A5102743557- Diabetes Treatment and Management
- Cancer Immunotherapy and Biomarkers
- Antiplatelet Therapy and Cardiovascular Diseases
- Colorectal Cancer Treatments and Studies
- Peptidase Inhibition and Analysis
- Lung Cancer Treatments and Mutations
- PARP inhibition in cancer therapy
- Oral and gingival health research
- Pharmacovigilance and Adverse Drug Reactions
- Drug-Induced Adverse Reactions
- Connective tissue disorders research
- Pharmacology and Obesity Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Prostate Cancer Treatment and Research
- Antimicrobial Resistance in Staphylococcus
- Toxin Mechanisms and Immunotoxins
- Bone health and treatments
- Glioma Diagnosis and Treatment
- Food Allergy and Anaphylaxis Research
- Cancer Diagnosis and Treatment
- Pharmaceutical studies and practices
- Neuroendocrine Tumor Research Advances
- Bone and Joint Diseases
- CAR-T cell therapy research
- Neutropenia and Cancer Infections
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Peking Union Medical College Hospital
2025
Beijing Chao-Yang Hospital
2020-2023
Capital Medical University
2018-2023
Yang Hospital
2022
iQIYI (China)
2021
Peking University
2018-2020
Beijing Shijitan Hospital
2018-2020
Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used due to their profound efficacy in glycemic control and weight management. Real-world observations have revealed potential neuropsychiatric adverse events (AEs) associated with GLP-1RAs. This study aimed comprehensively investigate characterize these AEs Methods We analyzed GLP-1RA reaction reports using the FDA Adverse Event Reporting System database. Disproportionality analysis reporting odds ratio...
Introdution: Immune checkpoint inhibitors (ICIs) have significantly improved clinical outcomes for a wide range of cancers but can also lead to serious or fatal immune-related adverse events (irAEs). Although ICI-related pericardial toxicities been reported, the features are not well characterized in real-world studies. Objective: To characterize main and identify factors associated with death. Methods: Data from January 1, 2011 March 31, 2020 FDA Adverse Event Reporting System database were...
Introduction: Cutaneous adverse events are commonly reported immune-related (irAEs), some of which serious or even life-threatening, and it is essential to study these specific cutaneous AEs understand their characteristics risk. Methods: We performed a meta-analysis published clinical trials for immune checkpoint inhibitors (ICIs) evaluate the incidence events, using data from PubMed, Embase, Cochrane Library databases. Results: A total 232 with 45,472 patients were involved. Results showed...
Objectives Assessing the knowledge, attitude and practices (KAP) regarding health self-management among patients with osteogenesis imperfecta (OI) in China. Design An online cross-sectional survey. Setting A structured questionnaire was distributed through China-Dolls Center for Rare Disorders (CCRD), a non-governmental charity Participants were all OI from CCRD. After stratified sampling according to economic level of residential city, 901 proportionally selected 869 completed survey...
Immune checkpoint inhibitors (ICIs) are associated with different immune-related adverse events (irAEs), but there is limited evidence regarding the association between urinary incontinence and ICIs.We described case of a patient experiencing who later experienced series irAEs such as myocarditis, myositis, neurologic diseases while on ICI treatment in our hospital. In addition, we queried Food Drug Administration (FDA) Adverse Event Reporting System (FAERS) from third quarter 2010 to 2020...
Background: Immune checkpoint inhibitors (ICIs), including anti-PD-1/L1 therapy and anti-CTLA-4 therapy, are associated with a unique spectrum of immune-related adverse events (irAEs). The association clinical features ICIs-related biliary disorders not well characterized. Methods: Data were extracted from the US Food Drug Administration Adverse Event Reporting System (FAERS) database. Bile duct gallbladder diseases defined by Medical Dictionary for Regulatory Activities (MedDRA). We...