A5030738005- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Pharmaceutical Practices and Patient Outcomes
- Venous Thromboembolism Diagnosis and Management
- Clinical practice guidelines implementation
- Atrial Fibrillation Management and Outcomes
- Stroke Rehabilitation and Recovery
- Antiplatelet Therapy and Cardiovascular Diseases
- Ocular Infections and Treatments
- S100 Proteins and Annexins
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Disease Prevention
- Healthcare Systems and Practices
- Trauma and Emergency Care Studies
- Antibiotic Use and Resistance
- Dementia and Cognitive Impairment Research
- Pharmacy and Medical Practices
- Intensive Care Unit Cognitive Disorders
- Bacterial Identification and Susceptibility Testing
- Cardiac Imaging and Diagnostics
University of Newcastle Australia
2012-2021
Hunter Medical Research Institute
2008-2020
John Hunter Hospital
2008-2020
Cliniques Universitaires Saint-Luc
2015
The George Institute for Global Health
2015
Westmead Hospital
2015
Ospedale Sacro Cuore Don Calabria
2015
Salford Royal NHS Foundation Trust
2015
Danderyds sjukhus
2015
The University of Sydney
2015
Objective: To assess the effectiveness of PAST (Pre-hospital Acute Stroke Triage) protocol in reducing pre-hospital and emergency department (ED) delays to patients receiving organised acute stroke care, thereby increasing access thrombolytic therapy. Design: Prospective cohort study using historical controls. Setting: Hunter Region New South Wales, September 2005 March 2006 (pre-intervention) 2007 (post-intervention). Participants: Consecutive presenting with a regional, tertiary referral...
Background Cerebral autoregulation can be impaired after ischemic stroke, with potential adverse effects on cerebral blood flow during early rehabilitation. Objective The objective of this study was to assess changes in velocity orthostatic variation at 24 hours stroke. Design This investigation an observational comparing mean velocities (MFVs) 30, 15, and 0 degrees elevation the head bed (HOB). Methods Eight participants underwent bilateral middle artery (MCA) transcranial Doppler...
Access to intravenous thrombolysis for acute ischaemic stroke is limited worldwide, particularly in regional and rural areas including Australia. We are testing the effectiveness of a new Prehospital Acute Stroke Triage protocol that includes prehospital assessment rapid transport patients from catchment major centre Newcastle, NSW, The local district hospitals within do not have capability or infrastructure deliver thrombolysis. trial has relevance clinicians, health service managers...
ABSTRACT INTRODUCTION Over-prescription of antibiotics for common infective conditions is an important health issue. Infective conjunctivitis represents one the most eye-related complaints in general practice. Despite its self-limiting nature, there evidence frequent practitioner (GP) antibiotic prescribing this condition, which inconsistent with evidence-based guidelines. AIM To investigate prevalence and associations GP registrars’ (trainees’) prescription conjunctivitis. METHODS We...
Background: Cognitive impairment following a minor stroke or transient ischemic attack (TIA) is common; however, due to diagnostic difficulties, the prevalence and underlying cause of remain poorly defined. We compared cognition in patients after stroke, TIA, mimic event at three time points first year event. examine whether cognitive occurs these events this differs based on type. Further, we measure findings persist controlling for age, education, presence vascular risk factors factors,...
Transient ischaemic attacks (TIA) and minor strokes (TIAMS) have the same pathophysiological mechanism as stroke carry a high risk of recurrent events. Diagnosis TIAMS can be challenging often occurs in general practice. Absolute cardiovascular (ACVR) is recommended basis for vascular management. Consideration diagnosis has been but its utility not established. Firstly, to document ACVR patients with incident TIAMS-mimics. Secondly, evaluate calculation informing initial TIAMS. The...
Introduction Anterior cerebral artery flow diversion, measured by transcranial Doppler ultrasound, is correlated with leptomeningeal collateral on digital subtraction angiography in the setting of middle occlusion. We aimed to assess influence diversion as a marker collateralization infarct size and penumbral volume. Methods assessed consecutive patients presenting within six-hours ischaemic stroke. defined ipsilateral mean velocity at least 30% greater than contralateral artery, was used...
Rationale Rapid response by health-care systems for transient ischemic attack and minor stroke (TIA/mS) is recommended to maximize the impact of secondary prevention strategies. The applicability this evidence Australian non-hospital-based TIA/mS management uncertain. Aims Within an community setting we seek document processes care, establish determinants access rates recurrent vascular events other clinical outcomes, performance ABC2-risk stratification, compare care outcomes those in UK...
Background: Transient ischemic attack (TIA) and minor stroke (TIAMS) are risk factors for recurrence. Some TIAMS may be preventable by appropriate primary prevention. We aimed to recruit "possible-TIAMS" patients in the INternational comparison of Systems care patient outcomes In Stroke TIA (INSIST) study. Methods: A prospective inception cohort study performed across 16 Hunter–Manning region, Australia, general practices catchment one secondary-care acute neurovascular clinic....