A5037987358- Astro and Planetary Science
- Mass Spectrometry Techniques and Applications
- Solar and Space Plasma Dynamics
- Ion-surface interactions and analysis
- CCD and CMOS Imaging Sensors
- Planetary Science and Exploration
- Ionosphere and magnetosphere dynamics
- Spacecraft Dynamics and Control
- Analytical Chemistry and Chromatography
- Laser-induced spectroscopy and plasma
- Magnetic confinement fusion research
- Thin-Film Transistor Technologies
- Atomic and Molecular Physics
- Nuclear Physics and Applications
- Dust and Plasma Wave Phenomena
- Space Science and Extraterrestrial Life
- Fluid Dynamics and Turbulent Flows
- Isotope Analysis in Ecology
- Metabolomics and Mass Spectrometry Studies
- Plasma Diagnostics and Applications
- Advanced Memory and Neural Computing
- Infrared Target Detection Methodologies
- Laser-Matter Interactions and Applications
- Analytical chemistry methods development
- Terahertz technology and applications
RIKEN Center for Biosystems Dynamics Research
2022-2024
Ube Frontier University
2022-2024
Osaka University
2015-2024
Graduate School USA
2014-2020
Olympus (Japan)
2013-2018
Kyoto Institute of Technology
2016
Japan Science and Technology Agency
2008-2012
Kyoto University
2003-2010
A new miniature multiturn time-of-flight (TOF) analyzer “MULTUM-S II” has been designed and constructed. This instrument consists of an electron ionization source, the TOF ion optics, a detector, vacuum system, electronic circuits. The four electrostatic toroidal sectors two additional electric for purpose injection/ejection. size weight system is less than 50 cm × 57 30 35 kg (including pumps circuits). capable high mass resolution because its infinite flight path utilizing perfect space...
Periodontitis is one of the most prevalent threats to oral health as common cause tooth loss. In order perform effective treatment, a clinical test that detect sites where disease activity high and predicts periodontal tissue destruction strongly desired, however, it still difficult prognose breakdown on basis conventional methods. The aim this study examine usefulness gas chromatography/mass spectrometry (GC/MS), which could eventually be used for on-site analysis metabolites in gingival...
A 16Mpixel 3D stacked CMOS image sensor with pixel level interconnections using 4,008,960 micro bumps at a 7.6μm pitch, which set no layout restriction and causes harm to characteristics, was developed achieve both global-shutter mode −180dB PLS 2Mpixel 10000fps high speed capturing mode.
Systematic examinations are carried out experimentally about the contribution of background vorticity distributions (BGVD's) to spontaneous formation and decay ordered arrays (vortex crystals) composed strong vortices (clumps) by using a pure-electron plasma. It is found that BGVD level needs be higher for an increasing number clumps form vortex crystals constituting crystal decreases in time as proportional gamma lnt contrast t (-xi) with xi approximately 1 accepted well turbulence models....
Conventional CMOS image sensors widely used in products currently on the market are mainly equipped with a rolling exposure function. This causes so-called "Jell-o effect" distortion when capturing moving target. global-shutter function one of solutions to avoid this distortion. An in-pixel storage node is required create sensor. A floating diffusion and an additional capacitor can be as [1,2]. The light sensitivity specified by parasitic (PLS), which ratio photodiode. PLS should small...
We have developed a 3-D-stacked 16-Mpixel, 3.8- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> pitch, and global shutter (GS) CMOS image sensor with 2-Mpixel 10 000-frames/s high-speed image-capturing mode, four million reliable microbump interconnections. This consists of photodiode (PD) substrate an in-pixel storage node substrate. The PDs in the unit pixel...
We have developed a new ion extraction method for stigmatic matrix-assisted laser desorption/ionization (MALDI) imaging time-of-flight (TOF) mass spectrometer.The conventional delayed is unsuitable TOF spectrometer because the ions disperse until and distribution not preserved imaging.In proposed method, temporal spatial focusing can be simultaneously achieved, enabling high-fidelity image to obtained with high resolution.This expected applicable cellular-level observations by spectrometry.
This paper presents the initial results of confinement weakly magnetized pure lithium ion (Li+) plasmas. Time evolutions two-dimensional images are successfully investigated for first time, using an end-on fluorescent screen attached to a micro-channel plate. Simultaneously, total particle numbers Li+ plasmas obtained from secondary electron current. Despite formed plasma being “kinetic” and density on order Brillouin limit, image is not disrupted. The occurs over period ≈9 s, which likely...
The solar power sail can generate sufficient electric to drive the high specific ion engine in outer planetary region by thin-film cells attached entire surface of spin-type sail. This paper proposes direct exploration using sail-craft. target is an unexplored D/P-type Jovian Trojan asteroid. A lander separated from sail-craft collect and underground samples asteroid perform in-situ analysis. delivers for sample return Earth as optional goal. Scientific observations during interplanetary...
A novel stigmatic mass microscope using laser desorption/ionization and a multi-turn time-of-flight spectrometer, MULTUM-IMG, has been developed. Stigmatic ion images of crystal violet masked by fine square mesh grid with 12.7 μm pitch as well microdot patterns 5 dot diameter 10 made rhodamine B were clearly observed. The estimated spatial resolution was about 3 in the linear mode 20-fold optical magnification. Separating according to time-of-flight, i.e., mass-to-charge ratio ions...
Elementary processes in free-decaying two-dimensional (2D) turbulence are examined by extensive analyses of fine structures the density distribution a magnetized pure electron plasma that is linearly unstable with initial ring-shaped profile, deforms nonlinearly into patches vortices, and relaxes single-peaked stable via successive mergers among patches. The stochastic dynamics decreasing number vortices real space correspond to time evolution energy spectra E(k) wave (k) transfers down...
Observations have shown that two discrete vortices (clumps) immersed in a broad profile of background vorticity merge quickly or form binary state lasts for long period. The different paths the vortical evolution critically depend on slight differences initial distribution (BGVD). By fine control BGVD asymptotic inter-clump distance is found to be two-valued function ∇ζb/ζb2, where ζb BGV at location clumps, corresponding merger and state. multiplicity removed by considering degree depletion...
Measurement methods of spatial distribution molecules such as proteins and drugs at cellular-scale are required in many fields including pathology, pharmacology, etc. Recently, sanning type imaging mass spectrometry (IMS) with matrix-assisted laser desorption/ionization (MALDI) is intensively used for biomolecular analysis. However, the resolution MALDI-IMS limited by focus diameter to about 10–100 µm inadequate observation. Therefore, we developing a stigmatic MALDI spectrometer, which...
A simple, effective accurate mass assignment procedure for a time-of-flight spectrometer is desirable. External calibration using standard together with an internal reference (lock mass) common technique assignment, however, polynomial fitting can result in mass-dependent errors. By the multi-turn infiTOF-UHV, we were able to obtain multiple data from ion monitored under several different numbers of laps that was then used calculate equation. We have developed acquisition system...
We demonstrated multiband imaging with a multi-storied photodiode CMOS image sensor (CIS), which comprises two individually functioning layered devices that achieve optimized images in different substrates bonded by 3D technology. The is able to capture wide variety of images, not limited conventional visible RGB (Red Green Blue) taken Bayer filter or invisible infrared (IR) at the same time without any color degradation even an extra IR light source. Its range sensitivity enables us select...
Intermittent leakages of trapped ions from a Penning trap are clearly explained. Two mechanisms revealed by considering both experimental and numerical results. The initial leakage is due to energized the potential barrier that just closing form positive well. following induced an axial average oscillation bulk ions. Some individual bounce pushed out barriers owing space bulk.
A fast scheme is proposed for determining the three-dimensional density distribution of a pure electron plasma under thermal relaxation in Penning trap on basis observation axially integrated distribution. The analysis that includes contribution conducting wall reveals appearance halo surrounding core around midplane. confirmed to approach Penning-type equilibrium Also new temperature determination electrons by analyzing radial profile particles extracted with energy selection. This method...
A simple-structured imaging system is constructed for observing two-dimensional electron density distributions over a wide dynamic range and with high spatial resolution. It consists of phosphor plate, an image-transfer lens charge-coupled-device (CCD) camera. The reliable operation the CCD camera experiments in strong magnetic field (<2.2 T) requires positioning at large distance from plasma trap. We successfully introduce three-lens transferring images to low distortion optical efficiency....
The accumulation of radioactive substances in biological organisms is a matter great concern since the incident at nuclear power plant Fukushima, Japan. We have developed novel technique for observing distribution accumulated metal cations fish that employs new imaging mass spectrometer, MULTUM-IMG2. Distributions 133Cs and 88Sr sliced section medaka (Oryzias latipes) are obtained with spatial resolution µm-scale.