A5063769582- Children's Physical and Motor Development
- Obesity, Physical Activity, Diet
- Head and Neck Surgical Oncology
- Hearing Loss and Rehabilitation
- Ear Surgery and Otitis Media
- Physical Activity and Health
- Head and Neck Cancer Studies
- Obstructive Sleep Apnea Research
- Dysphagia Assessment and Management
- Virus-based gene therapy research
- Meningioma and schwannoma management
- CAR-T cell therapy research
- Congenital Ear and Nasal Anomalies
- Vestibular and auditory disorders
- Advanced MRI Techniques and Applications
- Tracheal and airway disorders
- Radiation Dose and Imaging
- Ear and Head Tumors
- Vascular Malformations Diagnosis and Treatment
- Infant Development and Preterm Care
- Mesenchymal stem cell research
- Blood transfusion and management
- Atrial Fibrillation Management and Outcomes
- Tumors and Oncological Cases
- Ferroptosis and cancer prognosis
Innsbruck Medical University
2013-2023
Universität Innsbruck
2015-2023
Medical University of Vienna
2014-2016
LMU Klinikum
2008
University Hospital Ulm
2004
With the increase in long-term survivorship of head and neck cancer (HNC), functional outcomes are gaining importance. We reported HNC patients using HNC-Functional InTegrity (FIT) Scales, which is a validated tool for rapid clinical assessment status based on observable criteria. Patients with newly diagnosed treated at Medical University Innsbruck between 2008 2020 were consecutively included, their six domains food-intake, breathing, speech, pain, mood, shoulder mobility was scored by...
Unfavorable clinical outcomes mean that cancer researchers must attempt to develop novel therapeutic strategies overcome resistance in patients with HNSCC. Recently, ferroptosis was shown be a promising pathway possessing druggable targets, such as xCT (SLC7A11). Unfortunately, little is known about the molecular mechanisms underlying susceptibility of HNSCC cells ferroptosis. The goal this study determine whether activated Erk1/2 are vulnerable induction. Our results have (SLC7A11)...
Physical activity (PA) and sedentary behaviors have been associated with various health outcomes in youth, including overweight/obesity physical fitness. Limited information, however, is available on the independent association between TV time fitness children adolescents.A total of 3,293 (55.1% male) youth 6 14 years age were randomly selected from 29 Austrian schools. Body weight height measured according to standard procedures BMI percentiles determined based German reference values. was...
The prevalence of overweight and obesity is increasing worldwide. impact on post-tonsillectomy haemorrhage rates in children adults unclear.Body mass index were evaluated all patients treated with tonsillectomy within one year a tertiary referral centre. Bleeding episodes categorised according to the Austrian Tonsil Study.Between June 2011 2012, 300 underwent tonsillectomy. Post-tonsillectomy occurred 55 patients. Of those, 29 type A (history blood saliva only, no active bleeding), 15 B...
Head and neck cancer etiology architecture is quite diverse complex, impeding the prediction whether a patient could respond to particular immunotherapy or combination treatment. A concomitantly arising caveat obviously translation from pre-clinical, cell based in vitro systems as well syngeneic murine tumor models towards heterogeneous of human ecosystems. To bridge this gap, we have established employed patient-derived HNSCC (head squamous carcinoma) slice culturing system assess...
Reduction of the radiation exposure involved in image-guided craniofacial and skull base surgery is an important goal. The purpose was to evaluate influence low-dose protocols modern multi-slice spiral computed tomography (MSCT) on target registration errors (TREs).An anthropomorphic phantom with markers at bone anterior scanned Sensation Open (40-slice), LightSpeed VCT (64-slice) Definition Flash (128-slice). Identical baseline (BP) 120 kV/100 mAs were compared following (LD) care dose/dose...
In 2005 the World Health Organization estimated that approximately 278 million people suffered from ‘moderate to profound hearing impairment,’ 80% of whom lived in low- and middle-income countries ...
Three-dimensional primary slice cultures (SC) of head and neck squamous cell carcinomas (HNC) are realistic preclinical models. Until now, preserving structure viability ex vivo for several days has been difficult. The aim this study was to optimize cultivation conditions HNC SC analyze the added effects platelet rich fibrin (PRF) on these conditions.SC were prepared from tumor biopsies 9 patients. Cultures incubated 1 7 in three different media- Keratinocyte serum-free medium (SFM),...
In a previous study, severe and cerebral malaria have been connected with acute cochlear malfunction in children, demonstrated by decrease of transitory evoked otoacoustic emissions (TEOAEs) reproducibility. This study aims to determine whether persists for 4 years after recovery from subset the study's collective. Follow-up TEOAEs were performed on site (CERMEL, Hôpital Albert Schweitzer, Lambaréné, Gabon) or at participants' homes; 33 out 90 participants included initial investigation...
Objective To reevaluate the frequency of perioperative blood transfusion, transfusion triggers, and survival impact in patients with incident, surgically treated head neck cancer (HNC) restrictive regimens. Methods Retrospective analysis incident HNC without between 2008 2019 at Department Otorhinolaryngology, Head Neck Surgery, Medical University Innsbruck, according to department's clinical Tumor Registry. Results Of 590 included, transfusions were administered 6.3% ( n = 37, group)....
<b>Hintergrund:</b> Im Rahmen eines Pilotprojektes wurde der Zusammenhang von Ernährungsverhalten und motorischer Leistungsfähigkeit an einer Neuen Mittelschule in Tirol 10- bis 14-jährigen Jugendlichen (n = 62) untersucht. <b>Methoden:</b> Die Beurteilung motorischen erfolgte anhand des Deutschen Motorik-Tests (DMT 6-18). Der Lebensmittelverzehr mittels Food Frequency Questionaires erfasst. sportliche Aktivität pro Tag Stunden ebenfalls Außerdem wurden BMI, Geschlecht Lebensalter...
<b>Hintergrund:</b> Karate erfreut sich sowohl im Profi- als auch Breitensport großer Beliebtheit. Die Einteilung der verschiedenen Stilrichtungen erfolgt anhand des Impacts in Voll-, Halb- und Lowkontakt. Ziel dieser Arbeit war die Analyse von Sportverletzungen Kyokushinkai- (Vollkontakt) traditionellem (Semikontakt). <b>Methoden:</b> Im Rahmen einer Querschnittsbefragung wurden insgesamt 215 aktive Amateurkarateka (114 Vollkontakt- 101 Semikontaktkarateka) mittels eines standardisierten...
The inverse association between body weight and physical fitness has been well documented but there remains limited information on the of change with development fitness, particularly in elementary school children. present study, therefore, examined status from ages 6 to 10 years 301 Austrian children (55.1% male). Body height were measured according standard procedures was assessed via German motor test (DMT 6-18) at baseline 4-year follow-up. Overweight/obesity determined using 90th BMI...
Zusammenfassung Im vorliegenden Artikel wird untersucht, inwiefern der Migrationshintergrund ein unabhängiger Faktor für die körperliche Fitness von Kindern und Jugendlichen ist oder ob sich beobachtete Unterschied durch andere Faktoren erklären lässt. An Erhebung nahmen 3293 Primarstufen- (7,7 ± 1,2 Jahre) Sekundarstufenschüler (11,5 teil. Das Untersuchungskollektiv erreichte mit einem Gesamtscore 103,5 6,9 eine überdurchschnittliche Leistung. Der Einfluss des Migrationshintergrunds konnte...
Cochlear implantation is a standard treatment option due to expanding indications. Cranial magnetic resonance imaging (cMRI) has become widespread diagnostic tool. Therefore, an increased number of cochlear implant (CI) users are undergoing cMRI scans. This study aimed investigate the issue CI magnet impacting MRI quality and artifacts. 1.5 T 3 scans with 4 defined sequences (T2-TSE, T2-TIRM, T1-3D-MPRAGE, TDI) were performed on phantom (SYNCHRONY System by MED-EL Austria) in place. The...
Objective: To evaluate 2D and 3D image quality of ultralow dose computed tomography images for navigated skull base surgery using adaptive statistical iterative reconstruction (ASIR) model-based (MBIR) compared with standard filtered back projection (FBP). Study Design: Cadaver study. Material Methods: A human cadaver head was scanned a high resolution reference protocol (CTDIvol 30.48 mGy) series five protocols (3.48, 2.19, 0.82, 0.44, 0.22 mGy). Subjective blinded axial FBP ASIR-50,...
Wir berichten von einem 58-jährigen, männlichen Patienten, der sich in unserer Ambulanz mit Rhinorrhoe, Epiphora und Hypästhesie rechten Wange seit 3 Monaten vorstellte. 5 Jahre zuvor war bei dem Mann ein Nierenzellkarzinom diagnostiziert partieller Nephrektomie therapiert worden. Seither bestand eine Vollremission.