A5059931908- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Helicobacter pylori-related gastroenterology studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Infections and bacterial resistance
- RNA modifications and cancer
- Bacterial Identification and Susceptibility Testing
- Plant Pathogens and Fungal Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Polar Research and Ecology
- Plant-Microbe Interactions and Immunity
- Innovative Microfluidic and Catalytic Techniques Innovation
- Supramolecular Self-Assembly in Materials
- Diabetes and associated disorders
- Obesity and Health Practices
- Virus-based gene therapy research
- Microbial bioremediation and biosurfactants
- Microbial Metabolism and Applications
- Nuclear Structure and Function
- Bone fractures and treatments
- RNA and protein synthesis mechanisms
- Latin American Legal and Economic Studies
- RNA regulation and disease
Universidad de La Frontera
2016-2024
Universidade de São Paulo
2008-2023
Clínica Alemana
2023
Weatherford College
2023
Production Development Corporation
1995
Enterobacteria-producing extended-spectrum β-lactamases (ESBL) play an important role in healthcare infections, increasing hospitalization time, morbidity and mortality rates. Among several ESBLs that emerge from these pathogens, CTX-M-type enzymes had the most successful global spread different epidemiological settings. Latin America presents high prevalence of CTX-M-2 ESBL-producing enterobacterial infections with local emergence CTX-M-1 group. However, this group has not yet been reported...
Helicobacter pylori colonizes half of the human population. Age, ethnicity, and socioeconomic status are factors that influence prevalence infection. This is important in southern Chile, one most unequal regions world, where a significant difference health access population occurs due to existence two competing systems. Moreover, last few years, current protocols H. eradication have shown high rates resistance with reduced therapeutic efficacy. study reported epidemiology infection attempted...
Background: Previous infection with Adenovirus-36 (HAdv-D36) has been associated adipogenesis and glycemic regulation in cell culture animal models. In humans, HAdv-D36 antibodies correlate increased obesity risk yet paradoxically enhance control across various demographics. This study assesses the association of seropositivity obesity, lipid, profiles among school-aged children. Methods: We evaluated 208 children aged 9–13, categorized by BMI z-scores into normal weight (−1 to +1),...
ABSTRACT We sequenced the oldest bla KPC-2 -bearing plasmid isolated in Brazil and another also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), 52 months later. Both plasmids present an IncN backbone few acquired regions. Because 2005 presented deletions truncated gene within Tn 4401b compared to 2009 plasmid, we can thus infer that pFCF1305 pFCF3SP had common ancestor circulating prior May 2005.
La alta capacidad de adaptación las bacterias a ambientes hostiles ha permitido el desarrollo resistencia antibacterianos, causando problemas impacto mundial en la salud hospitalaria y comunidad, limitando opciones terapéuticas lo que afecta control enfermedades, elevando tasas morbi-mortalidad. Esta es mediada por factores estructurales fisiológicos actúan diferentes niveles tanto extracelular como intracelular. A extracelulares se destaca poblaciones bacterianas formación biopelículas...
The extreme weather conditions in the Antarctic have exerted selective pressures favoring differential features bacteria to survive this untapped environment (i.e., antibiotic molecules). Notably, higher chances of discovery from extremophiles been proposed recently. Althoughnew organic and environmentally friendly sources for helping control plant pathogenic fungi are necessary, information about anti-phytopathogenic applications extremophile microorganisms environments is limited. In...
Summary Introduction Clopidogrel is commonly used in prevention and treatment of atherothrombosis. Some previous studies have suggested a pleiotropic effect clopidogrel; however, when this drug causes platelet‐independent effects on endothelial function remains unclear. Aims To evaluate the influence clopidogrel inflammatory biomarkers adhesion molecules human cells role nitric oxide ( NO ) process. Methods TNF ‐α‐induced umbilical vein HUVEC were exposed to clopidogrel. Gene expression...
Helicobacter pylori is the main bacteria associated with gastroduodenal diseases. Recent studies have reported that gastric microbiota might be modified by H. colonization, favoring lesions′ development. In Chile, region of La Araucanía concentrates a high risk cancer rurality, poverty, and Mapuche ethnicity. Hence, we aimed to identify culturable characterize its variability at different stages epithelial injury, based on colonization in dyspeptic patients from this Chilean region....
Experimental healing studies in humans are complex and difficult to replicate vitro. Hence, animal models needed study the different stages involved. The guinea pig (Cavia porcellus) is a model close human physiology, including lack of vitamin C synthesis, precursor collagen fibers for healing. thermal injury this makes it possible all healing, taking few days show tissue repair processes with without localized infection. aim work was systematize an experimental protocol on
RESUMEN:En los últimos años microorganismos tales como hongos, levaduras y, en especial, las bacterias han sido utilizadas para realizar biosíntesis de nanopartículas.Existen varios tipos descritas productoras nanopartículas, sin embargo, psicrófilas y psicrotolerantes no ampliamente estudiadas, aun cuando su utilización la producción nanopartículas podría entregar ventajas relacionadas con estabilidad, el gasto energético producción, al mismo tiempo que son una alternativa amigable medio...
Introduction: Linezolid has excellent activity against multidrug‐resistant Staphylococcus spp. and linezolid resistance emerged mainly in isolates recovered from patients who are receiving courses of oxazolidinone therapy. Case presentation: We report a clinical case bacteraemia caused by linezolid‐resistant epidermidis clone ST‐2 with the G2576T mutation five copies 23S rRNA gene (MIC, 32 µg ml−1) isolated patient did not receive any course The S. HSPE24‐SP strain was WT for L3, L4 L22...
(1) Background: Gastric cancer, the fourth most common cause of death from tumors in world, is closely associated with Helicobacter pylori. Timely diagnosis, therefore, essential to achieve a higher survival rate. In Chile, deaths gastric cancer are high, mainly due late diagnosis. Progranulin has reflected evolution some cancers, but been poorly studied lesions. Aiming understand role progranulin H. pylori infection and its development lesions, we evaluated genic expression tissue infected...
<title>Abstract</title> <bold>Background</bold> Adenovirus 36 (Ad-36) promotes adipogenesis and the development of human obesity. Induction PPARγ by Ad-36 seems to have a central role in maintenance adipogenic status. There is limited information about epigenetic mechanisms contributing this process adipose tissue. This study evaluated expression lncRNAs (<italic>ADINR, GAS5</italic> <italic>MEG3</italic>) miRNAs ((<italic>miR-18a</italic> <italic>miR-140</italic>) involved visceral tissue...