- Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Chemotherapy-related skin toxicity
- Management of metastatic bone disease
- Effects of Radiation Exposure
- Lung Cancer Diagnosis and Treatment
- Antenna Design and Analysis
- Full-Duplex Wireless Communications
- Advances in Oncology and Radiotherapy
- Polyomavirus and related diseases
- Nonmelanoma Skin Cancer Studies
- Head and Neck Cancer Studies
- Breast Cancer Treatment Studies
- Brain Metastases and Treatment
- Oral health in cancer treatment
- Bone health and treatments
- Lung Cancer Treatments and Mutations
- Glaucoma and retinal disorders
- Ocular Oncology and Treatments
- Radiation Dose and Imaging
- Colorectal and Anal Carcinomas
- Prostate Cancer Diagnosis and Treatment
- Melanoma and MAPK Pathways
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Prostate Cancer Treatment and Research
Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie
2023-2024
Charité - Universitätsmedizin Berlin
2013-2023
Vivantes Klinikum
2004-2023
Tauern Hospital Zell am See
2021
Berlin Heart (Germany)
2018
Praxis für Humangenetik
2012
Klinik und Poliklinik für Strahlentherapie und Radioonkologie
2004
Universität Hamburg
2001-2004
University Medical Center Hamburg-Eppendorf
2004
Jüdisches Krankenhaus Berlin
2002
Summary Merkel cell carcinoma (MCC, ICD‐O M8247/3) is a rare, malignant, primary skin tumor with epithelial and neuroendocrine differentiation. The cells share many morphologic, immunohistochemical, ultrastructural features cutaneous cells. Nevertheless, the of origin MCC unclear. appears clinically as reddish to purple spherical smooth, shiny surface soft turgid, elastic consistency, usually showing rapid growth. Spontaneous often complete regressions are observed. These likely...
Summary Merkel cell carcinoma (MCC, ICD‐O M8247 / 3) is a rare malignant primary skin tumor with epithelial and neuroendocrine differentiation. The neoplastic cells share many morphological, immunohistochemical ultrastructural characteristics of the skin. diagnosis MCC rarely made on clinical grounds. Histological studies are usually required to confirm suspicion. Given frequent occurrence occult lymph node metastasis, sentinel biopsy should be performed once distant metastasis has been...
Abstract Purpose We report results of a multicenter prospective single-arm phase II trial (ARO-2013-04, NCT01948726) moderately accelerated hypofractionated radiotherapy with simultaneous integrated boost (SIB) in patients breast cancer receiving adjuvant after breast-conserving surgery. Methods The eligibility criteria included unifocal an indication for to the whole and tumor bed. received dose 40 Gy bed total 48 16 fractions 2.5 3 Gy, respectively. Radiotherapy could be given either as 3D...
To analyze long-term results of two multicenter prospective single-arm trials (ARO-2010-01 and ARO-2013-04) investigating adjuvant hypofractionated radiotherapy (HF) with simultaneous integrated boost (SIB) after breast-conserving surgery (BCS).Eligible patients had histopathologically confirmed unifocal breast cancer planned for whole irradiation plus to the tumor bed. In both studies, a total dose 40 Gy was applied 48 bed in 16 fractions 2.5 3.0 Gy. Radiotherapy could be given either as...
Zusammenfassung Das Merkelzellkarzinom (MCC, ICD‐O M8247/3) ist ein seltener, maligner, primärer Hauttumor mit epithelialer und neuroendokriner Differenzierung. Die Tumorzellen teilen viele morphologische, immunhistochemische ultrastrukturelle Eigenschaften den Merkel‐Zellen der Haut. Ursprungszelle (cell of origin) des MCC dennoch unklar. imponiert klinisch als rötlich bis violett farbiger kugeliger Tumor glatter glänzender Oberfläche weicher prall‐elastischer Konsistenz, in Regel schnelles...
Zusammenfassung Das Merkelzellkarzinom (MCC, ICD‐O M8247/3) ist ein seltener, maligner, primärer Hauttumor mit epithelialer und neuroendokriner Differenzierung. Die Tumorzellen teilen viele morphologische, immunhistochemische ultrastrukturelle Eigenschaften den Merkelzellen der Haut. Diagnose MCC wird selten klinisch gestellt. Erst histologisch immunhistochemisch Verdacht auf bestätigt. Nachdem eine Fernmetastasierung durch Bildgebung Schnittbildverfahren ausgeschlossen worden ist, sollte...
Hintergrund Nach initial widersprüchlichen Ergebnissen über die Wirksamkeit von Mepitel-Film zur Radiodermatitisprophylaxe im Rahmen der Brustbestrahlung in zwei randomisierten Phase-II-Studien [1, 2] führten Behroozian et al. eine randomisierte Phase-III-Studie durch, um präventive Effektivität abschließend zu beurteilen
Hintergrund Abhängig von der Bestrahlungsdosis und -technik entwickeln bis zu 20% Patienten ein sechs Monate nach thorakaler Strahlentherapie eine Grad-≥ 2-Pneumonitis, klinisch charakterisiert durch Husten, Dyspnoe, Fieber und/oder respiratorische Insuffizienz [1].In Mehrheit Fälle kann dies außerdem einer irreversiblen Fibrose führen, was mit hoher Morbidität potenzieller Mortalität einhergehen kann.Obwohl das Risiko bei definitiven Radiotherapie primären oder sekundären Lungentumoren am...
Merkel cell carcinoma (MCC) is a radiosensitive tumor and the role of radiotherapy in management this disease was newly defined recently published update S2k guideline on Association Scientific Medical Societies Germany (AWMF). While adjuvant bed broadly recommended, irradiation regional nodal region can be performed patients with negative sentinel lymph nodes high-risk factors. In positive nodes, it an alternative to completion lymphadenectomy. The standard dose for remains 50 Gy.
Abstract Purpose Modern digital teaching formats have become increasingly important in recent years, part due to the COVID-19 pandemic. In January 2021, an online-based webinar series was established by German Society for Radiation Oncology (DEGRO) and young DEGRO (yDEGRO) working group. monthly 120-minute courses, selected lecturers teach curricular content as preparation board certification exam radiation oncology. Methods The evaluation of 24 courses between 01.2021 12.2022 performed...