A5021388898- Soil erosion and sediment transport
- Landslides and related hazards
- Hydrology and Sediment Transport Processes
- Hydrology and Watershed Management Studies
- Contact Dermatitis and Allergies
- Flood Risk Assessment and Management
- Synthetic Aperture Radar (SAR) Applications and Techniques
- Precipitation Measurement and Analysis
- Antenna Design and Optimization
- Antenna Design and Analysis
- Soil Moisture and Remote Sensing
- Cryospheric studies and observations
- Advanced SAR Imaging Techniques
- Dam Engineering and Safety
- Hydraulic flow and structures
- Occupational exposure and asthma
- Meteorological Phenomena and Simulations
- Antimicrobial agents and applications
- Geotechnical Engineering and Analysis
- Climate change and permafrost
- Geophysics and Gravity Measurements
- Animal testing and alternatives
- Soil and Unsaturated Flow
- Earthquake and Disaster Impact Studies
- Earthquake and Tsunami Effects
Kyoto University
2014-2025
Prevention Institute
2008-2023
Fujifilm (Japan)
2013-2022
Japan Chemical Industry Association
2015
Kanazawa University
2009-2011
Tokyo University of Science
2008
Pharmac
2008
Nihon University
2002-2008
Tokyo Metropolitan Institute of Medical Science
2003-2005
Ministry of Internal Affairs and Communications
1994-2005
To develop a testing strategy incorporating the human cell line activation test (h-CLAT), direct peptide reactivity assay (DPRA) and DEREK, we created an expanded data set of 139 chemicals (102 sensitizers 37 non-sensitizers) by combining existing 101 through collaborative projects Japan Cosmetic Industry Association. Of additional 38 chemicals, 15 with relatively low water solubility (log Kow > 3.5) were selected to clarify limitation strategies regarding lipophilic chemicals....
The skin sensitization potential of chemicals has been determined with the use murine local lymph node assay (LLNA). However, in recent years public concern about animal welfare led to a requirement for non-animal risk assessment systems prediction potential, replace LLNA. Selection an appropriate vitro test or silico model descriptors is critical obtain good predictive performance. Here, we investigated utility artificial neural network (ANN) models using various combinations from several...
Abstract The direct peptide reactivity assay (DPRA) is a simple and versatile alternative method for the evaluation of skin sensitization that involves reaction test chemicals with two peptides. However, this requires concentrated solutions chemicals, hydrophobic substances may not dissolve at concentrations required. Furthermore, precipitate when added to solution. We previously established high‐sensitivity method, amino acid derivative (ADRA). This uses novel cysteine (NAC) lysine...
ABSTRACT On August 9–10, 2021, the Koakagawa Bridge in Mutsu, Aomori Prefecture, Japan, collapsed owing to flood caused by a tropical cyclone. In this study, cause of collapse was examined. The characteristics inundation with bypassing flows and countermeasures for bank erosion due channel blockage driftwood were investigated based on field surveys numerical simulations. scouring bed around bridge pier found be leading failure. Channel would have damage left bank, top is bare sediment,...
Abstract In this paper, an approach for the use of spaceborne SAR data rice field identification, as well land classification, is demonstrated, by using multitemporal acquired over Ohgata-mura area, Akita, Japan with ERS-1 C-band SAR, in 1992. Two techniques reducing influence speckle on accuracy identification were tested. A comparison results survey collected 1993, and Landsat TM data, shows potential present approach.
Abstract The amino acid derivative reactivity assay (ADRA) is an in chemico alternative to animal testing for skin sensitization that solves certain problems found the use of direct peptide (DPRA). During a recent validation study conducted at multiple laboratories as part process include ADRA existing OECD test guideline, one nucleophilic reagents used ADRA— N ‐(2‐(1‐naphthyl)acetyl)‐ l ‐cysteine (NAC)—was be susceptible oxidation much same manner cysteine DPRA was. Owing this, we undertook...
Abstract The spatial distribution of hazard risk due to debris flows is discussed using a horizontal two-dimensional numerical simulation flow, and the hazards are evaluated according type damage. Compared areas between flow depth building destruction, many inundated by outside hazardous area for destruction. destruction sediment deposition, there almost no overlap two areas. In other words, away from stream exit does not suffer severe damage such as buildings, but it completely free...
The tissue distribution and disposition of carnitine, which plays an important role in the transport long-chain fatty acids across mitochondrial inner membrane for β-oxidation, are well controlled by carnitine transporter organic cation/carnitine 2 (OCTN2). Since little information is available on regulation expression OCTN2 gene, we examined factors that affect level rat Octn2 (rOctn2), focusing nuclear receptor peroxisome proliferator activated alpha (PPARα), regulates genes associated...
A two-dimensional debris and mud flow model that considers both laminar turbulence was developed. Subsequently, the applied to a occurred in Asaminami, Hiroshima, Japan August 2014. The applicability of characteristics are discussed. calculated horizontal distribution sediment deposited Asaminami residential area good agreement with large rocks driftwood. This result indicates fine material downstream transported by water resulting from heavy rain after flow. scale initial small; however, it...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationRelationship between Thermal Extraction Yield and Softening Temperature for CoalsTakahiro Yoshida, Toshimasa Takanohashi, Kinya Sakanishi, Ikuo Saito, Masaharu Fujita, Kiyoshi MashimoView Author Information Institute Energy Utilization, National of Advanced Industrial Science Technology, 16-1 Onogawa, Tsukuba, Ibaraki-ken, 305-8569, Japan College Nihon University, 1-8 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8308, Cite this: Fuels 2002, 16, 4,...
A polarimetric calibration experiment of Shuttle Imaging Radar C (SIR-C) is carried out using several different targets. These are C-band active radar calibrators (PARCs), polarization selective dihedrals (PSDs), 22.5/spl deg/ rotated dihedrals, and a trihedral. novel algorithm proposed that combines existing algorithms uses one PARC two PSDs. An error evaluation example shown to estimate the typical hardware value targets allowable for given error. The gives results comparable those...
This paper concerns an estimation algorithm of rain rates for a dual‐frequency radar at rain‐attenuating bands. The estimations are made based on the concept least squares. In algorithm, ratios received echo powers adjacent range bins each frequency used to eliminate some unknown and/or undetermined factors, such as calibration factors. which is applicable when part echoes one missing due attenuation, also developed. relationship between specific attenuation and rate ( k ‐ R relationship),...
Gamma-butyrobetaine (GBB) is a precursor in the biosynthesis of carnitine, which plays an important role beta-oxidation fatty acids, and converted to carnitine by gamma-butyrobetaine dioxygenase (BBD) predominantly liver. We investigated molecular mechanism hepatic uptake GBB rat hepatocytes. Cellular localization Octn2 (rOctn2:Slc22A5) was studied Western blot analysis. Uptake deuterated (d(3)-GBB) examined HEK293 cells expressing rOctn2 (HEK293/rOctn2) freshly isolated d(3)-GBB quantified...
The Communications Research Laboratory (CRL) of Ministry Posts and Telecommunications, in Japan is currently conducting a research on high-speed indoor wireless communication systems at the 60 GHz band. transmission rate targeted as high 156 Mbs. into key technology items also development model band are two major objectives project CRL. activity millimeter-wave LAN introduced. includes such multipath characteristics, antennas, anti-multipath techniques.