A5084900154- Cervical Cancer and HPV Research
- Reproductive tract infections research
- Genital Health and Disease
- Genetic Associations and Epidemiology
- Diabetes and associated disorders
- Retinal Diseases and Treatments
- Calcium signaling and nucleotide metabolism
- Herpesvirus Infections and Treatments
- Retinal Imaging and Analysis
- Cancer-related Molecular Pathways
- Reproductive Physiology in Livestock
- Erythrocyte Function and Pathophysiology
- Urinary Tract Infections Management
- Hepatitis B Virus Studies
- Glycosylation and Glycoproteins Research
- Cellular transport and secretion
- Cardiovascular Function and Risk Factors
- Genetics and Neurodevelopmental Disorders
- RNA modifications and cancer
National Institute of Genomic Medicine
2024-2025
Universidad Vasco de Quiroga
2020-2025
Morelia Institute of Technology
2020
Instituto Politécnico Nacional
2016
Center for Research and Advanced Studies of the National Polytechnic Institute
2016
Two of the microvascular complications in type 2 diabetes (T2D) are diabetic retinopathy (DR), which is most common cause non-traumatic blindness, and kidney disease (DKD); latter generally requires renal replacement therapy. The aim present study was to determine frequency polymorphisms Tumor Necrosis Factor-α, interleukin-6, interleukin-10 (TNF-α, IL-10, IL-6), as well describe clinical laboratory characteristics T2D association with these complications. This included 203 patients T2D, 102...
RhoGDI proteins have been implicated in several human cancers; changes their expression levels shown pro- or anti-tumorigenic effects. Pancreatic Ductal Adenocarcinoma (PDAC) is a complex pathology, with poor prognosis, and most patients die shortly after diagnosis. Efforts focused on understanding the role of RhoGDI's PDAC, specially, RhoGDI1 RhoGDI2. However, RhoGDI3 has not studied relation to cancer PDAC. Here, we characterized functionality its target GTPases, RhoG RhoB pancreatic cell...
ABSTRACT Processes such as cell migration, phagocytosis, endocytosis, and exocytosis refer to the intense exchange of information between internal external environment in cells, known vesicular trafficking. In eukaryotic these essential cellular crosstalks are controlled by Rab GTPases proteins through diverse adaptor like SNAREs complex, coat proteins, phospholipids, kinases, phosphatases, molecular motors, actin, or tubulin cytoskeleton, among others, all necessary for appropriate...
In the last decade, inclusion of HPV DNA testing in cervical cancer screening has provided one best strategies for prevention and timely detection HPV. We conducted a high-throughput genotyping study based on MALDI-TOF mass spectrometry to determine prevalence 24 genotypes, including oncogenic Mexican women correlated results with cytological findings clinical variables. likewise identified risk factors patients infection. Our included 1000 from Sonora, Mexico, who participated campaigns...
Human papillomavirus (HPV) is the most prevalent sexually transmitted infection (STI) worldwide, with popular screening methods including Papanicolaou test and HPV genotyping. However, in clinical practice, coinfections other pathogens are often underestimated. Therefore, our study aims to describe prevalence of STIs vaginosis urogenital samples from patients who had been tested exclusively for genotyping.This analytical, prospective, cross-sectional included 408 males females. Eligible...
Type 2 diabetes mellitus (T2DM) is a complex chronic disease characterized by decreased insulin secretion and the development of resistance. Previous genome-wide association studies demonstrated that single-nucleotide polymorphisms (SNPs) present in genes coding for ion channels involved increase risk developing this disease. We determined 16 SNPs found CACNA1D, KCNQ1, KCNJ11, CACNA1E increased probability T2DM. In work, we performed case-control study 301 Mexican adults, including 201 cases...
Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications reproduction health and quality life. In concordance with the Sustainable Development Goals (SDG), study aimed to investigate prevalence Candida spp., Ureaplasma Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, HSV, Mycoplasma spp. from cervicovaginal samples correlate them gynecological history patients. Methods. Our analytical,...