Kemeberly Charles

ORCID: 0000-0003-4398-7514
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About
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Research Areas
  • Frailty in Older Adults
  • Nutrition and Health in Aging
  • Palliative Care and End-of-Life Issues
  • Cancer survivorship and care
  • AI in Service Interactions
  • Health Systems, Economic Evaluations, Quality of Life
  • Mobile Health and mHealth Applications
  • Digital Platforms and Economics
  • Technology Adoption and User Behaviour
  • Technology Use by Older Adults
  • ICT Impact and Policies
  • Innovative Teaching and Learning Methods
  • Economic and Financial Impacts of Cancer
  • Digital Marketing and Social Media
  • Mobile Crowdsensing and Crowdsourcing
  • Breast Cancer Treatment Studies
  • Digital Mental Health Interventions
  • Context-Aware Activity Recognition Systems
  • Cancer Treatment and Pharmacology
  • Health and Wellbeing Research
  • Multiple and Secondary Primary Cancers
  • Team Dynamics and Performance
  • Health and Well-being Studies
  • Religion, Spirituality, and Psychology
  • Cancer-related cognitive impairment studies

City of Hope
2018-2024

Icahn School of Medicine at Mount Sinai
2024

City Of Hope National Medical Center
2024

University of California, San Diego
2021-2023

<h3>Importance</h3> Although geriatric assessment–driven intervention improves patient-centered outcomes, its influence on chemotherapy-related toxic effects remains unknown. <h3>Objective</h3> To assess whether specific (GAIN) can reduce in older adults with cancer. <h3>Design, Setting, and Participants</h3> A randomized clinical trial enrolled 613 participants from a National Cancer Institute–designated cancer center between 2015 2019. Patients were 65 years solid malignant neoplasm,...

10.1001/jamaoncol.2021.4158 article EN JAMA Oncology 2021-09-30

12010 Background: Geriatric assessment (GA) can predict chemotherapy (chemo) toxicity in older adults (age ≥65) with cancer. However, evidence regarding the effect of GA-driven intervention (GAIN) on incidence chemo has been limited. Therefore, we conducted a randomized controlled trial evaluating impact GAIN vs. standard care (SOC) Methods: Patients (pts) age ≥65, diagnosed solid malignancy, and starting new regimen at City Hope were eligible (NCT02517034). In 2:1 ratio, 600 pts randomly...

10.1200/jco.2020.38.15_suppl.12010 article EN Journal of Clinical Oncology 2020-05-20

10009 Background: Older adults with cancer facing decisions competing health outcomes may favor maintaining quality of life (QOL), independence, or cognition over prolonging survival. The goal this study was to elicit preferences among from older starting CT. Methods: This is a secondary analysis an ongoing prospective aimed at identifying and addressing vulnerabilities in (age ≥65) CT (NCT02517034). Patients completed 3 tools assessing outcomes: 1) Health Outcomes Tool: rates the relative...

10.1200/jco.2018.36.15_suppl.10009 article EN Journal of Clinical Oncology 2018-05-20

Voice based Intelligent Virtual Assistants (IVAs) promise to improve healthcare management and Quality of Life (QOL) by introducing the paradigm hands free eye interactions. However, there has been little understanding regarding challenges for designing such systems older adults, especially when it comes related tasks. To tackle this, we consider processes care delivery QOL enhancements adults as a collaborative task between patients providers. By interviewing 16 living independently or semi...

10.1145/3441852.3471218 preprint EN 2021-10-17

Ecological momentary assessment (EMA) is used to evaluate subjects' behaviors and moods in their natural environments, yet collecting real-time self-report data with EMA challenging due user burden. Integrating voice into collection platforms through today's intelligent virtual assistants (IVAs) promising hands-free eye-free nature. However, efficiently managing conversations EMAs non-trivial time consuming the ambiguity of input. We approach this problem by rethinking modeling questions...

10.1145/3469595.3469626 preprint EN 2021-07-23

The Geriatrics 5Ms: Medications, Mind, Mobility, what Matters most and Multicomplexity is a framework to address the complex needs of older adults. Intelligent Voice Assistants (IVAs) are increasingly popular have potential support health-related We utilized previously collected qualitative data on adults' views how an IVA may their ascertained fit into 5Ms framework. codes describing health challenges solutions framework: (1) Medications: difficulty remembering medications.

10.1177/23337214231201138 article EN cc-by-nc Gerontology and Geriatric Medicine 2023-01-01

We evaluated the feasibility, reliability, and validity of a Spanish-language self-administered geriatric assessment (GA) in older (age ≥ 65) Spanish-speaking women with breast cancer United States. Eligible participants (n = 181) were recruited randomized. Feasibility was defined as participant's unassisted GA completion rate, time, perception on ease completion. Reliability assessed using Spearman's correlation coefficients. Two-sided p < 0.05 considered significant. Ninety-eight percent...

10.3390/cancers13112685 article EN Cancers 2021-05-29

10044 Background: Older patients (pts) with cancer are at risk for depression and anxiety, which often under-recognized. Participation in religious activities has been associated better mental health pts cancer; however, data conflicting few studies focus on older pts. This study explores associations between participation anxiety cancer. Methods: is a secondary analysis of prospective age ≥ 65 Prior to starting new line chemotherapy, self-reported if they felt depressed (yes/no 1-Question...

10.1200/jco.2018.36.15_suppl.10044 article EN Journal of Clinical Oncology 2018-05-20

e18672 Background: By 2060, nearly a quarter of older adults in the US will identify themselves as Hispanic/Latino. We have previously developed self-administered GA tool which can be used to functional, psychological, social and cognitive vulnerabilities with cancer. Among English-speaking adults, answering this using tablet or paper/pencil takes median 15-21 minutes (min), < 10% need assistance complete it (Hurria, JOP 2016). However, has not been tested Spanish-speaking adults. assessed...

10.1200/jco.2018.36.15_suppl.e18672 article EN Journal of Clinical Oncology 2018-05-20

Abstract Background: Older adults with breast cancer receiving neo/adjuvant chemotherapy are at increased risk for toxicity and dose reductions, often leading to decreased relative intensity (dRDI &amp;lt; 85%) potentially compromised benefits. Identifying which older patients projected have dRDI standard regimens could help optimize systemic treatment delivery completion. Methods: We prospectively enrolled aged ≥ 65 who were starting HER2-negative, stage I-III cancer. Geriatric assessment...

10.1158/1538-7445.sabcs19-pd10-10 article EN Cancer Research 2020-02-15

52 Background: Older adults with cancer often have age-associated vulnerabilities and challenges, especially during hospitalization. Geriatric assessment (GA) can help identify such vulnerabilities, generate recommendations, guide the choice of interventions. Recently, GA-driven interventions been shown to decrease chemotherapy toxicity among older in outpatient setting. However, few studies examined its role inpatient Our purpose was evaluate feasibility hospitalized cancer. Methods:...

10.1200/jco.2020.38.29_suppl.52 article EN Journal of Clinical Oncology 2020-10-08

11556 Background: Anxiety and depression are associated with decreased quality of life, treatment adherence, survival in patients cancer. Mental Health Inventory (MHI-17) is a validated screening tool for psychological well-being, but cut points older adults cancer unknown. The goal this study to identify on MHI-17 (MHI-A) Depression (MHI-D) subscales which correlate patient-reported anxiety Methods: This secondary analysis baseline data from randomized controlled trial aged 65+ solid tumors...

10.1200/jco.2019.37.15_suppl.11556 article EN Journal of Clinical Oncology 2019-05-20

<sec> <title>BACKGROUND</title> Older adults are the fastest growing digital technology users. IVAs embodied in smart speakers popular and they accessible to people with sensory, physical cognitive impairments. The geriatrics 5Ms: Medications, Mind, Mobility, what Matters most Multicomplexity, addresses complex care needs of older adults. </sec> <title>OBJECTIVE</title> We examined data on adults’ views how an IVA may address their health-related ascertained fit into 5Ms framework....

10.2196/preprints.42410 preprint EN 2022-09-02

235 Background: The CARG tox score can predict risk of chemotherapy-related in older adults with cancer. GAIN reduce vs standard care (SOC) among these patients (pts); GAIN’s impact across groups is unknown. Methods: A secondary analysis the randomized clinical trial (NCT02517034) pts aged ≥65 (solid tumor diagnosis, starting a new chemotherapy) was performed. Pts were 2:1 to receive SOC and categorized into low (0-5), medium (6-9), high (10-20) according score. primary outcome incidence...

10.1200/jco.2022.40.28_suppl.235 article EN Journal of Clinical Oncology 2022-09-30
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