystectomy can improve their treatment management. However, the existing predictive models do not take advantage of both clinical and radiological imaging data. This study aimed to fill this gap by developing an approach that leverages strengths (C), radiomics (R), deep-learning (D) descriptors prediction. The dataset comprised 163 patients, including clinical, histopathological information, CT urography...