A5082659071- Neurogenesis and neuroplasticity mechanisms
- Childhood Cancer Survivors' Quality of Life
- Neuroinflammation and Neurodegeneration Mechanisms
- Family Support in Illness
- Single-cell and spatial transcriptomics
- CRISPR and Genetic Engineering
- Cancer Cells and Metastasis
- Pluripotent Stem Cells Research
- Anesthesia and Neurotoxicity Research
University of Basel
2021-2023
University of Zurich
2017
Adult neural stem cells (NSCs) contribute to lifelong brain plasticity. In the adult mouse ventricular-subventricular zone, NSCs are heterogeneous and, depending on their location in niche, give rise different subtypes of olfactory bulb (OB) interneurons. Here, we show that multiple regionally distinct NSCs, including domains usually quiescent, recruited gestation days during pregnancy. Synchronized activation these NSC pools generates transient waves short-lived OB interneurons, especially...
Abstract Neural stem cells (NSCs) in the adult mouse brain contribute to lifelong plasticity. NSCs ventricular-subventricular zone (V-SVZ) are heterogeneous and, depending on their location niche, give rise different subtypes of olfactory bulb interneurons. Here, we show that during pregnancy multiple regionally-distinct dynamically recruited at times. Coordinated temporal activation these NSC pools generates sequential waves short-lived interneuron mature mother around birth and perinatal...