Mehrnaz Abbasi

ORCID: 0000-0003-4287-2133
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About
Contact & Profiles
Research Areas
  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Advancements in Transdermal Drug Delivery
  • Adipokines, Inflammation, and Metabolic Diseases
  • Exercise and Physiological Responses
  • Phytochemicals and Antioxidant Activities
  • Diet, Metabolism, and Disease
  • Tea Polyphenols and Effects
  • Muscle metabolism and nutrition
  • Advanced Drug Delivery Systems
  • Diabetes Treatment and Management
  • Natural Antidiabetic Agents Studies
  • Microencapsulation and Drying Processes
  • Toxin Mechanisms and Immunotoxins
  • Metabolism, Diabetes, and Cancer
  • Cardiovascular Disease and Adiposity
  • Alcohol Consumption and Health Effects
  • Antioxidant Activity and Oxidative Stress
  • Sirtuins and Resveratrol in Medicine
  • Nutritional Studies and Diet
  • Liver Disease Diagnosis and Treatment
  • Vitamin K Research Studies
  • Lipid Membrane Structure and Behavior
  • Autoimmune and Inflammatory Disorders Research
  • Hormonal Regulation and Hypertension

Auburn University
2023-2025

Texas Tech University
2018-2023

Arizona State University
2021-2023

University College London Hospitals NHS Foundation Trust
2023

University College London
2023

Shahid Beheshti University of Medical Sciences
2015-2019

National Nutrition and Food Technology Research Institute
2015-2019

University of Tennessee at Knoxville
2019

Jean Mayer Human Nutrition Research Center on Aging
2019

Tufts University
2019

Mirabegron, a <i>β</i>3-adrenergic receptor agonist, has been shown to stimulate the activity of brown fat and increase resting metabolic rate in humans. However, it is unknown whether mirabegron can reduce body weight improve health. We investigated antiobesity effects using both vitro vivo models. Mouse preadipocytes 3T3-L1 cells were treated with different concentrations (0.03–3 <i>µ</i>g/ml), expression fat-related genes was measured by quantitative real-time polymerase chain reaction....

10.1124/jpet.118.255778 article EN Journal of Pharmacology and Experimental Therapeutics 2019-04-02

Obesity is a serious public health problem that strongly associated with increased multiple comorbidities such as diabetes, cardiovascular disease, and some types of cancer. While current anti-obesity treatments have various issues, locally transforming energy-storing white adipose tissue (WAT) into energy-burning brown-like/beige tissue, the so-called browning WAT, has been suggested to enhance obesity treatment efficiency minimized side effects. Metformin first-line antidiabetes drug...

10.3390/pharmaceutics14040879 article EN cc-by Pharmaceutics 2022-04-17

Background/Objectives: The relationship between diet, micronutrient supplementation, and metabolic regulation emphasizes the potential of nutritional strategies to address obesity related disorders. Certain vitamins have enhance thermogenesis health. However, impact multivitamin supplementation on white adipose tissue (WAT) browning, gut microbiome (GM), function is not well understood. This study investigated effects obesity-related dysfunction in mice fed a high-fat diet (HFD) or low-fat...

10.3390/nu17061045 article EN Nutrients 2025-03-17

Non-alcoholic fatty liver disease (NAFLD) is the most common which has become a public health concern. Since oxidative stress plays crucial role in pathogenesis of NAFLD, subsequent hematological disorders are expected. Therefore, antioxidant compounds such as quercetin could ameliorate related side-effect stress. The aim current study was to assess effect on parameters NAFLD patients. A randomized, double-blind, placebo-controlled trial conducted pilot study. In this 90 patients with were...

10.7762/cnr.2020.9.1.11 article EN Clinical Nutrition Research 2020-01-01

Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety this population has never been investigated. This study was to evaluate the of a 12-week supplementation annato tocotrienol postmenopausal women, along with effects on quality life, body composition, physical activity, and nutrient intake population. Eighty nine women were randomly assigned 3 treatment arms: (1) Placebo (430 mg olive oil/day), (2) Low tocotrientol (Low TT) tocotrienol/day...

10.1186/s12906-018-2263-0 article EN cc-by BMC Complementary and Alternative Medicine 2018-06-28

Several studies have shown significant associations between manganese superoxide dismutase (MnSOD) Val16Ala polymorphism and diabetic complications, but this association has not been explored in relation with chronic kidney disease (CKD) Type 2 diabetes mellitus (T2DM) patients. Total antioxidant capacity (TAC) level changes condition may play important role onset or progression of the its complications. The present study investigated MnSOD serum TAC risk CKD T2DM This nested case-control...

10.1186/s12986-018-0264-0 article EN cc-by Nutrition & Metabolism 2018-04-11

10.1016/j.jddst.2023.105110 article EN publisher-specific-oa Journal of Drug Delivery Science and Technology 2023-11-16

Purpose Non-alcoholic fatty liver disease (NAFLD) is the most common which has become a public health concern, whose growing prevalence been reported as around 33.9% in Iran. As oxidative stress plays crucial role pathogenesis of NAFLD, antioxidant compounds such quercetin could ameliorate side effect stress. The aim current study was to assess on lipid profile, enzymes and inflammatory indices NAFLD patients. Design/methodology/approach In randomized, double-blind, placebo-controlled trial...

10.1108/nfs-10-2019-0321 article EN Nutrition & Food Science 2020-04-10
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