A5087662023- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic floor disorders treatments
- Stoma care and complications
- Anorectal Disease Treatments and Outcomes
- Hernia repair and management
- Appendicitis Diagnosis and Management
- Pelvic and Acetabular Injuries
- Enhanced Recovery After Surgery
- Intraperitoneal and Appendiceal Malignancies
- Abdominal Surgery and Complications
- COVID-19 and healthcare impacts
- Hip and Femur Fractures
- Diverticular Disease and Complications
- Intestinal and Peritoneal Adhesions
- Neuroendocrine Tumor Research Advances
- Minimally Invasive Surgical Techniques
- Gastric Cancer Management and Outcomes
- Inflammatory Bowel Disease
- Anesthesia and Pain Management
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Virus-based gene therapy research
- Ultrasound in Clinical Applications
University Hospital of Wales
2015-2025
Cardiff and Vale University Health Board
2020-2025
Cardiff University
2020-2024
University of Wales Institute Cardiff
2024
Hebron University
2024
St James's University Hospital
2022
Leeds Teaching Hospitals NHS Trust
2022
South Warwickshire NHS Foundation Trust
2022
Royal College of Surgeons of England
2021-2022
Royal Alexandra Hospital
2021
Acute appendicitis (AA) is the most common general surgical emergency. Early laparoscopic appendicectomy gold-standard management. SARS-CoV-2 (COVID-19) brought concerns of increased perioperative mortality and spread infection during aerosol generating procedures: as a consequence, conservative management was advised, open recommended when surgery unavoidable. This study describes impact first weeks pandemic on AA in United Kingdom (UK).
Introduction As a result of improving survival rates, the adverse consequences rectal cancer surgery are becoming increasingly recognised. Low anterior resection syndrome (LARS) is one such consequence and describes constellation bowel symptoms after which includes urgency, faecal incontinence, stool clustering incomplete evacuation. LARS has significant impact on quality life (QoL) present in up to 75% patients first year surgery. Despite this, little known about natural history there poor...
PURPOSE: This study was designed to investigate sexual and urinary dysfunction in women who underwent rectal cancer excision, the influence of tumor treatment variables on long-term outcomes. METHODS: Data were prospectively collected 295 excision at a tertiary referral colorectal center from 1998 2006. Sexual function assessed preoperatively intervals up five years after surgery. Functional outcomes by using univariate multivariate regression analysis, chi-squared test for trend, or...
The COVID-19 pandemic led to widespread disruption of colorectal cancer services during 2020. Established referral pathways were modified in response reduced diagnostic availability. aim this paper is assess the impact on referral, presentation and stage.This was a single centre, retrospective cohort study performed at tertiary centre. Patients diagnosed managed with adenocarcinoma between January December 2020 compared patients from 2018 2019 terms demographics, mode pathological staging.In...
Uncomplicated acute appendicitis can be managed with non-operative (antibiotic) treatment, but laparoscopic appendicectomy remains the first-line management in UK. During COVID-19 pandemic practice altered, more patients offered antibiotics as treatment. A large-scale observational study was designed comparing operative and of appendicitis. The aim this to evaluate 90-day follow-up.
Objectives: To develop and validate a predictive model to predict the risk of postoperative mortality after emergency laparotomy taking into account following variables: age, age ≥ 80, ASA status, clinical frailty score, sarcopenia, Hajibandeh Index (HI), bowel resection, intraperitoneal contamination. Summary Background Data: The discriminative powers currently available tools range between adequate strong; none has demonstrated excellent discrimination yet. Methods: TRIPOD STROCSS...
Attention is increasingly being turned to functional outcomes as central colorectal cancer (CRC) survivorship. The current literature may underestimate the impact of evacuatory dysfunction on patient satisfaction with bowel function after anterior resection (AR) for CRC. aim this study was investigate post-AR symptoms storage and health-related quality life (HRQoL).
Abstract Aim Incisional Hernia (IH) is a common complication of colorectal surgery, affecting up to 30% patients. There an association between surgeon experience and outcomes in hernia yet little regarding impact the performing abdominal wall closure (AWC) on IH rate. We aimed assess rates at 1 year following AWC junior senior surgeons patients undergoing surgery. Method This exploratory analysis who participated Hughes Abdominal Repair Trial (HART), prospective, multicentre randomised...
Incisional hernias cause morbidity and may require further surgery. HART (Hughes Abdominal Repair Trial) assessed the effect of an alternative suture method on incidence incisional hernia following colorectal cancer
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTBiosynthesis of Vitamin B6: The Oxidation 4-(Phosphohydroxy)-l-threonine by PdxADavid E. Cane, Yuju Hsiung, Julie A. Cornish, J. Kenneth Robinson, and Ian D. SpenserView Author Information Department Chemistry, Box H, Brown University Providence, Rhode Island, 02912 McMaster Hamilton, Ontario, L8S 4M1, Canada Cite this: Am. Chem. Soc. 1998, 120, 8, 1936–1937Publication Date (Web):March 4, 1998Publication History Received12 December...
Abstract Background Artificial bowel sphincter (ABS) and dynamic graciloplasty (DG) are surgical treatments for faecal incontinence (FI). FI may affect quality of life (QOL) so severely that patients often willing to consider a permanent end stoma (ES). It is unclear which the more cost‐effective strategy. Method Probability estimates with were obtained from published data (ABS, n = 319; DG, 301), supplemented by expert opinion. The primary outcome was quality‐adjusted years (QALYs) gained...