Brunna Letícia de Oliveira Santana

ORCID: 0000-0003-4402-8358
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About
Contact & Profiles
Research Areas
  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • CAR-T cell therapy research

Universidade de Brasília
2023

Acute Lymphoblastic Leukemia (ALL) is the predominant hematological malignancy in pediatric populations, originating from B- or T-cell precursors within bone marrow. The disease exhibits a high degree of heterogeneity, both at molecular level and terms clinical presentation. A complex interplay between inherited acquired genetic alterations contributes to pathogenesis, often resulting disruption cellular functions integral leukemogenic process. advent CRISPR/Cas9 as gene editing tool has...

10.3389/fphar.2023.1322937 article EN cc-by Frontiers in Pharmacology 2023-12-07
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