A5074206104- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Mechanical Circulatory Support Devices
- Anesthesia and Neurotoxicity Research
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Respiratory Support and Mechanisms
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Aortic aneurysm repair treatments
- Electrolyte and hormonal disorders
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac tumors and thrombi
- Heart Failure Treatment and Management
- Tracheal and airway disorders
- Acute Ischemic Stroke Management
- Cardiac electrophysiology and arrhythmias
Nippon Medical School
2006-2020
Nippon Medical School Musashi Kosugi Hospital
2017-2019
Chiba Hokusou Hospital
2007
NIHR Bristol Cardiovascular Biomedical Research Unit
2002-2004
Hy-Line (United States)
2004
RELX Group (Netherlands)
2004
University of Bristol
2001-2003
Bristol Royal Infirmary
2001-2002
Bristol Royal Hospital for Children
2002
Royal Hospital for Sick Children
2001
Background —Current cardioplegic protection techniques used in pediatric cardiac surgery do not take into consideration age and cyanotic differences. The aim of the present work was to address this question by monitoring clinical outcome, myocardial metabolism, reperfusion injury patients protected cold-crystalloid cardioplegia. Methods Results —Fifty-eight (31 children 27 infants) with or without hypoxic stress (cyanosis) undergoing open heart cardioplegia were included study. Clinical...
Abstract Backgound: Perioperative myocardial injury is determined by the ischemic duration, pathology, and preoperative status. Our aim was to evaluate pathology-related differences in troponin I (TnI) release, a sensitive specific marker of injury, its relation clinical outcome after pediatric open heart surgery. Methods: Troponin measured serially postoperatively 133 children undergoing repair atrial (ASD, n = 41) ventricular septal defects (VSD, 46), tetralogy Fallot (TOF, 46). The length...
The general anesthetic propofol protects the adult heart against ischemia and reperfusion injury; however, its efficacy has not been investigated in immature heart. This work, for first time, investigates cardioprotective of at clinically relevant concentrations Langendorff perfused rabbit hearts (7–12 days old) were exposed to 30 minutes’ global normothermic followed by 40 reperfusion. Left ventricular developed pressure (LVDP) coronary flow monitored throughout. Lactate release into...
AF in Mitral Valve Disease. Introduction : Patients with mitral valve disease frequently have atrial fibrillation (AF), and the left atrium is presumed to be primary that develops AF. However, it still not clear whether electrophysiologic abnormalities responsible for are confined this subset of patients. Methods Results To examine vulnerability each atrium, we measured wavelength homogeneity conduction at lateral right Bachmann's bundle after defibrillation seven patients undergoing maze...
Volume-rendering computed tomography (CT) without contrast medium has clearly demonstrated the 3-D mapping of saphenous vein (SV). Contrastless volume-rendering CT was used to preoperatively evaluate SV anatomy before coronary artery bypass grafting (CABG). This technique useful for atypical anatomical variations, such as partial duplication (Case 1) or varicose veins 2). may also help with redo CABG (to determine remaining SV) during endoscopic harvesting restricted view. is an objective,...
Hypoalbuminemia is an independent prognostic factor in hospitalization for heart failure (HHF). or proteinuria related to resistance loop diuretics. Tolvaptan oral non-peptide, competitive antagonist of vasopressin receptor-2. It has been used the treatment volume overload HHF patients several Asian countries. Several studies have demonstrated marked improvement congestion patients. However, whether tolvaptan useful with hypoalbuminemia (both which are diuretics) not clarified. We examined...
Objective: To determine pulmonary functional changes that predict early clinical outcomes in valve surgery requiring long cardiopulmonary bypass (CPB). Methods: This retrospective study included 225 consecutive non-emergency surgeries with fast-track cardiac anesthesia between January 2014 and March 2020. Blood gas analyses before 0, 2, 4, 8, 14 h after CPB were investigated. Results: Median age EuroSCORE II 71.0 years (25–75 percentile: 59.5–77.0) 2.46 (1.44–5.01). Patients underwent 96...
Background: Cerebrovascular disease (CVD) with brain hypoperfusion is a strong risk factor for stroke. However, how this pathology influences long-term outcomes after coronary artery bypass graft (CABG) surgery not known. Methods: Magnetic resonance imaging/angiography (MRI/A) of the neck and was performed in 318 out 575 consecutive CABG patients between May 2005 April 2018. Critical CVD chronic defined as multiple severe stenoses (⩾70%) and/or occlusion carotid vertebral systems associated...
Haemolytic anaemia due to a stenosed graft is rare complication after surgery for aortic dissection. We present the case of patient with haemolytic and heart failure, who had undergone emergent ascending aorta replacement type A acute dissection 5 years earlier. Chest computed tomography revealed severe stenosis proximal anastomosis transthoracic echocardiography showed regurgitation. Surgical treatment was necessary because failure myocardial ischaemia During operation, we found an inner...
BackgroundEarly extubation (EEx) after cardiac surgery has been essentially studied in patients with short cardiopulmonary bypass (CPB). Whether preoperative spirometry can predict EEx remains controversial.ObjectivesTo investigate whether be a goal and predicted by valve requiring long CPB.MethodsNonemergent consecutive 210 who underwent from January 2014 to August 2019 were investigated retrospectively.ResultsEEx (<8 h) was achieved 93 (44.3%) without increasing adverse events. Patients...
Narrowed true lumen and patent false through to the terminal aorta is a high-risk condition for malperfusion syndromes (MS) in acute type-A aortic dissection. It important ascertain how lumens behave after surgery.We retrospectively investigated 45 patients with this pathology. The sizes at narrowest levels above below superior mesenteric artery were followed by computed tomography surgery (0-36 months).Thirty-seven MS seen 23 patients. Hospital mortality was 8.9%. narrowed not enlarged...