A5012714050- Stress Responses and Cortisol
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Peptidase Inhibition and Analysis
- Ion channel regulation and function
- Reproductive tract infections research
- Ferrocene Chemistry and Applications
- Bipolar Disorder and Treatment
- Semiconductor materials and interfaces
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
Ludwig-Maximilians-Universität München
2018-2023
University of Duisburg-Essen
2022
Ruhr University Bochum
2017-2019
LWL-Universitätsklinikum Bochum
2019
Center for Integrated Protein Science Munich
2018
Cotranslational modification of the nascent polypeptide chain is one first events during birth a new protein. In eukaryotes, methionine aminopeptidases (MetAPs) cleave off starter methionine, whereas N-acetyl-transferases (NATs) catalyze N-terminal acetylation. MetAPs and NATs compete with other cotranslationally acting chaperones, such as ribosome-associated complex (RAC), protein targeting translocation factors (SRP Sec61) for binding sites at ribosomal tunnel exit. Yet, well-resolved...
Introduction Despite increased use of pre-exposure prophylaxis (PrEP) in Germany, HIV infection rates are not declining and little is known about how this prevention method affects the prevalence sexually transmitted infections (STI) among men who have sex with (MSM). Aim We studied, a large multicentre cohort, STI point prevalence, co-infection rates, anatomical location influence PrEP. Methods The BRAHMS study was prospective cohort conducted at 10 sites seven major German cities that...