- COVID-19 and Mental Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- COVID-19 Pandemic Impacts
- Mental Health Research Topics
- interferon and immune responses
- Groundwater flow and contamination studies
- Healthcare professionals’ stress and burnout
- Digital Mental Health Interventions
- Long-Term Effects of COVID-19
- Cancer Mechanisms and Therapy
- Autophagy in Disease and Therapy
- Histone Deacetylase Inhibitors Research
- Hydraulic Fracturing and Reservoir Analysis
- Soil and Unsaturated Flow
- MicroRNA in disease regulation
- Immune cells in cancer
- Optimism, Hope, and Well-being
China Medical University
2021-2025
Fourth Affiliated Hospital of China Medical University
2020-2025
Zhejiang University
1998
Metabolic rewiring underlies effective macrophages defense to respond disease microenvironment. However, the underlying mechanisms driving metabolic enhance macrophage effector functions remain unclear. Here, we demonstrated that reprogramming in inflammatory depended on acetylation of CLYBL, a citramalyl-CoA lyase, at lysine 154 (K154), and blocking CLYBL-K154 restricted release pro-inflammatory factors. Mechanistically, found crucial AMPK-CLYBL positive feedback loop, triggered by...
Background COVID-19 is a highly contagious and pathogenic disease caused by novel coronavirus, SARS-CoV-2, it has become pandemic. As vulnerable population, university students are at high risk during the epidemic, as they have mobility often overlook severity of because receive incomplete information about epidemic. In addition to death from infection, epidemic placed substantial psychological pressure on public. this respect, more prone problems induced compared general population for most...
The coronavirus disease-19 (COVID-19) pandemic may result in detrimental consequences for stroke patient's wellbeing. Family functioning and optimism could help patients cope with crises leading to possible improvements life satisfaction. This study aims explore the protective effects of family on satisfaction among during COVID-19 China. was designed as a cross-sectional survey. A total 207 inpatients who were receiving pharmacotherapy rehabilitation general public hospital Liaoning...
Objective: Tripartite motif 66 (TRIM66) is reported to be closely associated with human cancers. However, the roles of TRIM66 in glioma remain unclear. The present study aimed investigate clinical significance and biological glioma. Methods: expression tissues was examined by immunohistochemistry. overexpression siRNA knockdown were performed glioblastoma cell lines. CCK8, colony formation assay, transwell Annexin V JC1 staining, glucose uptake Western blotting used explore potential...
Abstract BackgroundThe novel coronavirus pneumonia (COVID-19) is a highly contagious and pathogenic disease caused by coronavirus(SARS-CoV-2)and has become pandemic within short period of time. The epidemic brought not only the risk death from infection but also unbearable psychological pressure. College students as special group, their mental health status need to be studied during outbreak COVID-19.MethodsWe used Self-Rating Anxiety Scale (SAS), Depression (SDS), compulsive behavior part...
<sec> <title>BACKGROUND</title> COVID-19 is a highly contagious and pathogenic disease caused by novel coronavirus, SARS-CoV-2, it has become pandemic. As vulnerable population, university students are at high risk during the epidemic, as they have mobility often overlook severity of because receive incomplete information about epidemic. In addition to death from infection, epidemic placed substantial psychological pressure on public. this respect, more prone problems induced compared...