A5101996589- Microscopic Colitis
- Gut microbiota and health
- Inflammatory Bowel Disease
- Advanced Neural Network Applications
- Clostridium difficile and Clostridium perfringens research
- Statistical Methods and Inference
- Gastrointestinal motility and disorders
- Genetic factors in colorectal cancer
- Automated Road and Building Extraction
- Parallel Computing and Optimization Techniques
- Child Nutrition and Feeding Issues
- Robotics and Sensor-Based Localization
- Helicobacter pylori-related gastroenterology studies
- Visual Attention and Saliency Detection
- Machine Learning and ELM
- Eosinophilic Esophagitis
- Epigenetics and DNA Methylation
- Advanced Image Fusion Techniques
- Colorectal Cancer Screening and Detection
- Infant Health and Development
- Prenatal Screening and Diagnostics
- CCD and CMOS Imaging Sensors
- Robotic Path Planning Algorithms
- Gene expression and cancer classification
Beijing Institute of Technology
2023
Stony Brook University
2014-2019
Applied Mathematics (United States)
2018
Pediatrics and Genetics
2018
Stony Brook University Hospital
2018
Washington University in St. Louis
2018
Cincinnati Children's Hospital Medical Center
2018
In order to assess potential associations between autism spectrum disorder (ASD) phenotype, functional GI disorders and fecal microbiota, we recruited simplex families, which had only a single ASD proband neurotypical (NT) siblings, through the Simons Simplex Community at Interactive Autism Network (SSC@IAN). Fecal samples metadata related diet were collected from probands NT siblings of (age 7-14). Functional gastrointestinal (FGID) assessed using parent-completed ROME III questionnaire for...
Mutation of the adenomatous polyposis coli (APC gene), an early event in adenoma-carcinoma sequence, is present 70-80% sporadic human colorectal adenomas and carcinomas. To test hypothesis that mutation APC gene alters microbial interactions with host intestinal mucosa prior to development polyposis, culture-independent methods (targeted qPCR assays Illumina sequencing 16S rRNA V1V2 hypervariable region) were used compare composition 30 six-week old C57BL/6 APCMin/+ congenic wild type (WT)...
Background Incidence and mortality rates of colorectal carcinoma (CRC) are higher in African Americans (AAs) than Caucasian (CAs). Deficient micronutrient intake due to dietary restrictions racial/ethnic populations can alter genetic molecular profiles leading dysregulated methylation patterns the inheritance somatic germline mutations. Materials Methods Total DNA RNA samples paired tumor adjacent normal colon tissues were prepared from AA CA CRC specimens. Reduced Representation Bisulfite...
Transformer, which originates from machine translation, is particularly powerful at modeling long-range dependencies. Currently, the transformer making revolutionary progress in various vision tasks, leading to significant performance improvements compared with convolutional neural network (CNN) based frameworks. In this paper, we conduct extensive research on exploiting contributions of transformers for accurate and reliable salient object detection. For former, apply a deterministic model,...
We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome ("dysbiosis") a patient cohort. Here we report an integrative analysis of expanded number Crohn's disease (CD) related genetic defects innate immune function (NOD2, ATG16L1, IRGM, CARD9, XBP1, ORMDL3) composition by combining initial cohort (Batch 1, 2005–2010, n = 165) second consecutive 2, 2010–2012, 118). These combined cohorts were composed three...
To examine the relationship between elevated granulocyte-macrophage colony-stimulating factor (GM-CSF) auto-antibodies (Ab) level and time to surgical recurrence after initial surgery for Crohn's disease (CD).We reviewed 412 charts from a clinical database at tertiary academic hospital. Patients included in study had ileal or ileocolonic CD resection of small bowel ileocecal region management disease. Serum samples were analyzed serological assays including GM-CSF cytokine, Ab, ASCA IgG IgA,...
Classic multinomial logit model, commonly used in multiclass regression problem, is restricted to few predictors and does not take into account the relationship among variables. It has limited use for genomic data, where number of features far exceeds sample size. Genomic such as gene expressions are usually related by an underlying biological network. Efficient network information important improve classification performance well interpretability. We proposed a model that capable addressing...
To further improve the capacity of airborne embedded system for dealing with deep learning (DL) applications and reduce overall power consumption, it is necessary to equip Neural Processing Units (NPUs). Comparing cloud system, usually has a fixed application set, but strict real-time constraints. Unfortunately, inherent NPU scheduler does not consider priority, which cannot provide sufficient capability system. At present, there are few researches on multi-task scheduling NPUs. Therefore,...
Large-scale emergency rescue tasks require search and units to conduct autonomous exploration be able respond quickly in complex dangerous environments. This paper proposes a ground-aerial collaborative framework for scenarios. The heterogeneous system is composed of single unmanned aerial vehicle(UAV) ground vehicle(UGV). UAV responsible providing global topological map the airspace perspective performing path planning, UGV local obstacle avoidance. Collaborative has improved capabilities...
Introduction: Fecal microbiota transplant (FMT) has proven to be an effective method for treating Clostridium difficile infections and is currently under investigation Ulcerative Colitis (UC). Few studies have performed FMT both C. UC one protocol. We conducted uncontrolled prospective study characterize the of patients before after colonoscopic FMT. Methods: Patients with antibiotic refractory (n=15, 5 whom also had UC, 1 Crohn's Disease) only (n=5) were enrolled in study. Pre-transplant...