Takahiro Tominaga

ORCID: 0000-0003-4403-7414
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Research Areas
  • Advanced Radiotherapy Techniques
  • Radiation Therapy and Dosimetry
  • Radiation Effects and Dosimetry
  • Radiation Detection and Scintillator Technologies
  • Nuclear Physics and Applications
  • Thermal and Kinetic Analysis
  • Radiation Dose and Imaging
  • Luminescence Properties of Advanced Materials
  • Inorganic and Organometallic Chemistry
  • Radiation Shielding Materials Analysis
  • Dark Matter and Cosmic Phenomena
  • Medical Imaging Techniques and Applications
  • Neutrino Physics Research
  • Lanthanide and Transition Metal Complexes
  • Chemical Thermodynamics and Molecular Structure
  • Free Radicals and Antioxidants
  • Organic Chemistry Cycloaddition Reactions
  • Atmospheric Ozone and Climate
  • Injection Molding Process and Properties
  • Adsorption, diffusion, and thermodynamic properties of materials
  • Advanced X-ray and CT Imaging
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Optical measurement and interference techniques
  • Biomedical Research and Pathophysiology
  • Enzyme Structure and Function

Hiroshima International University
2009-2024

Hiroshima University
2015-2017

Keio University Hospital
2017

Tohoku University
2011-2016

Japan Radioisotope Association
2016

Tokyo Metropolitan University
2002

International University
1999

Hokkaido University
1999

Marshall Space Flight Center
1990

Radiosensitization effects caused by high atomic number (Z) metallic nanoparticles have been extensively explored with a wide range of X-ray based radiotherapy beams that seem to provide intriguing results for potential clinical applications. In this study, the radiobiological consequences gold (AuNPs), superparamagnetic iron oxide (SPIONs), Platinum Nanodendrites (PtNDs) and Bismuth Oxide Nanorods (BiNRs) on Human Colon Carcinoma cells (HCT 116) irradiated 150 MeV proton were investigated....

10.1016/j.onano.2018.100027 article EN cc-by-nc-nd OpenNano 2018-11-30

view Abstract Citations (76) References (30) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Energy Spectra of Cosmic Rays above 1 TeV per Nucleon Burnett, T. H. ; Dake, S. Derrickson, J. Fountain, W. F. Fuki, M. Gregory, C. Hayashi, Holynski, R. Iwai, Jones, V. Jurak, A. Lord, Miyamura, O. Oda, Ogata, Parnell, Roberts, E. Strausz, Tabuki, Takahashi, Y. Tominaga, Watts, Wefel, P. Wilczynska, B. Wilczynski, Wilkes, Wolter, Wosiek, JACEE Collaboration Direct...

10.1086/185642 article EN The Astrophysical Journal 1990-01-01

Abstract Introduction: Proton beam radiotherapy is an advanced cancer treatment technique, which would reduce the effects of radiation on surrounding healthy cells. The usage radiosensitizers in this technique might further elevate dose towards Material and methods: present study investigated production intracellular reactive oxygen species (ROS) due to presence individual radiosensitizers, such as bismuth oxide nanoparticles (BiONPs), cisplatin (Cis) or baicalein-rich fraction (BRF) from...

10.2478/pjmpe-2022-0004 article EN Polish Journal of Medical Physics And Engineering 2022-03-01

The aim of this study was to investigate the thermoluminescence (TL) response fabricated 2.3 mol% and 6.0 germanium (Ge) doped flat optical fibres proton irradiation. fundamental dosimetric characteristics have been investigated including dose linearity, reproducibility fading. thermoluminescent dosimeters (TLDs) were used as a reference dosimeter allow relative fibres. results show that Ge-doped offer excellent linearity over range from 1 Gy up 10 with correlation determination (R2) 0.99....

10.1088/1742-6596/851/1/012034 article EN Journal of Physics Conference Series 2017-05-01

The application of a two-dimensional correlation filter to the mode shape visualization piezoelectric devices is described. extracts vibrational patterns from two laser-speckle images driven and resting phases. experimental results demonstrate clearly feasibility proposed technique.

10.1143/jjap.41.3313 article EN Japanese Journal of Applied Physics 2002-05-30

On the NMR dose sensitivities of polyacrylamide-based gel dosimeters irradiated by X-ray, additive effect various inorganic salts (electrolytes) is investigated. Among combination cations (Li+, Na+, K+, Mg2+, Ca2+, Sr2+, Ba2+, Zn2+ and Al3+) anions (Cl−, NO−3 SO2-4), MgCl2 shown to be most effective sensitizer. In result, it suggested that extent increase sensitivity may correlate hydration power rather than anions. Contrary enhancement, depression melting point caused additives also pointed out.

10.1088/1742-6596/444/1/012094 article EN Journal of Physics Conference Series 2013-06-26

Delocalized lipophilic cations such as [ 18 F]fluorobenzyltriphenylphosphonium ([ F]FBnTP) can accumulate in mitochondria and have been used myocardial perfusion imaging (MPI). In this study, we established a simplified method for F]FBnTP synthesis using triphenylphosphine hydrobromide (PPh 3 •HBr) without preparing an intermediate that contains benzyl bromide structure. Applying new method, synthesized evaluated novel F‐labeled PEGylated BnTP derivative F]FPEGBnTP). vitro cellular uptake...

10.1002/jlcr.3379 article EN Journal of Labelled Compounds and Radiopharmaceuticals 2016-02-10

Interest in combining metallic nanoparticles, such as iron (SPIONs), gold (AuNPs) and bismuth oxide (BiONPs), with radiotherapy has increased due to the promising therapeutic advantages. While underlying physical mechanisms of NP-enhanced have been extensively explored, only a few research works were motivated quantify its contribution an experimental dosimetry setting. This work aims explore feasibility radiochromic films measure dose enhancement (DE) caused by release secondary electrons...

10.3390/radiation2010010 article EN cc-by Radiation 2022-03-02

To improve the dose sensitivity of normoxic polyacrylamide gelatin gel (nPAG) dosimeter, effect sucrose as an additive is investigated. The dose-transverse relaxation rate (R2) characteristics samples nPAG with different concentrations were examined, and temperature increases due to exothermic polymerization reaction in irradiated also measured. As result, dose-R2 increased (∼3 times) increasing (0–25%), while other response, such integral property, dependence temporal stability, consistent...

10.1088/1742-6596/250/1/012016 article EN Journal of Physics Conference Series 2010-11-01

We investigate the fundamental characteristics of thermoluminescence (TL) glow curves on fabricated 2.3 and 6.0 mol% germanium (Ge) doped flat optical fibres subjected to proton beam irradiation. The novel Ge-doped used in this study were manufactured using a modified chemical vapour deposition (MCVD) based technique. TLD-100 dosimeters commercial (CorActive High-Tech Inc., Canada) employed allow for comparable TL response fibres. irradiations carried out 150-MeV energy over radiation doses...

10.1063/1.5080897 article EN AIP conference proceedings 2018-01-01

Surgical treatment of deep-seated tumors such as supratentorial intraventricular and thalamic-pineal-tectal region carries a risk postoperative deficits due to possible damage deep cerebral veins including the internal vein. It is often difficult identify whether vessel encountered during surgery needs be preserved or not through small operative field. Therefore, preoperative evaluation venous structures important. We evaluated usefulness 3-Tesla magnetic resonance imaging (3 T MRI) for this...

10.1055/s-0031-1279715 article EN min - Minimally Invasive Neurosurgery 2011-06-01

This paper is intended as a study of the radiological characteristics polymer gel detector in irradiation to 210MeV protons. The depth dose distributions gels were examined with regard its and rate dependences. results indicate energy dependence dose-response relations due LET effect.

10.1088/1742-6596/164/1/012012 article EN Journal of Physics Conference Series 2009-05-01

In this work, the dose response of a methacrylic acid based gel dosimeter containing different concentrations gelatin is examined to clarify role in polymerization process. Direct temperature monitoring throughout irradiation process adopted as method. addition, investigate function on polymerization, another experiments are performed after replacing with some acids. From results, it concluded that an indispensable component reaction which acts "trigger", and peptide structure also assumes...

10.1088/1742-6596/164/1/012019 article EN Journal of Physics Conference Series 2009-05-01

This study aims to investigate the radiation enhancement effects of ultrasound-stimulated microbubbles (USMB) with X-rays and nanoparticles on pancreatic cancer cells

10.4103/jmp.jmp_30_24 article EN cc-by-nc-sa Journal of Medical Physics 2024-07-01

Abstract This paper aims to assess the dose-response characteristics of delaminated GAFCHROMIC™ EBT3 films for radiotherapy beams. Delaminated were produced by peeling off top polyester substrate original using surgical precision forceps. The irradiated 500 cGy with photon beams 6 MV and 10 MV, while proton 192 Ir exposures conducted at nominal energies 150 MeV 0.38 respectively. Digitisations made a flatbed scanner in Red-channel optimum sensitivity. Analyses data fitting, reading...

10.1088/1742-6596/1248/1/012069 article EN Journal of Physics Conference Series 2019-06-01
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