- Orthopedic Surgery and Rehabilitation
- Foot and Ankle Surgery
- Bone fractures and treatments
- Diabetic Foot Ulcer Assessment and Management
- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Celiac Disease Research and Management
- Lower Extremity Biomechanics and Pathologies
- Gastrointestinal disorders and treatments
- Rheumatoid Arthritis Research and Therapies
- Meta-analysis and systematic reviews
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Total Knee Arthroplasty Outcomes
- Biosensors and Analytical Detection
- Academic Writing and Publishing
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Blood transfusion and management
- Microfluidic and Capillary Electrophoresis Applications
- Metabolism and Genetic Disorders
- Pelvic and Acetabular Injuries
- Advanced biosensing and bioanalysis techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Health and Medical Research Impacts
Oregon Health & Science University
2020-2025
University of California, San Francisco
2024
Bridge University
2022
Clinical Orthopaedics and Related Research
2020
Committee on Publication Ethics
2020
Hull Royal Infirmary
2015-2016
Oregon State University
2016
Laboratory-based testing does not allow for the sufficiently rapid return of data to enable optimal therapeutic monitoring patients with metabolic diseases such as phenylketonuria (PKU). The typical turn-around time several days current laboratory-based is too slow be practically useful effective or optimizing therapy. This report describes development a rapid, paper-based, point-of-care device phenylalanine detection using small volume (40 μL) whole blood. quantitative resolution and...
Complications such as nonunion and infection following ankle arthrodesis can lead to increased patient morbidity financial burden from repeat operations. Improved knowledge of risk factors improve selection inform post-ankle surveillance protocols.This is a large retrospective, database study with structured query national insurance claims (PearlDiver Technologies) for patients treated 2015 2019 identified by International Classification Diseases, Tenth Revision (ICD-10), codes. Patients any...
Background: Pilon fractures carry high rates of early wound healing, infectious complications, and late posttraumatic arthrosis. When reconstructive procedures are indicated, these patients at further risk for complications. Perhaps using the same direct anterior (DA) approach initial repair later reconstruction might mitigate risks, but DA has not been explored repair. This study aimed to evaluate performance internal fixation pilon fractures. We hypothesized that reoperation rate treated...
International guidelines recommend coeliac serology in iron deficiency anaemia, and duodenal biopsy for those tested positive to detect disease. However, pre-endoscopy is often unavailable, thus committing endoscopists take routine biopsies. Some consider mandatory anaemia exclude other pathologies. We hypothesise that using a point of care test at endoscopy could fill this gap, by providing rapid results target anaemic patients who require biopsies, save costs avoidance. therefore assessed...
Below-the-knee amputation (BKA) is relatively common among patients with vascular disease, infection, trauma, or neoplastic disease. Many BKAs are performed in incompletely treated medical comorbidities, and some acute high-energy trauma crush injuries, malignant neoplasm undergoing time-sensitive limb removal, diabetes active infection sepsis. Consequently, revision common. Prior studies of outcomes after BKA, including several based on the American College Surgeons-National Surgical...
Superior mesenteric artery (SMA) syndrome is an uncommon phenomenon caused by the compression of third portion duodenum between aorta and SMA. Here, we present a previously healthy 15-year-old male who presented with early satiety 20 kg weight loss. Computed tomography (CT) demonstrated massive retroperitoneal liposarcoma displacing entire small intestine into right upper quadrant. Following resection large mass, patient was intolerant oral intake despite evidence bowel function. Abdominal...
Transtibial below-knee amputation (BKA) is associated with considerable morbidity, particularly in the vasculopathic population. The purpose of this study was to determine cumulative probability undergoing transfemoral above-knee (AKA) conversion within 5 years BKA and risk factors while accounting for competing death.This a retrospective, national database structured query Veterans Affairs (VA) patients who underwent from 1999 2020, identified by Current Procedural Terminology codes....
Lisfranc injuries are among the most debilitating to foot. Characterization of first tarsometatarsal (TMT) joint involvement in is limited. Multiple studies have indicated that this damaged a variety injury patterns, but there sparse information regarding how often and what form.A retrospective review was performed operative fractures from 2010 2020 with patients identified by Combined Procedural Terminology codes. Hardcastle Myerson classifications computed tomography radiograph...
Preoperative chemotherapy (POC) is often employed for patients with resectable colorectal liver metastasis (CRLM). The time to resection (TTR) following the end of may impact oncologic outcomes; this phenomenon has not been studied in CRLM.We queried our institutional cancer database resected CRLM after POC from 2003 2019. TTR was calculated date last cytotoxic chemotherapy. Kaplan-Meier analysis and multivariable Cox proportional hazards modeling were used analyze recurrence-free survival...
Category: Trauma; Ankle Introduction/Purpose: The direct anterior (DA) approach is commonly used for reconstructive procedures to treat posttraumatic ankle osteoarthritis (PTOA), however, literature investigating utilization of the DA (defined as interval between tibialis tendon and extensor hallucis longus tendon) initial fixation pilon fractures lacking. This retrospective study patients undergoing hypothesizes that there no difference in reoperation rate whose were treated with approach....
Increasing use of "hype" language (eg, overstating research impact) has been documented in the scientific community. Evaluating abstracts is important because readers may to extrapolate findings entire publications. Our purpose was assess frequency hype within orthopaedic surgery.
Despite over 150000 amputations of lower limbs annually, there remains a wide variation in tourniquet practice patterns and no consensus on their necessity, especially among orthopedic patient populations. The purpose this study was to determine whether use patients undergoing below knee amputation (BKA) associated with difference calculated blood loss relative use.To if BKA use.We performed retrospective review consecutive by surgeons at tertiary care hospital from 2008 through 2018. Blood...
Category: Trauma; Ankle Introduction/Purpose: fractures are one of the most common types foot and ankle trauma requiring surgery. Prior studies have investigated association between obesity fracture on a general level, but not all broken down data by pattern subtypes. The aim this study was to investigate severity fractures, as classified single malleolar (isolated fibular, posterior or medial malleolar), bimalleolar, trimalleolar pilon Methods: We retrospectively patient charts 1,326...
<h3>Introduction</h3> Current BSG iron deficiency anaemia guidelines recommend pre-endoscopy serological testing for coeliac disease (CD) and duodenal biopsy only patients with a positive test. Many attending endoscopy investigation of do not have serology available. Thus the clinician is then committed to perform biopsy. This gap in clinical practice could be bridged by rapid point care test (POCT). We aimed, assess role novel POCT (Simtomax which detects IgA/IgG deamidated gliadin peptide...
Category: Midfoot/Forefoot; Trauma Introduction/Purpose: Lisfranc injuries are among the most debilitating to midfoot. Various classification systems have characterized injury patterns with specific focus on interval between base of second metatarsal and medial cuneiform as well importance ligamentous structures The restraints first tarsometatarsal (TMT) joint bony involvement these remains unclear. Improved knowledge how TMT is affected in will provide information best manage injuries....
Category: Ankle Arthritis; Introduction/Purpose: Multimodal therapies are critical for limiting use of opioids postoperative pain control after orthopaedic procedures. Though NSAIDs and COX-2 inhibitors effective non-opioid adjuncts pain, animal models have demonstrated increased rates nonunion or delayed union in the presence NSAIDs. Nonunion results a protracted course that may warrant longer duration surveillance revision Retrospective studies meta-analyses investigating NSAID bone...
Category: Ankle; Ankle Arthritis Introduction/Purpose: Complications such as nonunion and infection following ankle arthrodesis can lead to increased patient morbidity financial burden from repeat operations. Improved knowledge on complication likelihood associated risk factors improve selection inform post-ankle surveillance protocols. Methods: This is a large retrospective, database study with structured query of national insurance claims (PearlDiver Technologies) for patients treated 2015...
Category: Ankle Introduction/Purpose: Injury to the syndesmotic ligaments can lead prolonged functional limitations and thus, long-term ankle mobility dysfunction if not diagnosed treated appropriately. Obesity has been studied in relation instability but there is a paucity of literature investigating risk associated with other bone fragility characteristics. Additionally, injury complexity Charcot patients remains unstudied. Methods: This large retrospective, database study structured query...