Ryan Latimer

ORCID: 0000-0003-4417-8997
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About
Contact & Profiles
Research Areas
  • Microbial Natural Products and Biosynthesis
  • Microbial bioremediation and biosurfactants
  • Enzyme Structure and Function
  • Bacterial Genetics and Biotechnology
  • Pesticide and Herbicide Environmental Studies

Queen's University
2009-2010

CmlS, a flavin-dependent halogenase (FDH) present in the chloramphenicol-biosynthetic pathway Streptomyces venezuelae, directs dichlorination of an acetyl group. The reaction mechanism CmlS is considerable interest as it will help to explain how FDH family can halogenate wide range substrates through common mechanism. protein has been recombinantly expressed Escherichia coli and purified homogeneity. hanging-drop vapour-diffusion method was used produce crystals that were suitable for X-­ray...

10.1107/s1744309108043091 article EN Acta Crystallographica Section F Structural Biology and Crystallization Communications 2009-02-25
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