A5092272529- Pancreatic function and diabetes
- Autophagy in Disease and Therapy
- Wound Healing and Treatments
- Spinal Cord Injury Research
- RNA Interference and Gene Delivery
- Nerve injury and regeneration
- Genetics, Bioinformatics, and Biomedical Research
- Lipid metabolism and biosynthesis
- Endodontics and Root Canal Treatments
- Science, Research, and Medicine
- Adipose Tissue and Metabolism
- Computational Drug Discovery Methods
- Metabolomics and Mass Spectrometry Studies
- Anorectal Disease Treatments and Outcomes
- Cardiomyopathy and Myosin Studies
- Vagus Nerve Stimulation Research
- Biomedical Research and Pathophysiology
LipidALL Technologies (China)
2023-2025
Ningbo No. 2 Hospital
2025
Rice University
2024-2025
Precise remote control of skeletal muscle contraction could be beneficial to the study and treatment muscular dysfunction. Recently, we reported a method regulating intracellular calcium signaling using molecular motors (MMs), molecules that rotate sub-molecular components unidirectionally upon absorption light. Here, explore application this methodology tissue. Our results demonstrate MMs induce release in C2C12 myoblasts differentiated myotubes via IP3-mediated fashion depends on their...
ABSTRACT Lipotoxicity plays a crucial role in the progression of diabetic kidney disease (DKD), yet dynamic changes renal lipid composition from diabetes to early‐stage DKD remain unclear. Free fatty acids, lactosylceramides and cardiolipin (CL) were identified as most significantly altered lipids by quantitatively comparing targeted cortex classic spontaneous db/db mice using high‐coverage lipidomics. Further investigation into causes effects decreased CL, which is unique mitochondrial...
Dear Editor: We herein suggest that Fusobacterium nucleatum (F. nucleatum) disrupts anastomotic healing. It promotes the movement and activation of neutrophils, which increases MMPs production. These break down collagen, weakening anastomosis causing leakage. Anastomotic leakage (AL) is a critical potentially fatal complication may arise following colorectal surgery.1, 2 Despite its clinical significance, no specific risk factors or surgical techniques have been identified can effectively...
Objective: To investigate whether F.nucleatum affects the chemotherapy resistance of colorectal cancer by regulating ABC subfamily G subtype 2 (ABCG2), in view fact that correlation between two has not been reported. Methods: Oxaliplatin was used to interfere with cells and co-cultured establish a chemotherapy-induced model microbial infection. Calcein AM/PI cell staining, trypan blue counting kit 8 (CCK-8) method were detect activity. Real-time fluorescence quantitative polymerase chain...
One of the most challenging tasks in modern medicine is to find novel efficient cancer therapeutic methods with minimal side effects. The recent discovery several classes organic molecules known as "molecular jackhammers" a promising development this direction. It that these can directly target and eliminate cells no impact on healthy tissues. However, underlying microscopic picture remains poorly understood. We present study utilizes theoretical analysis together experimental measurements...