- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical Imaging and Pathology Studies
- Respiratory and Cough-Related Research
- Pulmonary Hypertension Research and Treatments
- Systemic Sclerosis and Related Diseases
- Occupational exposure and asthma
- Pleural and Pulmonary Diseases
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Occupational and environmental lung diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Dysphagia Assessment and Management
- Lung Cancer Treatments and Mutations
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Diet, Metabolism, and Disease
- Airway Management and Intubation Techniques
- Diet and metabolism studies
- Research on Leishmaniasis Studies
- Pneumonia and Respiratory Infections
- Long-Term Effects of COVID-19
- Genetic factors in colorectal cancer
Democritus University of Thrace
2022-2025
University Hospital of Alexandroupolis
2023-2024
Klinikum Fulda
2018-2022
Universitätsklinikum Gießen und Marburg
2014-2020
Institut für Lungenforschung
2020
Universities of Giessen and Marburg Lung Center
2014-2019
German Center for Lung Research
2014-2019
European Central Bank
2018
Justus-Liebig-Universität Gießen
2014-2018
Karger Publishers (Switzerland)
2015
Since 2009, IPF patients across Europe are recruited into the eurIPFreg, providing epidemiological data and biomaterials for translational research. The registry based on patient physician baseline follow-up questionnaires, comprising 1700 parameters. mid- to long-term objectives of provide clues a better understanding phenotype sub-clusters, triggering factors aggravating conditions, regional environmental characteristics, disease behavior management. This paper describes 525 subjects from...
Evidence from large epidemiological studies has shown that obesity may predispose to increased Th2 inflammation and increase the odds of developing asthma. On other hand, there is growing evidence suggesting metabolic dysregulation occurs with obesity, more specifically hyperglycemia insulin resistance, modify immune cell function in some degree systemic inflammation. Insulin resistance seldom on its own, most cases constitutes a clinical component syndrome, along central dyslipidemia....
The aim of this study was to analyze the relative frequency, clinical characteristics, disease onset and progression in f-IPF vs. sporadic IPF (s-IPF). Familial index patients their family members were recruited into European registry/biobank (eurIPFreg) at Universities Giessen Marburg (UGMLC). Initially, we employed wide range criteria (e.g. relatives who presumably died some kind parenchymal lung disease). After narrowing down search occurrence idiopathic interstitial pneumonia (IIP) least...
Pulmonary manifestations of vasculitis are associated with significant morbidity and mortality in affected individuals. They result from a complex interplay between immune dysregulation, which leads to vascular inflammation tissue damage. This review explored the underlying pathogenesis pulmonary involvement vasculitis, encompassing various forms such as granulomatosis polyangiitis (GPA), microscopic (MPA), eosinophilic (EGPA), anti-GBM disease. Mechanisms involving ANCA autoantibodies,...
Background: Sarcoidosis is a granulomatous disease with varying courses of progression. Environmental exposures are thought to be contributors onset. Exposure air pollutants such as fine particulate matter (PM<sub>2.5</sub>) and nitrogen dioxide (NO<sub>2</sub>) have been identified health disparities in lung diseases; little known about these environmental exposures’ associations outcomes sarcoidosis. Research Question: Is higher exposure PM<sub>2.5</sub>...
Type 2 diabetes mellitus (T2DM) is often recognised as a major comorbidity of chronic obstructive pulmonary disease (COPD) and being increasingly linked to elevated risk acute exacerbation (AECOPD). Accordingly the potential utility antidiabetic medication, mostly in subjects suffering from both AECOPD T2DM, has been investigated. The most widely studied medication metformin. Although some studies showed no particular benefit, others assessed diminished by 37% reductions hospitalisations,...
Background: The ILD-GAP scoring system is known to be useful in predicting prognosis patients with interstitial lung disease (ILD). An elevated monocyte count was associated increased risks of IPF poor prognosis. We examined whether the combined ratio (ILD-GAPM) superior conventional model ILD Methods: In treated between April 2013 and 2017, we were retrospectively assessed relationships baseline clinical parameters, including age, sex, Charlson Comorbidity Index score (CCIS), diagnosis,...
There is an increasing interest in employing electronic nose technology the diagnosis and monitoring of lung diseases. Interstitial diseases (ILD) are challenging regard to setting accurate a timely manner. Thus, there high unmet need non-invasive diagnostic tests. This single-center explorative study aimed evaluate usefulness (Aeonose®) ILDs.Exhaled volatile organic compound (VOC) signatures were obtained by Aeonose® 174 ILD patients, 23 patients with chronic obstructive pulmonary disease...
Stroke is a significant cause of mortality and chronic morbidity caused by cardiovascular disease. Respiratory muscles can be affected in stroke survivors, leading to complications, such as respiratory infections. function assessed using pulmonary tests (PFTs). Data regarding PFTs survivors are limited. We reviewed the correlation between severity or degree disability. Furthermore, we PFT change patients undergoing muscle training program. searched PubMed until September 2023 inclusion...
Evidence from large epidemiological studies has shown that obesity may predispose to increased Th2 inflammation and increase the odds of developing asthma. On other hand, there is growing evidence suggesting metabolic dysregulation occurs with obesity, more specifically hyperglycemia insulin resistance, modify immune cell function in some degree systemic inflammation. Insulin resistance seldom on its own, most cases constitutes a clinical component syndrome, along central dyslipidemia....
Background : Previous studies demonstrated the beneficial impact of Mediterranean diet (MedDiet) on metabolic syndrome (MetS). The aim this study was to retrospectively investigate association between MedDiet and MetS in a representative sample Athenian population early 1980s, when had not been established as an entity yet. Methods In cross‐sectional epidemiologic survey cardiovascular disease (CVD), 2,074 randomly selected adults were examined: 900 men 1,174 women (age, 46.9 ± 14.9 years)....
Lung cancer remains one of the leading causes cancer-related mortality worldwide. There is evidence a complex interplay between lung and interstitial disease (ILD), affecting progression, management strategies, patient outcomes. Both conditions develop as result common risk factors such smoking, environmental exposures, genetic predispositions. The presence ILD poses diagnostic therapeutic challenges in management, including difficulties interpreting radiological findings, increased...