A5101642613- Renal and related cancers
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Cancer Research and Treatments
- FOXO transcription factor regulation
- Protease and Inhibitor Mechanisms
- Kruppel-like factors research
- E-Government and Public Services
- Human Mobility and Location-Based Analysis
- Urban Transport and Accessibility
- Caveolin-1 and cellular processes
- Epigenetics and DNA Methylation
- Rock Mechanics and Modeling
- Thyroid Cancer Diagnosis and Treatment
- Rough Sets and Fuzzy Logic
- High-pressure geophysics and materials
- Virus-based gene therapy research
- Cancer, Hypoxia, and Metabolism
- Microtubule and mitosis dynamics
- Cancer Cells and Metastasis
- Transportation Planning and Optimization
- Biochemical and Molecular Research
- Video Analysis and Summarization
- Data Mining Algorithms and Applications
Southwest Medical University
2024
Jiangsu Province Special Equipment Safety Supervision and Inspection Institute
2023
Nankai University
2023
Guangdong University of Technology
2022
Xi'an University of Technology
2018-2021
Chinese People's Liberation Army
2013-2019
Stanford University
2019
People's Liberation Army No. 150 Hospital
2017
Wuhan University
2014
Chinese General Hospital College of Nursing and Liberal Arts
2014
To explore the mechanisms underlying clear-cell renal cell carcinoma (ccRCC) metastasis using transcriptional profiling and bioinformatics analysis of ccRCC samples, to elucidate role FOXO3a in metastasis.Gene expression was performed four primary metastatic five nonmetastatic samples. The mRNA protein levels samples were investigated by real-time reverse transcription PCR immunohistochemistry, respectively. association between metastasis-free survival patients with analyzed. Biologic...
Despite the successful progress next-generation sequencing technologies has achieved in diagnosing genetic cause of rare Mendelian diseases, current diagnostic rate is still far from satisfactory because heterogeneity, imprecision, and noise disease phenotype descriptions insufficient utilization expert knowledge clinical genetics. To overcome these difficulties, we present a novel method called Xrare for prioritization causative gene variants diagnosis.We propose new similarity scoring...
The far upstream element (FUSE)-binding protein 1 (FUBP1) is a transactivator of human c-myc proto-oncogene transcription, with important roles in carcinogenesis. However, the expression pattern and potential biological function FUBP1 clear cell renal carcinoma (ccRCC) yet to be established.FUBP1 was detected ccRCC tissues lines by real-time RT-PCR, Western blot analysis, immunohistochemistry. correlations mRNA levels clinicopathological factors were evaluated. during tumor proliferation...
// Xiang-Jun Lyu 1, * , Hong-Zhao Li Xin Ma 1 Xin-Tao Yu Gao Dong Ni 2 Dong-Lai Shen Liang-You Gu Bao-Jun Wang Zhang Xu Department of Urology/State Key Laboratory Kidney Diseases, Chinese People's Liberation Army General Hospital/PLA Medical School, Beijing, Republic China Urology, Zhongnan Hospital, Wuhan University, Wuhan, These authors have contributed equally to this work Correspondence to: Zhang, e-mail: dr.xuzhang@hotmail.com Keywords: clear cell renal carcinoma, tumorigenesis, S100A6,...
To systematically validate and calibrate the theory technology of deep in-situ condition-preserved coring, conditions at different depths should be simulated, full-size coring tests carried out in this simulated environment. Therefore, a deep-rock calibration platform was designed developed. The self-tightening sealing structure quick-disassembly were on basis an innovative segmented nonuniform-diameter structure, which breakthrough from traditional high-pressure vessel frame verified by...
Coupon personalized placement recommendations are presented in this paper, which use XGBoost algorithm to predict whether coupons used by users for a certain period of time. In grid search method was adjust the parameters, and model continuously optimized. The final AUC value 0.8496, suggestions were made coupons, thereby increasing merchant sales profits. Experimental results demonstrate that based on can better contribute precision marketing.
The unreasonable setting of urban bus stops is a common problem in real life, which seriously affects people’s happiness, sense belonging and brand the city. However, existing related research on above problems generally has defects high technical complexity cost. Therefore, we aim to propose way optimize public transportation stations reduce cost station optimization by using artificial intelligence algorithms. First, extract integrate GPS data card swipe business system perform exploratory...
Objective To study the effect of Ras homolog gene family members B （RhoB） on pro- liferation and apoptosis renal cell carcinoma line 786-0. Methods The eukaryotic expression vector pcDNA3. 0-Flag-RhoB was constructed transfected into 786-0 cells using liposome-mediate method. RhoB protein level in detected by Western blotting. effects prolifera- tion ceils were analyzed MTS method flow cytometry. Results O-Flag-RhoB successfully constructed. blotting indica- ted that highly expressed cells....