About
Contact & Profiles
A5014561128
Research Areas
- Phytase and its Applications
- Bone health and treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Protein Kinase Regulation and GTPase Signaling
- Cellular transport and secretion
- Enzyme Production and Characterization
- Adenosine and Purinergic Signaling
- Organophosphorus compounds synthesis
- SARS-CoV-2 and COVID-19 Research
- Endoplasmic Reticulum Stress and Disease
- interferon and immune responses
- Enzyme Structure and Function
Consejo Superior de Investigaciones Científicas
2024
Instituto de Química Física Blas Cabrera
2021
The yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase DDP1 is a Nudix enzyme with pyrophosphatase activity on diphosphoinositides, dinucleotides, polyphosphates. These substrates bind to diverse protein targets participate in signaling metabolism, being essential for energy phosphate homeostasis, ATPase pump regulation, or phosphorylation. An exhaustive structural study of complex multiple ligands related its three substrate classes reported. This allowed full...
10.1126/sciadv.abf6744
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EN
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Science Advances
2021-04-23
D-myo-inositol 1,4,5-trisphosphate (InsP
10.1038/s41467-024-45917-5
article
EN
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Nature Communications
2024-02-19
10.1016/j.str.2024.10.025
article
EN
Structure
2024-11-01
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