A5022399570- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Rheumatoid Arthritis Research and Therapies
- Knee injuries and reconstruction techniques
- Advanced Radiotherapy Techniques
- Porphyrin and Phthalocyanine Chemistry
- Osteoarthritis Treatment and Mechanisms
- Bone fractures and treatments
- Lung Cancer Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Hip and Femur Fractures
- Mesenchymal stem cell research
- Glioma Diagnosis and Treatment
- Plant and animal studies
- Bone Metabolism and Diseases
- Cancer Diagnosis and Treatment
- Insect and Arachnid Ecology and Behavior
- Bone health and treatments
- Immune Response and Inflammation
- Management of metastatic bone disease
- Cytokine Signaling Pathways and Interactions
- Medical Imaging Techniques and Applications
- X-ray Diffraction in Crystallography
Kobe University
2016-2025
Fujita Health University Hospital
2023-2024
Kobe Institute Of Computing
2021-2024
Daido University
2024
Kobe University Hospital
2024
The University of Tokyo
1975-2024
Konica Minolta (Japan)
2024
Fukuoka University
2021-2023
Kyoto University
1966-2023
Canon (Japan)
2023
The micromechanics involved in increased crack growth resistance, K R , due to the addition of TiB 2 particulate a SiC matrix was analyzed both experimentally and theoretically. fractography evidence, which, advancing attracted adjacent particulates, attributed tensile region surrounding particulate. Countering this effect is compressive thermal residual stress, which results toughening composite, matrix. This stress field particulate‐reinforced ceramic‐matrix composite induced by mismatch...
SIRT1 is known to inhibit apoptosis and promote survival of various types cells. However, the roles in human chondrocytes have never been reported. We undertook this study investigate relationship chondrocytes, which a characteristic feature osteoarthritis (OA).The expression was examined by reverse transcription-polymerase chain reaction, immunoblotting, immunohistology cartilage samples. The under catabolic, mechanical, nutritional stresses investigated immunoblotting. To examine effect on...
We have searched the human genome for genes that predispose to rheumatoid arthritis (RA) using fluorescence-based microsatellite marker analysis and affected sib-pair linkage study. A panel of 41 Japanese families, each with at least two siblings, was typed genome-wide 358 polymorphic loci. Markers were amplified by PCR fluorescence-tagged primers sized based on difference CA repeats DNA. Linkage made maximum lod score (MLS). The MLS D1S214 D8S556 3.27 3.33, while HLA-DRB1 region <3.0....
A novel naphthyl-fused zinc porphyrin carboxylic acid has been synthesized and employed successfully in a dye-sensitized TiO2 solar cell, with power conversion efficiency of 4.1%, which is improved by 50% relative to the unfused reference cell.
5,10,15,20-Tetrakis(2,4,6-trimethylphenyl)-6'-carboxyquinoxalino[2,3-β]porphyrinatozinc (II) (ZnQMA) and 5,10,15,20-tetrakis(2,4,6-trimethylphenyl)-6',7'-dicarboxyquinoxalino[2,3-β]porphyrinatozinc (ZnQDA) have been synthesized to evaluate the effects of β,β'-carboxyquinoxalino moieties on structure optical, electrochemical, photovoltaic properties porphyrins. Both ZnQMA ZnQDA exhibited broadened red-shifted light absorption in UV−visible spectra compared with...
ADVERTISEMENT RETURN TO ISSUEPREVNoteChitosan NanofiberKousaku Ohkawa, Ken-Ichi Minato, Go Kumagai, Shinya Hayashi, and Hiroyuki YamamotoView Author Information Institute of High Polymer Research, Faculty Textile Science Technology, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Japan Cite this: Biomacromolecules 2006, 7, 11, 3291–3294Publication Date (Web):September 28, 2006Publication History Received6 May 2006Revised1 September 2006Published online28 inissue 1 November...
Novel unsymmetrically π-elongated porphyrins, in which the naphthyl moiety is fused to porphyrin core at bridge with a carboxyl group (fused-Zn-1) or opposite side of phenyl (fused-Zn-2), have been synthesized improve light-harvesting abilities porphyrin-sensitized solar cells. As results π-elongation low symmetry, Soret and Q bands fused-Zn-1 fused-Zn-2 were red-shifted broadened, intensity Q-band relative that band was enhanced. The fused-Zn-2-sensitized TiO2 cells showed power conversion...
A series of meso-tetraphenylzincporphyrins have been prepared to examine the effects porphyrin substituents and adsorption conditions on photovoltaic properties porphyrin-sensitized TiO2 cells. The cell performance strongly depended linking bridge between core surface, bulkiness around core, immersing solvents times for adsorption. In particular, high cells was achieved when protic solvent (i.e., methanol) short time (0.5−1 h) were used dye TiO2, which is in sharp contrast with Ru...
The aim of this study was to compare the post-operative radiographic and clinical outcomes between kinematically mechanically aligned total knee arthroplasties (TKAs).A 60 TKAs (30 30 aligned) were performed in patients with varus osteoarthritis using a navigation system. angles orientation joint line relation floor, conventional true mechanical axis (tMA) (the from centre hip lowest point calcaneus) compared, one year post-operatively, on single-leg double-leg standing long leg radiographs...
Introduction Surgical site infection is one of the most severe complications surgical treatments. However, optimal procedure to prevent such infections remains uninvestigated. Ultraviolet radiation C (UVC) with a short wavelength has high bactericidal effect; however, it cytotoxic. Nonetheless, given that UVC 222 nm reaches only stratum corneum, does not affect skin cells. This study aimed investigate safety 222-nm irradiation and examine its sterilization effect in healthy volunteers....
Novel 5-(5-carboxy-2-thienyl)-10,15,20-tris(2,4,6-trimethylphenyl)-porphyrinatozinc(II) (Zn5S), 5-(5-carboxy-2-furyl)-10,15,20-tris(2,4,6-trimethylphenyl)porphyrinatozinc(II) (Zn5O), and 5-(4-carboxy-2-thienyl)-10,15,20-tris(2,4,6-trimethylphenyl)porphyrinatozinc(II) (Zn4S) were synthesized to evaluate the spacer effects on structures of porphyrin films photovoltaic properties porphyrin-sensitized TiO2 solar cells. Each porphyrins showed different adsorption behavior saturated coverage...
A new synthetic method of spirooxindole derivatives has been developed by way a palladium-catalyzed decarboxylative cyclization gamma-methylidene-delta-valerolactones with isatins. By employing newly prepared phosphoramidite ligand, the reaction proceeds smoothly excellent diastereoselectivity. Preliminary results its application to asymmetric catalysis using chiral ligand are also described.
Electrode structures and photovoltaic properties of porphyrin-sensitized solar cells with TiO2 Nb-, Ge-, Zr-added composite electrodes were examined to disclose the effects partial substitution Ti atom by other metals in electrodes. The prepared sol-gel process using laurylamine hydrochloride as a template for formation micellar precursors yielding well-defined mesoporous nanocrystalline structures, cases silica titania tubules nanoparticles templating mechanism. characterized transmission...
Background: Portal vein embolization (PVE) is now widely accepted as a useful preoperative procedure in selected patients undergoing extended hepatectomy. However, the effect of PVE on growth liver tumors has not been fully elucidated. Purpose: To retrospectively evaluate effects embolized lobes. Material and Methods: Eight with primary tumor, six hepatocellular carcinomas (HCC) two cholangiocellular (CCC), were studied. The rates lobes non-embolized parenchyma calculated using computed...
Subporphyrin borenium cations with a carborane counterion have been prepared by treatment of B-methoxy subporphyrins the silylium reagent Et(3)Si(CH(6)B(11)Br(6)). In contrast to distinctly domed subphthalocyanine cation, nearly planar structure sp(2) hybridized boron is found in X-ray triphenylsubporphyrin cation. The exhibit absorption and fluorescence spectra that are quite similar those subporphyrins. B-phenyl were good yield reaction subporphyrin phenyllithium.
Nintedanib, a tyrosine kinase inhibitor that is specific for platelet-derived growth factor receptors (PDGFR), fibroblast (FGFR), and vascular endothelial (VEGFR), has recently been approved idiopathic pulmonary fibrosis. Fibrocytes are bone marrow-derived progenitor cells produce factors contribute to fibrogenesis in the lungs. However, effects of nintedanib on functions fibrocytes remain unclear. Human monocytes were isolated from peripheral blood healthy volunteers. The expression their...
A series of palladium complexes bearing a bisphosphine monoxide with methylene linker, that is, [κ2-P,O-(R12P)CH2P(O)R22]PdMe(2,6-lutidine)][BArF4] (Pd/BPMO), were synthesized and evaluated as catalysts for the homopolymerization ethylene copolymerization polar monomers. X-ray crystallographic analyses revealed these Pd/BPMO exhibit significantly narrower bite angles longer Pd-O bonds than phenylene while maintaining almost constant Pd-P bond lengths. Among synthesized, menthyl-substituted...
Clostridium perfringens beta toxin is known to be the primary pathogenic factor of necrotic enteritis in type C strains that produce toxin. The was purified from supernatant fluid a culture controlled at pH 7.5 using an anti-alpha affinity column (1Sakurai J. Duncan C.L. Infect. Immun. 1977; 8: 741-745Crossref Google Scholar) or Toyopearl HW 60 (2Sakurai Fujii Y. Toxicon. 1987; 25: 1301-1310Crossref PubMed Scopus (37) Scholar). Beta possesses lethal, dermonecrotic, and pressor activities...
A new method was developed for the assay of ornithine decarboxylase (ODC)-antizyme complex, in which alpha-difluoromethylornithine (DFMO)-inactivated ODC used to release active competitively from complex. ODC-antizyme complex present extracts hepatoma tissue-culture (HTC) cells and ODC-stabilized variant HMOA cells, much larger amounts latter. Cellular fluctuated after a change medium similar manner HTC increasing during period decay. After treatment with cycloheximide, decay more rapid than...
Abstract Objective Chondrocyte apoptosis plays an important role in cartilage degeneration osteoarthritis (OA), and mechanical injury to induces chondrocyte apoptosis. In response DNA damage, p53 expression is up‐regulated, transcription activity increased, signals are initiated. The p53‐regulated apoptosis‐inducing protein 1 (p53AIP‐1) one of the genes, activated damage. This study was undertaken analyze function after induction by shear strain chondrocytes. Methods OA samples were obtained...
We describe the preparation of cellulose nanofibrous material directly from solution via electrospinning. The resulting nanofiber is composed pure cellulose. spinning procedure can be performed under ambient conditions at room temperature without post-spun treatment. By mixing drugs with pre-spun solution, followed by electrospinning, drug-loaded was prepared and releasing properties were examined respect to biomedical applications.
ABSTRACT Eicosapentaenoic acid (EPA) is an antioxidant and n‐3 polyunsaturated fatty that reduces the production of inflammatory cytokines. We evaluated role EPA in chondrocyte apoptosis degeneration. Normal human chondrocytes were treated with sodium nitroprusside (SNP). Expression metalloproteinases (MMPs) was detected by real‐time polymerase chain reaction (PCR) apoptosis‐related proteins western blotting. Chondrocyte flow cytometry. C57BL/6J mice used for detection MMP expression...