Background Red cell distribution width (RDW) is a hematological parameter routinely obtained as part of the complete blood count. Recently, RDW has emerged potential independent predictor clinical outcomes in adults with sepsis. However, mortality pediatric populations not been well established.Objective To determine relationship between value and sepsis patients.Methods We performed cross-sectional study 40 consecutive patients admitted to PICU from December 2013 March 2014. All patients’...

BACKGROUND: Beta thalassemia major is associated with lipid profile abnormalities, presented as a lower level of total cholesterol (TC), low-density lipoproteins (LDL), high-density lipoprotein (HDL), and higher triglyceride level; increasing risk for cardiovascular complications. The previous studies indicated that Vitamin D give positive impact on the in healthy children population. However, its role needs to be determined high-risk group beta-thalassemia major.
 AIM: To determine...

BACKGROUND: Sepsis in children is a significant cause of morbidity and mortality the pediatric intensive care unit (PICU). Assessment sepsis using serial Pediatric Logistic Organ Dysfunction (PELOD)-2 score can be used as prognostic factor. The use biomarkers also for diagnosis predicting outcomes. Many studies have suggested that C-reactive protein (CRP) procalcitonin (PCT) to predict mortality.METHODS: A prospective cohort study was conducted evaluate CRP, PCT, PELOD-2 its combination...

Sepsis in children with cardiovascular involvement can increase mortality. Recently, many studies have been conducted to investigate troponin as an early marker of myocardial dysfunction, associated pediatric sepsis score. Pediatric Logistic Organ Dysfunction 2 (PELOD-2) score is recent scoring assess organ dysfunction children.To determine the correlation between T, I PELOD-2 a predictive factor mortality.A prospective cohort study was on PICU Haji Adam Malik General Hospital, Medan....

Latar belakang. Pneumonia merupakan penyebab kematian 808.694 anak dibawah 5 tahun pada 2017 di dunia. Rerata jumlah harian balita akibat pneumonia 2007 adalah 83 anak. Peningkatan kadar prokalsitonin (PCT) secara signifikan berhubungan dengan peningkatan mortalitas, begitu pula rasio neutrofil limfosit (NLR) yang parameter sederhana untuk menilai status inflamasi subjek dan dapat memperkirakan mortalitas 30 hari pasien Community Acquired (CAP) khususnya pediatri.Tujuan. Studi ini bertujuan...

Immense efforts have been implemented by the North Sumatera government since beginning of Covid-19 pandemic to mitigate spread and increasing numbers cases. However, continued grow, Indonesia contributed one highest among children globally. Although cases in are commonly mild, but long-term health impact is still unknown. Therefore, protection against infection on first place highly important. We aimed determine prevalence high school students their knowledge, attitude practices (KAP)...

Background: Throughout the coronavirus disease (COVID-19) pandemic, it is critically important to determine prevalence of SARS-CoV-2 infection among community evaluate success control policy. Despite continually updated COVID-19 worldwide and in Indonesia, testing mainly focused only on symptomatic individuals.Objective: We aimed children adults asymptomatic population Medan, North Sumatera Province, Indonesia.Methods: conducted a cross-sectional study assess different districts Medan City,...

Pediatric patients with multiple organ failures in the pediatric intensive care unit (PICU) are at a higher risk of mortality. Assessing mortality when admitted to PICU is important allocate treatment and properly. The aim this study was compare performance PRISM IV score within first 24 72 hours predict PICU. Demographic, clinical, laboratory data were collected compute among critically ill H. Adam Malik General Hospital, Medan, Indonesia, from April 2021 February 2022. comparison scores...

BACKGROUND: Early detection and treatment of sepsis can prevent septic shock reduce mortality rate. Troponin become a prognostic factor in sepsis. However, not all health facilities are equipped to assess troponin levels. Vasoactive-inotropic score (VIS) is simpler more accessible method describe hemodynamic status. The aim this study was the suitability VIS as early prognosis predictor sepsisMETHODS: A retrospective conducted determine correlation between levels for cases Pediatric...

Menarche is a result of the complex interaction between hypothalamus, pituitary gland, and ovaries. Its timing influenced by combination genetic predisposition environmental factors, along with their interactions. Bisphenol A (BPA), chemical compound known as an endocrine disruptor due to its estrogenic properties can impact onset menarche. Therefore, research needs be carried out evaluate BPA exposure menarche in female adolescents. Methods: descriptive study adolescents aged 9-14 years old...

The molecular reverse transcription-polymerase chain reaction (RT-PCR) testing of respiratory tract swabs has become mandatory to confirm the diagnosis coronavirus disease 2019 (COVID-19). However, RT-PCR tests are expensive, require standardized equipment, and relatively long times, sample pooling method been introduced solve this issue. aim study was compare cycle threshold (Ct) values individual pooled methods assess how accurate was. Repeat examinations were initially performed Ct for...

Bisphenol A (BPA) is an endocrine-disrupting chemical widely used in various consumer products. Due to its estrogenic properties, BPA exposure suspected influence reproductive development, particularly the timing of menarche adolescent girls. The aim this study was assess relationship between urinary levels and age at among girls Sumatera Utara Province, Indonesia. cross-sectional conducted January 2023 involving 30 aged 9–14 years attending junior high school Utara. Data on age, body...

Background Trichuris trichiura is one of the most common soil-transmitted helminth that infects school-aged children. A single dose albendazole has been shown to have wide variations in cure and egg reduction rates. Some studies suggested repeated doses might increase its effectiveness.Objective To compare anti-trichuriasis effect 400 mg taken daily for five consecutive days vs. seven days.Methods randomized open clinical trial was conducted from August September 2009 on elementary school...

HIGHLIGHTS Leiomyoma is still the most common case in women aged 41–50 years. Women who have an obese BMI are main risk factor for abnormal uterine bleeding, so it urged to maintain ideal weight because can be bad health. ABSTRACT Objective: This study identified incidence of Abnormal Uterine Bleeding (AUB) at Haji Adam Malik General Hospital, Medan, Indonesia, 2020-2021. Materials and Methods: was a descriptive with cross-sectional design. Sampling taken using total sampling retrospective...

Objective. This study aims to assess the correlation of ferritin serum level and PELOD-2 score, determine effectiveness as early indicator organ dysfunction. Methods. was a cross-sectional carried out pediatric patients with sepsis in Pediatric Intensive Care Unit Haji Adam Malik Universitas Sumatera Utara hospital from June 2021 – January 2022. Complete blood work done, score were measured on first third day stay all sixty participants aged 1-18 years old sepsis. The using Spearman test,...

Sepsis is a life-threatening organ dysfunction caused by dysregulation of the immune response to infection. Antithrombin III single plasma bound glycoprotein and include class serine protease (serpine) inhibitors; its synthesis in liver decreases during sepsis.

Introduction: Fibrinogen is a prognostic biomarker in septic children, lower fibrinogen levels are closely related to higher risk of death. Organ dysfunction was diagnosed based on PELOD-2 score. The aim this study determine the corelation between and score as predictor mortality pediatric patient with sepsis treated PICU HCU at H. Adam Malik General Hospital. Method: A cross-sectional patients Hospital, Medan. Correlation scores seen day I III treatment aged 1 month 18 years hospital stay...

Background: PICU main focuses were on the area of life support with intensive monitoring and special care aiming save lives critically ill children, paying attention to physical psychological sequelae, trying maximize quality life. Researches survivors is still limited, especially in Indonesia. Objective: To assess relationship between age children care. Methods: A cross-sectional study patients aged 2-18 years a history being treated at Haji Adam Malik Hospital, Medan, from January 2017-...

Background: Helicobacter pylori (H. pylori) is one of the causes intestinal and gastric ulcers or factors causing malignancy. The prevalence H. infection more than 80% in developing countries. Probiotics provide beneficial effects on host?s health when administered an adequate amount. Lactobacillus Bifidobacteria are most commonly used as probiotics. H.pylori colonization interfered with by regular ingestion L. acidophilus, urea breath test values decreased approximately 10% four weeks after...

This study aimed to find the accuracy of HPSA test with CLO in diagnosing helicobacter pylori gastritis children. The cross sectional conducted on 57 children October 2019 up May 2020. Subject were between two until eighteen years old who met inclusion and exclusion criteria. examination was performed patient's stool sample using rapid immunochromatographic monoclonal antibody for qualitative detection H. bacteria human feces. From samples, there 37 positively infected pillory. There no...

Abstract Background The immune system in human develops when they are exposed to severe helminth infections. Chronic soil-transmitted (STH) infection can modulate and suppress allergic reactions particularly by changing the responses from effector. This study observed how STH infections correlated with as determined skin prick test (SPT). Methodology Fourty-five primary school children recurrent (determined at least two positive results 4-monthly Kato Katz examination over a year period) who...

Introduction : Atherosclerosis is asymptomatic and its complications are chronic, slowly progressive cumulative. Serum ferritin tends to increase in ?-thalassemia major cases; hence, it can become an indicator for premature atherosclerosis. . The risk of atherosclerosis high cases. Objectives To identify the relationship between serum children with major. This research also provided prevalence correlation level lipid profile Material Methods was analytical cross-sectional study pediatric...

Background: Helicobacter pylori infection is the cause of most gastritis in world population. In establish and determining severity gastiritis, a combination clinical symptoms, physical examination, support laboratories needed. Gastritis chronic inflammation which can increase inflammatory markers, including CRP. Investigation such as CRP, measure level objectively, help to evaluate patient. Previous studies have shown that H.pylori causes increased CRP concentrations. Methods: This study...