A5021110315- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Computational Drug Discovery Methods
- Receptor Mechanisms and Signaling
- Transgenic Plants and Applications
- thermodynamics and calorimetric analyses
- Glycosylation and Glycoproteins Research
- Data Mining Algorithms and Applications
- Neurobiology and Insect Physiology Research
- Face and Expression Recognition
- Toxin Mechanisms and Immunotoxins
- Neural Networks and Applications
Nanyang Technological University
2022-2025
Universiti Sains Malaysia
2024
Agency for Science, Technology and Research
2024
Reward prediction errors (RPEs) quantify the difference between expected and actual rewards, serving to refine future actions. Although reinforcement learning (RL) provides ample theoretical evidence suggesting that long-term accumulation of these error signals improves efficiency, it remains unclear whether brain uses similar mechanisms. To explore this, we constructed RL-based models used multiregional two-photon calcium imaging in mouse dorsal cortex. We identified a population neurons...
The integration of deep learning and theories reinforcement (RL) is a promising avenue to explore novel hypotheses on reward-based decision-making in humans other animals. Here, we trained RL agents mice the same sensorimotor task with high-dimensional state action space studied representation their respective neural networks. Evaluation thousands network models extensive hyperparameter search revealed that learning-dependent enrichment state-value policy representations...
Given the increasing aging population and rising prevalence of musculoskeletal diseases due to obesity injury, urgent research is needed formulate new treatment alternatives, as current options remain inadequate. Viruses can exacerbate arthritis worsen symptoms in patients with pre-existing osteoarthritis. Over past decade, chikungunya virus (CHIKV) has emerged a significant public health concern, especially Asia South America. Exploring natural products, such berberine, shown promise its...
Background: Memory and cognitive regression are the first symptoms of Alzheimer’s Disease (AD), which may progress to speech mobility challenges affecting around 35% those who over age 80 years old. Preliminary study shows THICAPA Palm Oil Extracted Tocotrienol (POET) is effective in reducing AD Dorosophila melagnoster. Objective: The purpose this elucidate binding interaction between POET towards APP PS1 at molecular level. Method: (PDB ID: 6SZF), 7D8X), their genetic mutation variations...