A5021129723- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Self-Assembly in Materials
- Lipid Membrane Structure and Behavior
- Marine Toxins and Detection Methods
- Chemical Reactions and Mechanisms
- Surfactants and Colloidal Systems
- Receptor Mechanisms and Signaling
- Photoreceptor and optogenetics research
- Supramolecular Chemistry and Complexes
- Radiopharmaceutical Chemistry and Applications
- Free Radicals and Antioxidants
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Nanocluster Synthesis and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Fluorescence Microscopy Techniques
- Polydiacetylene-based materials and applications
- Nanoplatforms for cancer theranostics
- Polymer Surface Interaction Studies
- Photochemistry and Electron Transfer Studies
- bioluminescence and chemiluminescence research
Centre National de la Recherche Scientifique
2012-2022
Université de Strasbourg
2012-2022
Laboratoire de Biophotonique et Pharmacologie
2012-2018
Pharmac
2014-2016
Taras Shevchenko National University of Kyiv
2015-2016
Dye-loaded lipid nano-droplets present an attractive alternative to inorganic nanoparticles, as they are composed of non-toxic biodegradable materials and easy prepare. However, achieve high fluorescence brightness, the have be heavily loaded with dyes avoiding self-quenching release (leakage) encapsulated from in biological media. In work, we designed highly lipophilic fluorescent derivatives 3-alkoxyflavone (F888) Nile Red (NR668) that can core stable nano-emulsion droplets at...
The key to ultrabright fluorescent nanomaterials is the control of dye emission in aggregated state. Here, lipophilic rhodamine B derivatives are assembled into nanoparticles (NPs) using tetraphenylborate counterions with varied fluorination levels that should tune short-range ordering. Counterion found drastically enhance characteristics these NPs. Highly fluorinated produce 10–20 nm NPs containing >300 dyes a fluorescence quantum yield 40–60% and remarkably narrow band (34 nm), whereas,...
The color, brightness and photostability of fluorescent polymer nanoparticles can be tuned by controlling aggregation encapsulated perylene diimide dyes.
Abstract The key challenge in the field of fluorescent nanoparticles (NPs) for biological applications is to achieve superior brightness sizes equivalent single proteins (3–7 nm). We propose a concept shell‐cross‐linked micelles, which PEGylated cyanine 3 and 5 bis‐azides form covalently attached corona on micelles amphiphilic calixarene bearing four alkyne groups. fluorescence quantum yield obtained monodisperse NPs, with size 7 nm, function viscosity reached up 15 % glycerol. In on‐state...
Herein, we show that a far-red arylidene-squaraine dye is stable against nucleophiles, in contrast to arene-squaraines. Owing the fluorescence enhancement apolar media together with high brightness and photostability, this was successfully applied detect oxytocin G protein-coupled receptor monitor its internalization living cells.
The ESIPT reaction speed of 4′-methoxy-3-hydroxyflavone varies by 3 orders magnitude depending on the H-bonding capabilities its environment.
A non-coordinating anion, fluorinated tetraphenylborate, assembles specially designed cationic cyanine amphiphiles into 7-8 nm fluorescent nanoparticles that are >40-fold brighter than a single dye. This kind of combining hydrophobic and electrostatic forces in aqueous media, constitutes promising building blocks the self-assembly functional nanomaterials.
The key challenge in the field of fluorescent nanoparticles (NPs) for biological applications is to achieve superior brightness sizes equivalent single proteins (3–7 nm). We propose a concept shell-cross-linked micelles, which PEGylated cyanine 3 and 5 bis-azides form covalently attached corona on micelles amphiphilic calixarene bearing four alkyne groups. fluorescence quantum yield obtained monodisperse NPs, with size 7 nm, function viscosity reached up 15 % glycerol. In on-state they are...
In this study, we explored how chemical reactions of amphiphile compounds can be characterized and followed-up on model interfaces. A custom-made surfactant containing three alkyne sites was first adsorbed at a water/oil interface. These amphiphiles then underwent interfacial crosslinking by click chemistry upon the addition second reactive agent. The monolayer properties dilatational elasticity, were compared before after polymerization. Using bulk phase exchange, composition aqueous finely...