- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Advancements in Transdermal Drug Delivery
- Adipokines, Inflammation, and Metabolic Diseases
- Exercise and Physiological Responses
- Phytochemicals and Antioxidant Activities
- Diet, Metabolism, and Disease
- Tea Polyphenols and Effects
- Muscle metabolism and nutrition
- Advanced Drug Delivery Systems
- Diabetes Treatment and Management
- Natural Antidiabetic Agents Studies
- Microencapsulation and Drying Processes
- Toxin Mechanisms and Immunotoxins
- Metabolism, Diabetes, and Cancer
- Cardiovascular Disease and Adiposity
- Alcohol Consumption and Health Effects
- Antioxidant Activity and Oxidative Stress
- Sirtuins and Resveratrol in Medicine
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Vitamin K Research Studies
- Lipid Membrane Structure and Behavior
- Autoimmune and Inflammatory Disorders Research
- Hormonal Regulation and Hypertension
Auburn University
2023-2025
Texas Tech University
2018-2023
Arizona State University
2021-2023
University College London Hospitals NHS Foundation Trust
2023
University College London
2023
Shahid Beheshti University of Medical Sciences
2015-2019
National Nutrition and Food Technology Research Institute
2015-2019
University of Tennessee at Knoxville
2019
Jean Mayer Human Nutrition Research Center on Aging
2019
Tufts University
2019
Mirabegron, a <i>β</i>3-adrenergic receptor agonist, has been shown to stimulate the activity of brown fat and increase resting metabolic rate in humans. However, it is unknown whether mirabegron can reduce body weight improve health. We investigated antiobesity effects using both vitro vivo models. Mouse preadipocytes 3T3-L1 cells were treated with different concentrations (0.03–3 <i>µ</i>g/ml), expression fat-related genes was measured by quantitative real-time polymerase chain reaction....
Obesity is a serious public health problem that strongly associated with increased multiple comorbidities such as diabetes, cardiovascular disease, and some types of cancer. While current anti-obesity treatments have various issues, locally transforming energy-storing white adipose tissue (WAT) into energy-burning brown-like/beige tissue, the so-called browning WAT, has been suggested to enhance obesity treatment efficiency minimized side effects. Metformin first-line antidiabetes drug...
Background/Objectives: The relationship between diet, micronutrient supplementation, and metabolic regulation emphasizes the potential of nutritional strategies to address obesity related disorders. Certain vitamins have enhance thermogenesis health. However, impact multivitamin supplementation on white adipose tissue (WAT) browning, gut microbiome (GM), function is not well understood. This study investigated effects obesity-related dysfunction in mice fed a high-fat diet (HFD) or low-fat...
Non-alcoholic fatty liver disease (NAFLD) is the most common which has become a public health concern. Since oxidative stress plays crucial role in pathogenesis of NAFLD, subsequent hematological disorders are expected. Therefore, antioxidant compounds such as quercetin could ameliorate related side-effect stress. The aim current study was to assess effect on parameters NAFLD patients. A randomized, double-blind, placebo-controlled trial conducted pilot study. In this 90 patients with were...
Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety this population has never been investigated. This study was to evaluate the of a 12-week supplementation annato tocotrienol postmenopausal women, along with effects on quality life, body composition, physical activity, and nutrient intake population. Eighty nine women were randomly assigned 3 treatment arms: (1) Placebo (430 mg olive oil/day), (2) Low tocotrientol (Low TT) tocotrienol/day...
Several studies have shown significant associations between manganese superoxide dismutase (MnSOD) Val16Ala polymorphism and diabetic complications, but this association has not been explored in relation with chronic kidney disease (CKD) Type 2 diabetes mellitus (T2DM) patients. Total antioxidant capacity (TAC) level changes condition may play important role onset or progression of the its complications. The present study investigated MnSOD serum TAC risk CKD T2DM This nested case-control...
Purpose Non-alcoholic fatty liver disease (NAFLD) is the most common which has become a public health concern, whose growing prevalence been reported as around 33.9% in Iran. As oxidative stress plays crucial role pathogenesis of NAFLD, antioxidant compounds such quercetin could ameliorate side effect stress. The aim current study was to assess on lipid profile, enzymes and inflammatory indices NAFLD patients. Design/methodology/approach In randomized, double-blind, placebo-controlled trial...