We have developed an efficient protocol for the synthesis of spiro[indoline-pyridine]dicarboxylates and substituted alkylidene oxindoles through [3 + 3] cycloaddition Michael addition individually by azomethine ylides various MBH carbonates isatins. The selective generation cyclic products chain was achieved changing substituents at 3-position oxindoles. features this method include convenient catalysts, mild reaction conditions, broad substrate scopes.

We have developed an efficient protocol for the construction of polycyclic dihydrobenzofuran spirooxindole scaffolds via base promoted cascade annulation Morita-Baylis-Hillman (MBH) carbonates isatins with ortho-hydroxychalcones or ortho-hydroxy-β-nitrostyrenes. The complex compounds were conveniently synthesized in satisfactory yields and high diastereoselectivity. This provides a swift convenient approach assembly diverse highly functionalized spirooxindoles also features broad substrate...

A simple InBr3-catalyzed domino reaction of indoles, phenylacetylenes, and various 3-methyleneoxindolines in toluene is described. This not only provided a convenient synthetic protocol for polysubstituted tetrahydrospiro[carbazole-1,3′-indolines] good yields but also gave completely different diastereoisomers the to that previously reported TfOH-catalyzed one-pot acetophenones, 3-methyleneoxindolines. Additionally, initially prepared 1,1′-bis(indolyl)phenylethanes with...

A new DBU-catalyzed formal [4 ​+ ​2] cycloaddition between ortho-hydroxyphenyl-substituted para-quinone methides and electron-deficient dienophiles including 3-methyleneoxindoles 2-aryldeneindene-1,3-diones was established. wide range of functionalized spiro[chromane-3,3′-indolines] spiro[chromane-3,2′-indenes] were successfully synthesized in good yields with high diastereoselectivity. The features the reaction included readily available substrates, mild conditions, convenient methodology...

We have developed a convenient synthetic protocol for efficient construction of significant dihydrobenzofuran and benzofuran scaffolds by Lewis base-mediated annulation reaction ortho-iminophenols ortho-vinylphenols with MBH carbonates isatins under mild metal-free conditions. The selective generation different kinds derivatives was successfully achieved employing substituted isatin-derived ortho-N-tosyliminophenols ortho-vinylphenols. features included broad substrate scopes, excellent...

The presence of slit nanopores in MXene materials inevitably influences the electrochemical performance supercapacitor electrodes. However, most studies focus on experimental approaches, lacking microscopic-scale analysis. Here, we performed molecular dynamics (MD) simulations to thoroughly analyze and predict ion transport pathways energy storage mechanisms MXene/ionic liquid (IL) supercapacitors with ultradeep nanopores. simulation results indicate that during charging process, counterions...

Single transition metal atom embedding and functional group defect engineering is commonly utilized to optimize the electronic band structure of g-C3N4. However, most dual modification method suffers from destruction active sites. Herein, single Cu carboxyl dual-endowed g-C3N4 nanosheets with a tunable bandgap were prepared by employing facile CO2 plasma method. Experiments density theory calculation show that leads decreased reconstructed local charge distribution promote separation...

The thromboxane (Tx) A2 pathway is a major contributor to the amplification of initial platelet activation and therefore key drug target. To identify potent small-molecule inhibitors prostaglandin (TP) receptor, we screened small steroidal saponin library using U46619-induced rat aggregation assays. Timosaponin AIII (TAIII) was identified as inhibitor exhibited superior selectivity for TP receptor versus other G protein-coupled receptors PKC activator. TAIII inhibited independent increases...

For industrial flotation foam image processing, accurate bubble size measurement and feature extraction are very important to optimize the process improve recovery of mineral resources. This paper presents an improved algorithm investigate segmentation for processing. Several libraries implemented Python programming language used enhancement compensation, quantitative analysis factors influencing accuracy, suggestions improvement The characteristics-size morphology-and influence conditions...

Plasmonic and photonic nanostructures can manipulate light-matter interaction, leading to a wide range of tunable properties. Here, we show that multiple Fano plasmon resonances be generated in quasi-3D plasmonic nanostructure arrays on rectangle grid substrates. The are the quasiguided modes coupled with resonance while distinct localized surface top gold thin film sub-wavelength nanohole array bottom nanodisk array. tuned separately selectively by changing dimension nanostructures.

A new high-throughput surface plasmon resonance (SPR) biosensor based on differential interferometric imaging is reported. The two SPR interferograms of the sensing are imaged CCD cameras. phase difference between 180°. refractive index related factor (RIRF) calculated from simultaneously acquired interferograms. simulation results indicate that RIRF exhibits a linear relationship with and unaffected by noise, drift intensity distribution light source. affinity kinetic information can be...

A photo-cross-linkable carboxybetaine (CB)-terminated thiol with only one CB headgroup was introduced to modify gold nanoparticles (GNPs) via self-assembled monolayers (SAMs). This CB-terminated consists of three moieties: (a) an anchoring group, which binds directly the GNP surface, (b) a terminal is highly resistant protein adsorption, and (c) diacetylene group in middle, converted poly(enyne) structure during UV irradiation 1,4-topochemical polymerization. Results show that, after...

Stomatopods are creatures that have a unique ability to manipulate their environment by detecting polarized light for finding prey, choosing habitat, and navigation. In this study, based on the concept of polarization distance proposed Martin Jet al2014 [Proc. R. Soc. B281, 20131632], we analyzed several multi-channel models. The simulation experimental results revealed compared other models, four-channel model can significantly enhance contrast between target background, it exhibits...

Smoke generated during surgery affects tissue visibility and degrades image quality, affecting surgical decisions limiting further processing analysis. Polarization is a fundamental property of light polarization-resolved imaging has been studied applied to general restoration scenarios such as for smog or mist removal in underwater environments. However, there no related research application smoke removal. Due differences between haze scenarios, we propose an alternative degradation model...

Abstract NH 4 I promoted three‐component reaction of indoles, cyclic ketones and maleimides in toluene at 140 °C afforded polysubstituted fused pyrrolo[3,4‐ a ]carbazoles good yields. The mechanism included sequential Lewis acid catalyzed 3‐alkenylation indole, Diels‐Alder aromatization process. More importantly, the similar indoles acetophenones with two molecules refluxing resulted complex tetrahydro‐4,10 ‐[3,4]epipyrrolopyrrolo[3,4‐ satisfactory yields via double reaction. On other hand,...

Researchers have found that some animals can use the skylight polarization pattern for navigation. It is also expected to human navigating in near future. However, challenge need a more accurate and efficient model of imaging always felt. In this paper, three improved models are proposed. The proposed utilize analysis distribution after system. Given system distorted, focus paper on degree distortion these models. Experiments clear weather conditions demonstrate operates close actual...

Chrysocolla is a kind of copper oxide mineral which was difficult to float.In this study, Diethyldithiocarbamate (DDTC) employed modify the surface chrysocolla improve its xanthate adsorption and floatability.Flotation experiments showed that DDTC exhibited ability activate rather than acting as collector for flotation.After activation, can be effectively recovered by xanthate.The activation mechanism investigated via Fourier transform infrared (FT-IR) spectroscopy X-ray photoelectron...