A5089876539- Cancer, Lipids, and Metabolism
- Multiple Myeloma Research and Treatments
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Lipoproteins and Cardiovascular Health
- Metabolomics and Mass Spectrometry Studies
- Muscle and Compartmental Disorders
- Protein Degradation and Inhibitors
- Acute Lymphoblastic Leukemia research
- Fatty Acid Research and Health
- Platelet Disorders and Treatments
- Drug Transport and Resistance Mechanisms
- Acute Myeloid Leukemia Research
- COVID-19 Clinical Research Studies
- Peptidase Inhibition and Analysis
- Bone and Joint Diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Urological Disorders and Treatments
- Hematological disorders and diagnostics
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and biosynthesis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- CAR-T cell therapy research
- Cancer Treatment and Pharmacology
- Liver Disease Diagnosis and Treatment
University of Belgrade
1989-2025
Zemun Hospital
2016-2025
Kliničko Bolnički Centar Zvezdara
2010-2023
University Children's Hospital, Belgrade
1997
We evaluated coagulation abnormalities via traditional tests and rotational thromboelastometry (ROTEM) in a group of 94 patients with confirmed SARS-CoV-2 infection different severity pneumonia (34 moderate, 25 severe, 35 critical) the hypothesis that ROTEM parameters differed by coronavirus disease 2019 (COVID-19) severity. Shorter than normal clotting time (CT) higher maximum clot firmness (MCF) extrinsic (EXTEM) fibrinogen (FIBTEM), shorter EXTEM formation (CFT), α-angle were classified...
Multiple myeloma (MM) is predominantly a disease of the elderly, but approximately 10% patients are younger than 50 years at diagnosis. METHODS: This study aimed to investigate clinical characteristics, treatment outcomes, and prognostic factors in MM using retrospective data from Balkan Myeloma Study Group registry. RESULTS: A total 350 under old were included, comprising 10.4% overall cohort. The found that had lower rates renal impairment anemia higher incidence lytic bone adverse...
nema
Background: Lung cancer is one of the leading causes cancer-related mortality. Non-small cell lung (NSCLC) and small (SCLC) differ in aggressiveness, proliferation speed, metastasis propensity, prognosis. Since tumor cells notably change lipid metabolism, especially phospholipids fatty acids (FA), this study aimed to identify FA alterations tissues. Methods: Our included patients with newly diagnosed, histologically confirmed SCLC (n = 27) NSCLC 37). Samples were collected from both...
Lipidome dysregulation is a hallmark of cancer and inflammation. The global plasma lipidome sub-lipidome inflammatory pathways have not been reported in diffuse large B-cell lymphoma (DLBCL). In pilot study lipid variation female DLBCL patients BMI-matched disease-free controls, we performed targeted lipidomics using LC-MRM to quantify mediators inflammation immunity, those known or hypothesised be involved progression: sphingolipids, resolvin D1, arachidonic acid (AA)-derived oxylipins,...
Introduction. A bleeding syndrome in the setting of primary hyperfibrinolysis a prostate cancer patient is only 0.40? 1.65% cases. The laboratory diagnosis based on increase biomarkers like D-dimer, fibrinogen split products, plasminogen, and euglobulin lysis test. These tests are not specific for hyperfibrinolysis. We reported rare case hemorrhagic caused by as first clinical symptom metastatic cancer. Case report. 64-year-old male was admitted to our hospital with large hematomas right...
The presence of anemia in patients with heart failure is a significant independent adverse prognostic factor. etiology multifactorial and the nature itself, advanced age, frequent comorbidities contribute to its development. Notably, absolute or functional iron deficiency, even absence anemia, significantly diminishes quality life, increases hospitalization frequency, raises mortality rates failure. intricate pathophysiology present challenge for accurate interpretation laboratory parameters...
In healthy population, uric acid comprises the major component of 10-20% renal stones. Extreme hiperuricaemia is seen in cancer patients with tumor lysis syndrome (TLS) which classically associated haematological malignancies rapid growth rates such as acute lymphoid leukaemia and high grade lymphomas. Primary melofibrosis (Agnogenic myeloid metaplasia- AMM) a chronic myeloproliferative disease characterized by splenomegaly, leukoerythroblastic blood picture, teardrop poikilocytosis varying...
Large B-cell lymphoma (LBCL) is the most common type of non-Hodgkin in general population, constituting 40-50% all NHL cases, and over 60% cases population patients 65 years. Given their increasing life expectancy, prevalence this expected to grow upcoming Treating these a significant challenge due numerous factors that complicate treatment worsen outcome disease. Elderly often have comorbid conditions, weakened organ function, altered drug metabolism, reduced hematopoietic capacity for bone...