Paper fibers allow the high dispersion of a fluorescent polythiophene chemosensor for suppression aggregation-induced quenching, which is applied to solid-state quantitative sensing metal ions using imaging analysis and pattern recognition techniques.

Organic thin-film transistors (OTFTs) have attracted intense attention as promising electronic devices owing to their various applications such rollable active-matrix displays, flexible nonvolatile memories, and radiofrequency identification (RFID) tags. To further broaden the scope of application OTFTs, we focus on host–guest chemistry combined with devices. Extended-gate types OTFTs functionalized artificial receptors were fabricated achieve chemical sensing targets in complete aqueous...

Simple, rapid, and accurate detection methods for saccharides are potentially applicable to various fields such as clinical food chemistry. However, the practical applications of on-site analytical still limited. To this end, herein, we propose a 96-well microtiter plate made paper paper-based chemosensor array device (PCSAD) simultaneous classification 12 quantification fructose glucose among saccharides. The mechanism saccharide relied on an indicator displacement assay (IDA) PCSAD using...

Given the fact that increase of attention to health monitoring in daily life, development an easy-to-handle sensor device is desirable. In this regard, appropriate design for highly selective detection a specific biomarker human samples required obtain accurate analytical results. Hence, we report extend-gate-type organic field-effect transistor (OFET)-based biosensor functionalized with laccase-linked mediator dopamine urine. mechanism, oxidation by laccase (i.e., N-ethylphenazonium moiety)...

The detection of mercury(<sc>ii</sc>) ions (Hg²⁺) in water was successfully achieved by a disposable and reusable extended-gate organic transistor modified with an artificial receptor.

We propose a novel strategy for high-throughput sensing of metal ions using molecular self-assembled colourimetric chemosensor array. The proposed assay has been achieved by only the combination commercially available materials. Importantly, easy-to-prepare can be utilised to quantitatively detect under competitive conditions.

Although the determination of oxyanions due to correlation with metabolic processes and diseases is in high demand, most developed methods are suffering from a shortage capability on-site analysis, sensitivity, user-friendliness. This paper introduces first colorimetric chemosensor array targeting various anions including glyphosate. The proposed sensor benefits some notable features such as utilizing only commercially available reagents, recognizing similarly structured compounds by...

Abstract Porous microneedles are expected to have a variety of potential for applications in diagnostics owing their ability penetrate human skin painlessly and extract bio‐fluid by capillary action. In this paper, ‘Porous Microneedle on Paper substrate’ (PMP) is proposed as novel platform direct integration sensors. A microneedle array with height approximately 840 μm was prepared paper. The fabrication process consists salt leaching heat press moulding. method, the particles utilized...

The current work proposes a novel method for accurate pattern recognition of (mono- and di-) amines determination enantiomeric excess (ee) using molecular self-assembly.

We herein report the quantitative detection of biogenic amines using a gold nanoparticle-based colorimetric chemosensor array for food analysis. The nanoparticles are functionalized with carboxylate derivatives, which capture target through hydrogen bonds and electrostatic interactions. simultaneous discrimination 10 amine derivatives was achieved by linear discriminant analysis 100% correct classification based on multi-colorimetric response pattern structural differences. Furthermore, real...

Abstract There is a growing interest in achieving sensor systems to enable on‐site testing of biomarkers. Herein, new strategy for highly sensitive protein detection at sub‐femtomolar levels without any labelling has been demonstrated by using an organic field‐effect transistor (OFET). An artificial histidine‐rich receptor (Ni II ‐nitrilotriacetic acid complex, Ni ‐nta) functionalizes portion (i.e. extended‐gate electrode) the fabricated OFET device. The responds electrically and selectively...

We herein report an organic field-effect transistor (OFET) based chemical sensor for multi-oxyanion detection with pattern recognition techniques. The oxyanions ubiquitously play versatile roles in biological systems, and accessing the information they provide would potentially facilitate fundamental research diagnosis pharmacology. In this regard, phosphates human blood serum be a promising indicator early case of significant diseases. Thus, development easy-to-use qualitative quantitative...

We herein report an organic transistor functionalized with a phenylboronic acid derivative and graphene oxide for the quantification of plasma glucose levels, which has been achieved by minimization interferent effects derived from physical protein adsorption on detection electrode.

Chemical modification of self-assembled monolayers (SAMs) at the solid-liquid interface can effectively impart SAMs with desired functions on demand. However, appropriate methods to monitor organic reactions have not yet been established. Therefore, this perspective introduces an extended-gate type field-effect transistor (EG-OFET)-based detector chemical between electrode OFET and aqueous solution containing reactants. The EG-OFET is operated by applying gate voltages, enabling monitoring...

Abstract Background Leucine-rich repeat kinase 2 (LRRK2) is the gene responsible for autosomal-dominant Parkinson’s disease (PD), PARK8, but mechanism by which LRRK2 mutations cause neuronal dysfunction remains unknown. In present study, we investigated first time a transgenic (TG) mouse strain expressing human with an I2020T mutation in domain, had been detected patients of original PARK8 family. Results The TG expressed dopaminergic (DA) neurons substantia nigra, ventral tegmental area,...

An ultra-low voltage operatable thin-film transistor based on a polythiophene pendant with carboxy sidechain can detect biogenic amines in water.

We believe that "the simpler we are, the more complete become" is a key concept of chemical sensing systems. In this work, "turn-on" fluorescence chemosensor array relying on only two self-assembled molecular chemosensors with ability both qualitative and quantitative detection phosphorylated saccharides has been developed. The easy-to-prepare was fabricated by in situ mixing off-the-shelf reagents (esculetin, 4-methylesculetin, 3-nitrophenylboronic acid). fluorescence-based saccharide...

Herein, we report on the fabrication of an extended-gated organic field-effect transistor (OFET)-based immunosensor and its application in detection human chromogranin A (hCgA). The fabricated OFET device possesses extended-gate electrode immobilized with anti-CgA antibody. titration results hCgA showed that electrical changes characteristics corresponded to glycoprotein recognition ability monoclonal antibody (anti-CgA). observed sensitivity (detection limit: 0.11 µg/mL) selectivity...